Murcko scaffold
Ring system with 4 rings and 20 atoms
8 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 20
- Chemicals
- 8
- With full pages
- 3
Scaffold SMILES
c1ccc2c(c1)CCc1sccc1C2=C1CCNCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
Pizotifen
CAS 15574-96-6C19H21NS
Pizotifen malate
CAS 5189-11-7C23H27NO5S
![2-(1-Methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-9-ol chemical structure, C19H21NOS, CAS 43076-08-0](/s/ZSHTUWQHLKCHLO-UHFFFAOYSA-N.svg)
2-(1-Methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-9-ol
CAS 43076-08-0C19H21NOS
10-Hydroxyketotifen
CAS 43076-12-6C19H21NOS
Pizotyline hydrochloride
CAS 73391-87-4C19H22ClNS
Piperidine, 4-(9,10-dihydro-10-methyl-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-, (Z)-2-butenedioate (1:1)
CAS 59275-17-1C24H27NO4S
Pizotifen maleate
CAS 24359-22-6C23H25NO4S
Pizotifen N-oxide
CAS 28588-48-9C19H21NOS
Related scaffolds
Same ring framework with different atoms or bond orders
