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Murcko scaffold

Piperazine, 1-(4-oxo-4-phenylbutyl)-4-[(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)carbonyl]- scaffold

3 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
3
With full pages
0
Scaffold SMILES

O=C1CCc2cc(C(=O)N3CCN(CCCC(=O)c4ccccc4)CC3)ccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Piperazine, 1-(4-oxo-4-phenylbutyl)-4-[(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)carbonyl]- page
Murcko scaffold O=C1CCc2cc(C(=O)N3CCN(CCCC(=O)c4ccccc4)CC3)ccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

Piperazine, 1-(4-oxo-4-phenylbutyl)-4-[(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)carbonyl]- chemical structure, C24H27N3O3, CAS 106752-32-3
Piperazine, 1-(4-oxo-4-phenylbutyl)-4-[(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)carbonyl]-
CAS 106752-32-3C24H27N3O3
2(1H)-Quinolinone, 3,4-dihydro-6-((4-(4-oxo-4-phenylbutyl)-1-piperazinyl)carbonyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) chemical structure, C30H35N3O10, CAS 123941-50-4
2(1H)-Quinolinone, 3,4-dihydro-6-((4-(4-oxo-4-phenylbutyl)-1-piperazinyl)carbonyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
CAS 123941-50-4C30H35N3O10
Orb2567331 chemical structure, C24H28ClN3O3, CAS 83735-19-7
Orb2567331
CAS 83735-19-7C24H28ClN3O3