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Murcko scaffold

5-(2-Furyl)-3-phenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole scaffold

20 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
20
With full pages
8
Scaffold SMILES

O=S(=O)(c1ccccc1)N1N=C(c2ccccc2)CC1c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(2-Furyl)-3-phenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole page
Murcko scaffold O=S(=O)(c1ccccc1)N1N=C(c2ccccc2)CC1c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

5-(2-Furyl)-3-phenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole chemical structure, C19H16N2O3S, CAS 499116-42-6
5-(2-Furyl)-3-phenyl-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazole
CAS 499116-42-6C19H16N2O3S
N-{4-[1-[(4-Fluorophenyl)sulfonyl]-5-(2-furyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethanesulfonamide chemical structure, C21H20FN3O5S2, CAS 832686-20-1
N-{4-[1-[(4-Fluorophenyl)sulfonyl]-5-(2-furyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethanesulfonamide
CAS 832686-20-1C21H20FN3O5S2
N-(4-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C21H21N3O5S2, CAS 851781-57-2
N-(4-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851781-57-2C21H21N3O5S2
N-(3-(1-((4-Fluorophenyl)sulfonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C21H20FN3O5S2, CAS 851782-91-7
N-(3-(1-((4-Fluorophenyl)sulfonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851782-91-7C21H20FN3O5S2
2-(Benzenesulfonyl)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazole chemical structure, C19H15ClN2O3S, CAS 488135-68-8
2-(Benzenesulfonyl)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazole
CAS 488135-68-8C19H15ClN2O3S
5-(Furan-2-yl)-1-(phenylsulfonyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazole chemical structure, C20H18N2O3S, CAS 131336-76-0
5-(Furan-2-yl)-1-(phenylsulfonyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazole
CAS 131336-76-0C20H18N2O3S
3-(4-Bromophenyl)-5-(furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazole chemical structure, C20H17BrN2O3S, CAS 391890-06-5
3-(4-Bromophenyl)-5-(furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazole
CAS 391890-06-5C20H17BrN2O3S
N-(4-(5-(Furan-2-yl)-1-((4-methoxyphenyl)sulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C21H21N3O6S2, CAS 851780-98-8
N-(4-(5-(Furan-2-yl)-1-((4-methoxyphenyl)sulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851780-98-8C21H21N3O6S2
N-[3-[2-(4-Chlorophenyl)sulfonyl-3-(furan-2-yl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide chemical structure, C20H18ClN3O5S2, CAS 851782-28-0
N-[3-[2-(4-Chlorophenyl)sulfonyl-3-(furan-2-yl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide
CAS 851782-28-0C20H18ClN3O5S2
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C20H18ClN3O5S2, CAS 851780-93-3
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851780-93-3C20H18ClN3O5S2
N-(4-(5-(Furan-2-yl)-1-((4-methoxyphenyl)sulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C22H23N3O6S2, CAS 851781-59-4
N-(4-(5-(Furan-2-yl)-1-((4-methoxyphenyl)sulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851781-59-4C22H23N3O6S2
N-(4-(5-(Furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C21H21N3O5S2, CAS 851780-97-7
N-(4-(5-(Furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851780-97-7C21H21N3O5S2
N-(4-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C20H19N3O5S2, CAS 851780-96-6
N-(4-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851780-96-6C20H19N3O5S2
N-(3-(5-(Furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C22H23N3O5S2, CAS 851782-89-3
N-(3-(5-(Furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851782-89-3C22H23N3O5S2
N-(4-(5-(Furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C22H23N3O5S2, CAS 851781-58-3
N-(4-(5-(Furan-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851781-58-3C22H23N3O5S2
N-(3-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C20H19N3O5S2, CAS 851782-30-4
N-(3-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851782-30-4C20H19N3O5S2
N-(3-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C21H21N3O5S2, CAS 851782-88-2
N-(3-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851782-88-2C21H21N3O5S2
N-[3-[2-(4-Fluorophenyl)sulfonyl-3-(furan-2-yl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide chemical structure, C20H18FN3O5S2, CAS 851782-32-6
N-[3-[2-(4-Fluorophenyl)sulfonyl-3-(furan-2-yl)-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide
CAS 851782-32-6C20H18FN3O5S2
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C21H20ClN3O5S2, CAS 851781-56-1
N-(4-(1-((4-Chlorophenyl)sulfonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851781-56-1C21H20ClN3O5S2
4-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenol chemical structure, C19H16N2O4S, CAS 868155-39-9
4-(5-(Furan-2-yl)-1-(phenylsulfonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenol
CAS 868155-39-9C19H16N2O4S