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Murcko scaffold

Ring system with 4 rings and 20 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
5
With full pages
1
Scaffold SMILES

O=C1C=CC2C(=C1)CCC1C3CCC(=O)OC3CCC21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC2C(=C1)CCC1C3CCC(=O)OC3CCC21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Testolactone chemical structure, C19H24O3, CAS 968-93-4
Testolactone
CAS 968-93-4C19H24O3
11beta,13-Dihydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone chemical structure, C19H24O4, CAS 13258-78-1
11beta,13-Dihydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone
CAS 13258-78-1C19H24O4
4-Hydroxy-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene-2,8(4bh)-dione chemical structure, C19H24O4, CAS 6967-26-6
4-Hydroxy-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene-2,8(4bh)-dione
CAS 6967-26-6C19H24O4
3-Hydroxy-10a,12a-dimethyl-4,4a,4b,5,6,10b,11,12-octahydro-3H-naphtho[2,1-f]chromene-2,8-dione chemical structure, C19H24O4, CAS 2484-41-5
3-Hydroxy-10a,12a-dimethyl-4,4a,4b,5,6,10b,11,12-octahydro-3H-naphtho[2,1-f]chromene-2,8-dione
CAS 2484-41-5C19H24O4
(4aS,4bS,10aS,10bR,11S,12aS)-10b-Fluoro-11-hydroxy-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene-2,8(4bh)-dione chemical structure, C19H23FO4, CAS 13258-79-2
(4aS,4bS,10aS,10bR,11S,12aS)-10b-Fluoro-11-hydroxy-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene-2,8(4bh)-dione
CAS 13258-79-2C19H23FO4