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Murcko scaffold

Ring system with 4 rings and 21 atoms

23 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
23
With full pages
5
Scaffold SMILES

c1ccc(CCN2CCC3CC2Cc2ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCN2CCC3CC2Cc2ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-phenylethyl)-, hydrobromide (1:1) chemical structure, C22H28BrNO, CAS 1239-04-9
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-phenylethyl)-, hydrobromide (1:1)
CAS 1239-04-9C22H28BrNO
Phenazocine chemical structure, C22H27NO, CAS 127-35-5
Phenazocine
CAS 127-35-5C22H27NO
Phenazocine, (-)- chemical structure, C22H27NO, CAS 58640-87-2
Phenazocine, (-)-
CAS 58640-87-2C22H27NO
2-(2-(4-Bromoacetamidophenyl)ethyl)-5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphan chemical structure, C24H29BrN2O2, CAS 88467-32-7
2-(2-(4-Bromoacetamidophenyl)ethyl)-5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphan
CAS 88467-32-7C24H29BrN2O2
N-(2,4,5-Trihydroxyphenethyl)normetazocine chemical structure, C22H28INO4, CAS 62228-26-6
N-(2,4,5-Trihydroxyphenethyl)normetazocine
CAS 62228-26-6C22H28INO4
2,6-Methano-3-benzazocine-8,11-beta-diol, 1,2,3,4,5,6-hexahydro-11-alpha-methyl-, 3-phenethyl-, hydrobromide chemical structure, C21H26BrNO2, CAS 63869-43-2
2,6-Methano-3-benzazocine-8,11-beta-diol, 1,2,3,4,5,6-hexahydro-11-alpha-methyl-, 3-phenethyl-, hydrobromide
CAS 63869-43-2C21H26BrNO2
2,6-Methano-3-benzazocine-8,11-beta-diol, 1,2,3,4,5,6-hexahydro-6-methyl-3-phenethyl-, hydrochloride chemical structure, C21H26ClNO2, CAS 63869-44-3
2,6-Methano-3-benzazocine-8,11-beta-diol, 1,2,3,4,5,6-hexahydro-6-methyl-3-phenethyl-, hydrochloride
CAS 63869-44-3C21H26ClNO2
6,11-Dimethyl-3-(2-phenylethyl)-3-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-3-ium-8-olate--hydrogen bromide (1/1) chemical structure, C25H32BrNO, CAS 63869-49-8
6,11-Dimethyl-3-(2-phenylethyl)-3-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-3-ium-8-olate--hydrogen bromide (1/1)
CAS 63869-49-8C25H32BrNO
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-(p-aminophenethyl)-6,11-alpha-dimethyl- chemical structure, C22H28N2O, CAS 63869-50-1
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-(p-aminophenethyl)-6,11-alpha-dimethyl-
CAS 63869-50-1C22H28N2O
6-Methyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen bromide (1/1) chemical structure, C21H26BrNO, CAS 63870-08-6
6-Methyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen bromide (1/1)
CAS 63870-08-6C21H26BrNO
2,6-Methano-3-benzazocin-11-beta-ol, 1,2,3,4,5,6-hexahydro-8-methoxy-6-methyl-3-phenethyl-, hydrobromide chemical structure, C22H28BrNO2, CAS 63870-09-7
2,6-Methano-3-benzazocin-11-beta-ol, 1,2,3,4,5,6-hexahydro-8-methoxy-6-methyl-3-phenethyl-, hydrobromide
CAS 63870-09-7C22H28BrNO2
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6-ethyl-3-phenethyl-, hydrochloride chemical structure, C22H28ClNO, CAS 63870-10-0
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6-ethyl-3-phenethyl-, hydrochloride
CAS 63870-10-0C22H28ClNO
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-alpha-dimethyl-3-phenethyl-, acetate (ester), hydrobromide chemical structure, C24H30BrNO2, CAS 63870-13-3
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-alpha-dimethyl-3-phenethyl-, acetate (ester), hydrobromide
CAS 63870-13-3C24H30BrNO2
Phenazocine hydrobromide, (+)- chemical structure, C22H28BrNO, CAS 63903-74-2
Phenazocine hydrobromide, (+)-
CAS 63903-74-2C22H28BrNO
Phenazocine, (+)- chemical structure, C22H27NO, CAS 64023-93-4
Phenazocine, (+)-
CAS 64023-93-4C22H27NO
6,11-Dimethyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen bromide (1/1) chemical structure, C22H28BrNO, CAS 63903-75-3
6,11-Dimethyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen bromide (1/1)
CAS 63903-75-3C22H28BrNO
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-alpha-dimethyl-3-((p-methoxy)phenethyl)-, hydrobromide chemical structure, C23H30BrNO2, CAS 63903-77-5
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-alpha-dimethyl-3-((p-methoxy)phenethyl)-, hydrobromide
CAS 63903-77-5C23H30BrNO2
6,11-Diethyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen bromide (1/1) chemical structure, C24H32BrNO, CAS 63915-46-8
6,11-Diethyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol--hydrogen bromide (1/1)
CAS 63915-46-8C24H32BrNO
6,11-Dimethyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine chemical structure, C22H27N, CAS 101771-75-9
6,11-Dimethyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine
CAS 101771-75-9C22H27N
1,2,3,4,5,6-Hexahydro-5,6-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol chemical structure, C22H27NO, CAS 54395-60-7
1,2,3,4,5,6-Hexahydro-5,6-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol
CAS 54395-60-7C22H27NO
Phenazocine hydrobromide chemical structure, C22H28BrNO, CAS 58918-34-6
Phenazocine hydrobromide
CAS 58918-34-6C22H28BrNO
2,6-Methano-3-benzazocin-8-ol, 3-(2-(4-azidophenyl)ethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2S-(2alpha,6alpha,11R*))- chemical structure, C22H26N4O, CAS 135250-44-1
2,6-Methano-3-benzazocin-8-ol, 3-(2-(4-azidophenyl)ethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2S-(2alpha,6alpha,11R*))-
CAS 135250-44-1C22H26N4O
rel-(2R,6R,11R)-3-(2-(4-Fluorophenyl)ethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol chemical structure, C22H26FNO, CAS 86495-14-9
rel-(2R,6R,11R)-3-(2-(4-Fluorophenyl)ethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol
CAS 86495-14-9C22H26FNO