Murcko scaffold
2-Thiophenecarboxamide, N-3-pyridinyl- scaffold
18 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 18
- With full pages
- 4
Scaffold SMILES
O=C(Nc1cccnc1)c1cccs1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 18 of 18 chemicals
2-Thiophenecarboxamide, 5-nitro-N-3-pyridinyl-
CAS 502187-68-0C10H7N3O3S
2-Thiophenecarboxamide, N-3-pyridinyl-
CAS 62289-81-0C10H8N2OS
N-(2-Chloropyridin-3-yl)thiophene-2-carboxamide
CAS 91813-35-3C10H7ClN2OS
5-Bromo-N-(pyridin-3-yl)thiophene-2-carboxamide
CAS 582305-87-1C10H7BrN2OS
2-Thiophenecarboxamide, N-(2-((methylsulfonyl)amino)-5-(trifluoromethyl)-3-pyridinyl)-
CAS 141284-57-3C12H10F3N3O3S2
N-(2-Ethoxypyridin-3-yl)thiophene-2-carboxamide
CAS 1210145-41-7C12H12N2O2S
5-Chloro-N-(6-methoxypyridin-3-yl)thiophene-2-carboxamide
CAS 1182417-08-8C11H9ClN2O2S
3-Methyl-N-(pyridin-3-yl)thiophene-2-carboxamide
CAS 1209925-93-8C11H10N2OS
N-(6-(Methylsulfonyl)pyridin-3-yl)thiophene-2-carboxamide
CAS 1241265-21-3C11H10N2O3S2
5-(Hydrazinecarbonyl)-N-(pyridin-3-yl)thiophene-2-carboxamide
CAS 921596-46-5C11H10N4O2S
![Methyl 3-{[(5-chloro-2-thienyl)-carbonyl]amino}pyridine-2-carboxylate chemical structure, C12H9ClN2O3S, CAS 929214-63-1](/s/NTXUAJHTHUMXNT-UHFFFAOYSA-N.svg)
Methyl 3-{[(5-chloro-2-thienyl)-carbonyl]amino}pyridine-2-carboxylate
CAS 929214-63-1C12H9ClN2O3S
![3-{[(5-Chloro-2-thienyl)carbonyl]amino}pyridine-2-carboxylic acid chemical structure, C11H7ClN2O3S, CAS 929214-62-0](/s/ARJDSWQFSYUNSW-UHFFFAOYSA-N.svg)
3-{[(5-Chloro-2-thienyl)carbonyl]amino}pyridine-2-carboxylic acid
CAS 929214-62-0C11H7ClN2O3S
![Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}pyridine-4-carboxylate chemical structure, C12H9ClN2O3S, CAS 929214-67-5](/s/YILXNDXVNCSGEW-UHFFFAOYSA-N.svg)
Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}pyridine-4-carboxylate
CAS 929214-67-5C12H9ClN2O3S
![3-{[(5-Chloro-2-thienyl)carbonyl]amino}pyridine-4-carboxylic acid chemical structure, C11H7ClN2O3S, CAS 929214-66-4](/s/UADCNFPUGBGWPP-UHFFFAOYSA-N.svg)
3-{[(5-Chloro-2-thienyl)carbonyl]amino}pyridine-4-carboxylic acid
CAS 929214-66-4C11H7ClN2O3S
3-Amino-N-(6-methoxy-3-pyridinyl)-2-thiophenecarboxamide
CAS 1282925-93-2C11H11N3O2S
3-Amino-N-3-pyridinyl-2-thiophenecarboxamide
CAS 1248947-57-0C10H9N3OS
tert-Butyl (2-(pyridin-3-ylcarbamoyl)thiophen-3-yl)carbamate
CAS 2355308-57-3C15H17N3O3S
3-Chloro-N-(6-methoxypyridin-3-yl)thiophene-2-carboxamide
CAS 2779183-79-6C11H9ClN2O2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccco1208 chemicals
O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals