CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 13 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
22
With full pages
6
Scaffold SMILES

c1ccc(CSc2nnco2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2nnco2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

Simetryn, mixted with benoxazole chemical structure, C20H28ClN7OS2, CAS 39442-41-6
Simetryn, mixted with benoxazole
CAS 39442-41-6C20H28ClN7OS2
2-(((2-Chlorophenyl)methyl)thio)-5-propyl-1,3,4-oxadiazole chemical structure, C12H13ClN2OS, CAS 28923-80-0
2-(((2-Chlorophenyl)methyl)thio)-5-propyl-1,3,4-oxadiazole
CAS 28923-80-0C12H13ClN2OS
2-(5-((2,4-Dichlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)ethanamine chemical structure, C11H11Cl2N3OS, CAS 840498-30-8
2-(5-((2,4-Dichlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)ethanamine
CAS 840498-30-8C11H11Cl2N3OS
tert-Butyl 2-{5-[(2-methylbenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}ethylcarbamate chemical structure, C17H23N3O3S, CAS 840512-73-4
tert-Butyl 2-{5-[(2-methylbenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}ethylcarbamate
CAS 840512-73-4C17H23N3O3S
tert-Butyl N-[2-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)ethyl]carbamate chemical structure, C16H21N3O3S, CAS 840512-92-7
tert-Butyl N-[2-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)ethyl]carbamate
CAS 840512-92-7C16H21N3O3S
tert-Butyl N-[2-[5-[(4-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamate chemical structure, C17H23N3O3S, CAS 842973-17-5
tert-Butyl N-[2-[5-[(4-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamate
CAS 842973-17-5C17H23N3O3S
(1S)-3-Methyl-1-{5-[(4-methylbenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}butan-1-amine chemical structure, C15H21N3OS, CAS 1173670-57-9
(1S)-3-Methyl-1-{5-[(4-methylbenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}butan-1-amine
CAS 1173670-57-9C15H21N3OS
(1S)-1-{5-[(2,6-Dichlorobenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}ethanamine chemical structure, C11H11Cl2N3OS, CAS 1049978-44-0
(1S)-1-{5-[(2,6-Dichlorobenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}ethanamine
CAS 1049978-44-0C11H11Cl2N3OS
tert-Butyl N-[5-[5-[(3-fluorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]pentyl]carbamate chemical structure, C19H26FN3O3S, CAS 573944-27-1
tert-Butyl N-[5-[5-[(3-fluorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]pentyl]carbamate
CAS 573944-27-1C19H26FN3O3S
tert-Butyl N-[5-[5-[(2-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]pentyl]carbamate chemical structure, C20H29N3O3S, CAS 577997-02-5
tert-Butyl N-[5-[5-[(2-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]pentyl]carbamate
CAS 577997-02-5C20H29N3O3S
tert-Butyl N-[5-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)pentyl]carbamate chemical structure, C19H27N3O3S, CAS 575470-30-3
tert-Butyl N-[5-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)pentyl]carbamate
CAS 575470-30-3C19H27N3O3S
tert-Butyl N-[5-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]pentyl]carbamate chemical structure, C20H29N3O3S, CAS 575461-90-4
tert-Butyl N-[5-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]pentyl]carbamate
CAS 575461-90-4C20H29N3O3S
tert-Butyl N-[(1S,2R)-1-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-methylbutyl]carbamate chemical structure, C19H27N3O3S, CAS 1330750-52-1
tert-Butyl N-[(1S,2R)-1-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-methylbutyl]carbamate
CAS 1330750-52-1C19H27N3O3S
(S)-tert-Butyl (3-methyl-1-(5-((3-methylbenzyl)thio)-1,3,4-oxadiazol-2-yl)butyl)carbamate chemical structure, C20H29N3O3S, CAS 1173676-05-5
(S)-tert-Butyl (3-methyl-1-(5-((3-methylbenzyl)thio)-1,3,4-oxadiazol-2-yl)butyl)carbamate
CAS 1173676-05-5C20H29N3O3S
tert-Butyl N-[2-[5-[(3-chlorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamate chemical structure, C16H20ClN3O3S, CAS 577765-09-4
tert-Butyl N-[2-[5-[(3-chlorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamate
CAS 577765-09-4C16H20ClN3O3S
4-[[5-(Methoxymethyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]benzonitrile chemical structure, C12H11N3O2S, CAS 6696-82-8
4-[[5-(Methoxymethyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]benzonitrile
CAS 6696-82-8C12H11N3O2S
2-[(5-Ethyl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]benzonitrile chemical structure, C12H11N3OS, CAS 892679-19-5
2-[(5-Ethyl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]benzonitrile
CAS 892679-19-5C12H11N3OS
2-(Benzylsulfanyl)-5-methyl-1,3,4-oxadiazole chemical structure, C10H10N2OS, CAS 28915-24-4
2-(Benzylsulfanyl)-5-methyl-1,3,4-oxadiazole
CAS 28915-24-4C10H10N2OS
1,3,4-Oxadiazole-2-propanamine, 5-[[(4-chlorophenyl)methyl]thio]- chemical structure, C12H14ClN3OS, CAS 928000-65-1
1,3,4-Oxadiazole-2-propanamine, 5-[[(4-chlorophenyl)methyl]thio]-
CAS 928000-65-1C12H14ClN3OS
3-Fluoro-4-(((5-methyl-1,3,4-oxadiazol-2-yl)thio)methyl)benzonitrile chemical structure, C11H8FN3OS, CAS 1030763-58-6
3-Fluoro-4-(((5-methyl-1,3,4-oxadiazol-2-yl)thio)methyl)benzonitrile
CAS 1030763-58-6C11H8FN3OS
Cambridge id 7116659 chemical structure, C10H10N4O4S, CAS 690684-01-6
Cambridge id 7116659
CAS 690684-01-6C10H10N4O4S
2-{[(4-Ethenylphenyl)methyl]sulfanyl}-5-heptyl-1,3,4-oxadiazole chemical structure, C18H24N2OS, CAS 866623-20-3
2-{[(4-Ethenylphenyl)methyl]sulfanyl}-5-heptyl-1,3,4-oxadiazole
CAS 866623-20-3C18H24N2OS