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Murcko scaffold

Ring system with 4 rings and 25 atoms

19 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
19
With full pages
6
Scaffold SMILES

O=S(=O)(c1ccccc1)N1N=C(c2ccccc2)CC1c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1N=C(c2ccccc2)CC1c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-{3-[1-(Phenylsulfonyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethanesulfonamide chemical structure, C21H21N3O4S3, CAS 714263-26-0
N-{3-[1-(Phenylsulfonyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethanesulfonamide
CAS 714263-26-0C21H21N3O4S3
N-{3-[1-(Phenylsulfonyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide chemical structure, C20H19N3O4S3, CAS 833434-30-3
N-{3-[1-(Phenylsulfonyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide
CAS 833434-30-3C20H19N3O4S3
N-[4-[2-(4-Chlorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide chemical structure, C20H18ClN3O4S3, CAS 838817-54-2
N-[4-[2-(4-Chlorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide
CAS 838817-54-2C20H18ClN3O4S3
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C21H20FN3O4S3, CAS 851781-98-1
N-(4-(1-((4-Fluorophenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851781-98-1C21H20FN3O4S3
N-(4-(1-(Phenylsulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C20H19N3O4S3, CAS 851781-24-3
N-(4-(1-(Phenylsulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851781-24-3C20H19N3O4S3
N-(4-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C22H23N3O5S3, CAS 851781-97-0
N-(4-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851781-97-0C22H23N3O5S3
N-[4-[2-(4-Methylphenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide chemical structure, C22H23N3O4S3, CAS 851781-96-9
N-[4-[2-(4-Methylphenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide
CAS 851781-96-9C22H23N3O4S3
N-[4-[2-(4-Fluorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide chemical structure, C20H18FN3O4S3, CAS 851781-26-5
N-[4-[2-(4-Fluorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamide
CAS 851781-26-5C20H18FN3O4S3
N-(4-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C21H21N3O5S3, CAS 851781-25-4
N-(4-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851781-25-4C21H21N3O5S3
N-(3-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C21H21N3O5S3, CAS 851782-56-4
N-(3-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851782-56-4C21H21N3O5S3
N-(3-(5-(Thiophen-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C21H21N3O4S3, CAS 851782-55-3
N-(3-(5-(Thiophen-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851782-55-3C21H21N3O4S3
N-[3-[2-(4-Chlorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide chemical structure, C21H20ClN3O4S3, CAS 851783-15-8
N-[3-[2-(4-Chlorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide
CAS 851783-15-8C21H20ClN3O4S3
N-(3-(5-(Thiophen-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C22H23N3O4S3, CAS 851783-18-1
N-(3-(5-(Thiophen-2-yl)-1-tosyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851783-18-1C22H23N3O4S3
N-(3-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C22H23N3O5S3, CAS 851783-19-2
N-(3-(1-((4-Methoxyphenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 851783-19-2C22H23N3O5S3
N-[3-[2-(4-Fluorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide chemical structure, C21H20FN3O4S3, CAS 851783-20-5
N-[3-[2-(4-Fluorophenyl)sulfonyl-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide
CAS 851783-20-5C21H20FN3O4S3
N-(3-(1-((4-Fluorophenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C20H18FN3O4S3, CAS 851782-57-5
N-(3-(1-((4-Fluorophenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851782-57-5C20H18FN3O4S3
N-(3-(1-((4-Chlorophenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C20H18ClN3O4S3, CAS 851782-53-1
N-(3-(1-((4-Chlorophenyl)sulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851782-53-1C20H18ClN3O4S3
N-[4-[2-(Benzenesulfonyl)-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide chemical structure, C21H21N3O4S3, CAS 851781-95-8
N-[4-[2-(Benzenesulfonyl)-3-thiophen-2-yl-3,4-dihydropyrazol-5-yl]phenyl]ethanesulfonamide
CAS 851781-95-8C21H21N3O4S3
N-{4-[1-(4-Chlorobenzenesulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethane-1-sulfonamide chemical structure, C21H20ClN3O4S3, CAS 851781-93-6
N-{4-[1-(4-Chlorobenzenesulfonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethane-1-sulfonamide
CAS 851781-93-6C21H20ClN3O4S3