CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 34 atoms

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
34
Chemicals
10
With full pages
0
Scaffold SMILES

O=c1ccn(C2CCC(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=S)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2CCC(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=S)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-MOE 2-Thio-U amidite chemical structure, C42H53N4O9PS, CAS 647839-25-6
2-MOE 2-Thio-U amidite
CAS 647839-25-6C42H53N4O9PS
Orb1907701 chemical structure, C31H32N2O7S, CAS 302918-83-8
Orb1907701
CAS 302918-83-8C31H32N2O7S
2 inverted exclamation mark-O-Me-2-thio-U-3 inverted exclamation mark-phos phoramidite chemical structure, C40H49N4O8PS, CAS 302918-84-9
2 inverted exclamation mark-O-Me-2-thio-U-3 inverted exclamation mark-phos phoramidite
CAS 302918-84-9C40H49N4O8PS
1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C31H32N2O6S, CAS 125258-60-8
1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 125258-60-8C31H32N2O6S
3-[[(2R,3S,5R)-2-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(5-methyl-4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile chemical structure, C40H49N4O7PS, CAS 125258-63-1
3-[[(2R,3S,5R)-2-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(5-methyl-4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
CAS 125258-63-1C40H49N4O7PS
1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C30H30N2O7S, CAS 163496-06-8
1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 163496-06-8C30H30N2O7S
2-F 2-Thio-T amidite chemical structure, C40H48FN4O7PS, CAS 607353-03-7
2-F 2-Thio-T amidite
CAS 607353-03-7C40H48FN4O7PS
Orb1907699 chemical structure, C39H47N4O7PS, CAS 152753-94-1
Orb1907699
CAS 152753-94-1C39H47N4O7PS
2-OTBS 2-Thio-U amidite chemical structure, C45H61N4O8PSSi, CAS 163496-21-7
2-OTBS 2-Thio-U amidite
CAS 163496-21-7C45H61N4O8PSSi
3-[[(2R,3R,4R,5R)-2-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-(5-methyl-4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile chemical structure, C41H51N4O8PS, CAS 1350852-12-8
3-[[(2R,3R,4R,5R)-2-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-(5-methyl-4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
CAS 1350852-12-8C41H51N4O8PS