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Murcko scaffold

1-(Morpholin-4-yl)-2-(1H-pyrazol-1-yl)ethan-1-one scaffold

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
21
With full pages
3
Scaffold SMILES

O=C(Cn1cccn1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Morpholin-4-yl)-2-(1H-pyrazol-1-yl)ethan-1-one page
Murcko scaffold O=C(Cn1cccn1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

4-({3-Nitro-5-methyl-1H-pyrazol-1-yl}acetyl)morpholine chemical structure, C10H14N4O4, CAS 488822-32-8
4-({3-Nitro-5-methyl-1H-pyrazol-1-yl}acetyl)morpholine
CAS 488822-32-8C10H14N4O4
1-Morpholin-4-yl-2-(4-nitropyrazol-1-yl)ethanone chemical structure, C9H12N4O4, CAS 482573-95-5
1-Morpholin-4-yl-2-(4-nitropyrazol-1-yl)ethanone
CAS 482573-95-5C9H12N4O4
4-({4-Nitro-3,5-dimethyl-1H-pyrazol-1-yl}acetyl)morpholine chemical structure, C11H16N4O4, CAS 358731-78-9
4-({4-Nitro-3,5-dimethyl-1H-pyrazol-1-yl}acetyl)morpholine
CAS 358731-78-9C11H16N4O4
1-Morpholin-4-yl-2-(3-nitropyrazolyl)ethan-1-one chemical structure, C9H12N4O4, CAS 955969-67-2
1-Morpholin-4-yl-2-(3-nitropyrazolyl)ethan-1-one
CAS 955969-67-2C9H12N4O4
2-(5-Methyl-3,4-dinitropyrazol-1-yl)-1-morpholin-4-ylethanone chemical structure, C10H13N5O6, CAS 353455-15-9
2-(5-Methyl-3,4-dinitropyrazol-1-yl)-1-morpholin-4-ylethanone
CAS 353455-15-9C10H13N5O6
2-(4-Amino-1H-pyrazol-1-yl)-1-(morpholin-4-yl)ethan-1-one chemical structure, C9H14N4O2, CAS 1152914-16-3
2-(4-Amino-1H-pyrazol-1-yl)-1-(morpholin-4-yl)ethan-1-one
CAS 1152914-16-3C9H14N4O2
2-(4-Amino-1H-pyrazol-1-yl)-1-(2,6-dimethylmorpholin-4-yl)ethan-1-one chemical structure, C11H18N4O2, CAS 1156075-58-9
2-(4-Amino-1H-pyrazol-1-yl)-1-(2,6-dimethylmorpholin-4-yl)ethan-1-one
CAS 1156075-58-9C11H18N4O2
2-(4-Amino-1H-pyrazol-1-yl)-1-(2,2-dimethylmorpholin-4-yl)ethan-1-one chemical structure, C11H18N4O2, CAS 1154969-57-9
2-(4-Amino-1H-pyrazol-1-yl)-1-(2,2-dimethylmorpholin-4-yl)ethan-1-one
CAS 1154969-57-9C11H18N4O2
1-(4-Morpholinyl)-2-(4-bromo-1H-pyrazol-1-yl)ethanone chemical structure, C9H12BrN3O2, CAS 1178206-51-3
1-(4-Morpholinyl)-2-(4-bromo-1H-pyrazol-1-yl)ethanone
CAS 1178206-51-3C9H12BrN3O2
1-(2-Methylmorpholino)-2-(1H-pyrazol-1-yl)ethan-1-one chemical structure, C10H15N3O2, CAS 1223167-92-7
1-(2-Methylmorpholino)-2-(1H-pyrazol-1-yl)ethan-1-one
CAS 1223167-92-7C10H15N3O2
1-(Morpholin-4-yl)-2-(1H-pyrazol-1-yl)propan-1-one chemical structure, C10H15N3O2, CAS 1223386-75-1
1-(Morpholin-4-yl)-2-(1H-pyrazol-1-yl)propan-1-one
CAS 1223386-75-1C10H15N3O2
1-(3-Methylmorpholin-4-yl)-2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]ethan-1-one chemical structure, C11H14F3N3O2, CAS 1223723-53-2
1-(3-Methylmorpholin-4-yl)-2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]ethan-1-one
CAS 1223723-53-2C11H14F3N3O2
1-(Morpholin-4-yl)-2-(1H-pyrazol-1-yl)ethan-1-one chemical structure, C9H13N3O2, CAS 1205506-17-7
1-(Morpholin-4-yl)-2-(1H-pyrazol-1-yl)ethan-1-one
CAS 1205506-17-7C9H13N3O2
2-(3-Amino-1H-pyrazol-1-yl)-1-(morpholin-4-yl)ethan-1-one chemical structure, C9H14N4O2, CAS 1179611-54-1
2-(3-Amino-1H-pyrazol-1-yl)-1-(morpholin-4-yl)ethan-1-one
CAS 1179611-54-1C9H14N4O2
2-(4-Amino-3-methylpyrazol-1-yl)-1-morpholin-4-ylethanone chemical structure, C10H16N4O2, CAS 1257553-54-0
2-(4-Amino-3-methylpyrazol-1-yl)-1-morpholin-4-ylethanone
CAS 1257553-54-0C10H16N4O2
2-(4-Iodopyrazol-1-yl)-1-morpholin-4-yl-ethanone chemical structure, C9H12IN3O2, CAS 1436205-29-6
2-(4-Iodopyrazol-1-yl)-1-morpholin-4-yl-ethanone
CAS 1436205-29-6C9H12IN3O2
4-(2-(1H-Pyrazol-1-yl)acetyl)morpholine-3-carboxylic acid chemical structure, C10H13N3O4, CAS 1466273-43-7
4-(2-(1H-Pyrazol-1-yl)acetyl)morpholine-3-carboxylic acid
CAS 1466273-43-7C10H13N3O4
Ethyl 3-tert-butyl-1-(2-morpholino-2-oxoethyl)-1H-pyrazole-5-carboxylate chemical structure, C16H25N3O4, CAS 1012880-30-6
Ethyl 3-tert-butyl-1-(2-morpholino-2-oxoethyl)-1H-pyrazole-5-carboxylate
CAS 1012880-30-6C16H25N3O4
1-(2-Morpholin-4-yl-2-oxoethyl)-1H-pyrazol-4-amine hydrochloride chemical structure, C9H15ClN4O2, CAS 1431967-90-6
1-(2-Morpholin-4-yl-2-oxoethyl)-1H-pyrazol-4-amine hydrochloride
CAS 1431967-90-6C9H15ClN4O2
2-(3-Bromo-1H-pyrazol-1-yl)-1-morpholinoethan-1-one chemical structure, C9H12BrN3O2, CAS 1427013-63-5
2-(3-Bromo-1H-pyrazol-1-yl)-1-morpholinoethan-1-one
CAS 1427013-63-5C9H12BrN3O2
2-(4-Hydroxy-1H-pyrazol-1-yl)-1-morpholinopropan-1-one chemical structure, C10H15N3O3, CAS 2906489-25-4
2-(4-Hydroxy-1H-pyrazol-1-yl)-1-morpholinopropan-1-one
CAS 2906489-25-4C10H15N3O3