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Murcko scaffold

4-(Benzenesulfonyl)-2-phenyl-5-pyrrolidin-1-yl-1,3-oxazole scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
12
With full pages
4
Scaffold SMILES

O=S(=O)(c1ccccc1)c1nc(-c2ccccc2)oc1N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Benzenesulfonyl)-2-phenyl-5-pyrrolidin-1-yl-1,3-oxazole page
Murcko scaffold O=S(=O)(c1ccccc1)c1nc(-c2ccccc2)oc1N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-(Benzenesulfonyl)-2-phenyl-5-pyrrolidin-1-yl-1,3-oxazole chemical structure, C19H18N2O3S, CAS 378225-00-4
4-(Benzenesulfonyl)-2-phenyl-5-pyrrolidin-1-yl-1,3-oxazole
CAS 378225-00-4C19H18N2O3S
4-((4-Chlorophenyl)sulfonyl)-2-(4-fluorophenyl)-5-(pyrrolidin-1-yl)oxazole chemical structure, C19H16ClFN2O3S, CAS 823828-35-9
4-((4-Chlorophenyl)sulfonyl)-2-(4-fluorophenyl)-5-(pyrrolidin-1-yl)oxazole
CAS 823828-35-9C19H16ClFN2O3S
2-(2-Chlorophenyl)-4-(4-methylbenzenesulfonyl)-5-(pyrrolidin-1-yl)-1,3-oxazole chemical structure, C20H19ClN2O3S, CAS 380190-57-8
2-(2-Chlorophenyl)-4-(4-methylbenzenesulfonyl)-5-(pyrrolidin-1-yl)-1,3-oxazole
CAS 380190-57-8C20H19ClN2O3S
4-(4-Methylbenzenesulfonyl)-2-phenyl-5-(pyrrolidin-1-yl)-1,3-oxazole chemical structure, C20H20N2O3S, CAS 377766-05-7
4-(4-Methylbenzenesulfonyl)-2-phenyl-5-(pyrrolidin-1-yl)-1,3-oxazole
CAS 377766-05-7C20H20N2O3S
4-(Phenylsulfonyl)-5-(pyrrolidin-1-yl)-2-(o-tolyl)oxazole chemical structure, C20H20N2O3S, CAS 855714-71-5
4-(Phenylsulfonyl)-5-(pyrrolidin-1-yl)-2-(o-tolyl)oxazole
CAS 855714-71-5C20H20N2O3S
4-(Benzenesulfonyl)-2-(4-methoxyphenyl)-5-(pyrrolidin-1-yl)-1,3-oxazole chemical structure, C20H20N2O4S, CAS 855714-96-4
4-(Benzenesulfonyl)-2-(4-methoxyphenyl)-5-(pyrrolidin-1-yl)-1,3-oxazole
CAS 855714-96-4C20H20N2O4S
4-(4-Methylbenzenesulfonyl)-2-(4-methylphenyl)-5-(pyrrolidin-1-yl)-1,3-oxazole chemical structure, C21H22N2O3S, CAS 862737-51-7
4-(4-Methylbenzenesulfonyl)-2-(4-methylphenyl)-5-(pyrrolidin-1-yl)-1,3-oxazole
CAS 862737-51-7C21H22N2O3S
2-(2-Chlorophenyl)-4-(phenylsulfonyl)-5-(pyrrolidin-1-yl)oxazole chemical structure, C19H17ClN2O3S, CAS 862795-46-8
2-(2-Chlorophenyl)-4-(phenylsulfonyl)-5-(pyrrolidin-1-yl)oxazole
CAS 862795-46-8C19H17ClN2O3S
2-(2-Fluorophenyl)-4-(phenylsulfonyl)-5-(pyrrolidin-1-yl)oxazole chemical structure, C19H17FN2O3S, CAS 862797-56-6
2-(2-Fluorophenyl)-4-(phenylsulfonyl)-5-(pyrrolidin-1-yl)oxazole
CAS 862797-56-6C19H17FN2O3S
2-(2-Fluorophenyl)-4-((4-fluorophenyl)sulfonyl)-5-(pyrrolidin-1-yl)oxazole chemical structure, C19H16F2N2O3S, CAS 862798-52-5
2-(2-Fluorophenyl)-4-((4-fluorophenyl)sulfonyl)-5-(pyrrolidin-1-yl)oxazole
CAS 862798-52-5C19H16F2N2O3S
4-(Phenylsulfonyl)-5-(pyrrolidin-1-yl)-2-(p-tolyl)oxazole chemical structure, C20H20N2O3S, CAS 862737-50-6
4-(Phenylsulfonyl)-5-(pyrrolidin-1-yl)-2-(p-tolyl)oxazole
CAS 862737-50-6C20H20N2O3S
4-((4-Chlorophenyl)sulfonyl)-2-(2-fluorophenyl)-5-(pyrrolidin-1-yl)oxazole chemical structure, C19H16ClFN2O3S, CAS 862799-04-0
4-((4-Chlorophenyl)sulfonyl)-2-(2-fluorophenyl)-5-(pyrrolidin-1-yl)oxazole
CAS 862799-04-0C19H16ClFN2O3S