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Murcko scaffold

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-phenylacetamide scaffold

24 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 31
Chemicals: 24
With full pages: 16

Scaffold SMILES

O=C(COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-phenylacetamide page

Murcko scaffold O=C(COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-phenylacetamide chemical structure, C24H25N3O4, CAS 898440-53-4

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-phenylacetamide

CAS 898440-53-4C₂₄H₂₅N₃O₄

2-((6-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide chemical structure, C25H27N3O5, CAS 898440-56-7

2-((6-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide

CAS 898440-56-7C₂₅H₂₇N₃O₅

2-((6-((4-(2-Methoxyphenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide chemical structure, C25H27N3O5, CAS 898416-95-0

2-((6-((4-(2-Methoxyphenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide

CAS 898416-95-0C₂₅H₂₇N₃O₅

N-(2,3-Dimethylphenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C26H29N3O4, CAS 898417-16-8

N-(2,3-Dimethylphenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898417-16-8C₂₆H₂₉N₃O₄

N-(2,5-Dimethylphenyl)-2-[(6-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]acetamide chemical structure, C27H31N3O5, CAS 903330-60-9

N-(2,5-Dimethylphenyl)-2-[(6-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]acetamide

CAS 903330-60-9C₂₇H₃₁N₃O₅

N-(2-Methoxyphenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C25H27N3O5, CAS 898456-17-2

N-(2-Methoxyphenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898456-17-2C₂₅H₂₇N₃O₅

N-(3-Methoxyphenyl)-2-((4-oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)acetamide chemical structure, C25H27N3O5, CAS 898456-20-7

N-(3-Methoxyphenyl)-2-((4-oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)acetamide

CAS 898456-20-7C₂₅H₂₇N₃O₅

N-(4-Methoxyphenyl)-2-((4-oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)acetamide chemical structure, C25H27N3O5, CAS 898440-89-6

N-(4-Methoxyphenyl)-2-((4-oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)acetamide

CAS 898440-89-6C₂₅H₂₇N₃O₅

N-Methyl-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)-N-phenylacetamide chemical structure, C25H27N3O4, CAS 898420-58-1

N-Methyl-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)-N-phenylacetamide

CAS 898420-58-1C₂₅H₂₇N₃O₄

2-[(6-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]-N-phenylacetamide chemical structure, C24H24FN3O4, CAS 898455-78-2

2-[(6-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]-N-phenylacetamide

CAS 898455-78-2C₂₄H₂₄FN₃O₄

2-((6-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(m-tolyl)acetamide chemical structure, C26H29N3O5, CAS 903285-42-7

2-((6-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-(m-tolyl)acetamide

CAS 903285-42-7C₂₆H₂₉N₃O₅

N-(4-Ethoxyphenyl)-2-((6-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide chemical structure, C26H28FN3O5, CAS 903297-22-3

N-(4-Ethoxyphenyl)-2-((6-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)acetamide

CAS 903297-22-3C₂₆H₂₈FN₃O₅

N-(4-Ethoxyphenyl)-2-[(6-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]acetamide chemical structure, C26H28FN3O5, CAS 903332-32-1

N-(4-Ethoxyphenyl)-2-[(6-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]acetamide

CAS 903332-32-1C₂₆H₂₈FN₃O₅

N-(2,4-Dimethoxyphenyl)-2-[(6-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]acetamide chemical structure, C26H28FN3O6, CAS 906150-07-0

N-(2,4-Dimethoxyphenyl)-2-[(6-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]acetamide

CAS 906150-07-0C₂₆H₂₈FN₃O₆

2-[(6-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]-N-(3-nitrophenyl)acetamide chemical structure, C24H23FN4O6, CAS 903333-13-1

2-[(6-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]-N-(3-nitrophenyl)acetamide

CAS 903333-13-1C₂₄H₂₃FN₄O₆

2-[(6-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]-N-phenylacetamide chemical structure, C24H24FN3O4, CAS 898416-92-7

2-[(6-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}-4-oxo-4H-pyran-3-yl)oxy]-N-phenylacetamide

CAS 898416-92-7C₂₄H₂₄FN₃O₄

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-(o-tolyl)acetamide chemical structure, C25H27N3O4, CAS 898417-01-1

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-(o-tolyl)acetamide

CAS 898417-01-1C₂₅H₂₇N₃O₄

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-(m-tolyl)acetamide chemical structure, C25H27N3O4, CAS 898440-68-1

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-(m-tolyl)acetamide

CAS 898440-68-1C₂₅H₂₇N₃O₄

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-(p-tolyl)acetamide chemical structure, C25H27N3O4, CAS 898440-73-8

2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-(p-tolyl)acetamide

CAS 898440-73-8C₂₅H₂₇N₃O₄

N-(3,5-Dimethylphenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C26H29N3O4, CAS 898417-23-7

N-(3,5-Dimethylphenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898417-23-7C₂₆H₂₉N₃O₄

N-(4-Ethylphenyl)-2-((4-oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)acetamide chemical structure, C26H29N3O4, CAS 898417-25-9

N-(4-Ethylphenyl)-2-((4-oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)acetamide

CAS 898417-25-9C₂₆H₂₉N₃O₄

N-(2-Fluorophenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C24H24FN3O4, CAS 898420-72-9

N-(2-Fluorophenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898420-72-9C₂₄H₂₄FN₃O₄

N-(3-Fluorophenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C24H24FN3O4, CAS 898439-71-9

N-(3-Fluorophenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898439-71-9C₂₄H₂₄FN₃O₄

N-(4-Fluorophenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide chemical structure, C24H24FN3O4, CAS 898420-76-3

N-(4-Fluorophenyl)-2-({4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-4H-pyran-3-yl}oxy)acetamide

CAS 898420-76-3C₂₄H₂₄FN₃O₄