Murcko scaffold
Cyclopropylbenzene scaffold
19,216 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 19,216
- With full pages
- 39
Scaffold SMILES
c1ccc(C2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 961 to 1,008 of 19,216 chemicals
Methyl 1-(2-fluorophenyl)cyclopropane-1-carboxylate
CAS 943111-99-7C11H11FO2
5-Chloro-2-cyclopropylaniline
CAS 104902-30-9C9H10ClN
![2,2-Dimethyl-3-[4-(trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid chemical structure, C13H13F3O3, CAS 85374-03-4](/s/ZRZBQMMBEFMMBO-UHFFFAOYSA-N.svg)
2,2-Dimethyl-3-[4-(trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid
CAS 85374-03-4C13H13F3O3
![[1-(4-tert-Butylphenyl)cyclopropyl]methanol chemical structure, C14H20O, CAS 95266-20-9](/s/VKMFVOOSVXRHQM-UHFFFAOYSA-N.svg)
[1-(4-tert-Butylphenyl)cyclopropyl]methanol
CAS 95266-20-9C14H20O
![[1-(4-Ethylphenyl)cyclopropyl]methanol chemical structure, C12H16O, CAS 1780456-57-6](/s/IZLINENTYKTHGJ-UHFFFAOYSA-N.svg)
[1-(4-Ethylphenyl)cyclopropyl]methanol
CAS 1780456-57-6C12H16O
(1-(4-Bromophenyl)cyclopropyl)methanol
CAS 98480-31-0C10H11BrO
![{1-[4-(Difluoromethoxy)phenyl]cyclopropyl}methanol chemical structure, C11H12F2O2, CAS 95899-64-2](/s/CVIKVKARIZHODN-UHFFFAOYSA-N.svg)
{1-[4-(Difluoromethoxy)phenyl]cyclopropyl}methanol
CAS 95899-64-2C11H12F2O2
1-(3-Chlorophenyl)cyclopropanemethanol
CAS 98480-33-2C10H11ClO
![{1-[4-(Propan-2-yloxy)phenyl]cyclopropyl}methanol chemical structure, C13H18O2, CAS 144785-90-0](/s/BFCJIHOPNJCEKM-UHFFFAOYSA-N.svg)
{1-[4-(Propan-2-yloxy)phenyl]cyclopropyl}methanol
CAS 144785-90-0C13H18O2
![[1-(3,4-Dichlorophenyl)cyclopropyl]methanol chemical structure, C10H10Cl2O, CAS 1379317-27-7](/s/RVXSXVVZMQIILT-UHFFFAOYSA-N.svg)
[1-(3,4-Dichlorophenyl)cyclopropyl]methanol
CAS 1379317-27-7C10H10Cl2O
![[1-(4-Methylphenyl)cyclopropyl]methanol chemical structure, C11H14O, CAS 98480-35-4](/s/LKSHAZCGBYIWBR-UHFFFAOYSA-N.svg)
[1-(4-Methylphenyl)cyclopropyl]methanol
CAS 98480-35-4C11H14O
1-(2-Ethoxyphenyl)cyclopropane-1-carboxylic acid
CAS 74205-25-7C12H14O3
2-Bromo-4-cyclopropylaniline
CAS 1353857-13-2C9H10BrN
![[1-(Trifluoromethyl)cyclopropyl]benzene chemical structure, C10H9F3, CAS 883547-73-7](/s/RBZAHILDWCBKFX-UHFFFAOYSA-N.svg)
[1-(Trifluoromethyl)cyclopropyl]benzene
CAS 883547-73-7C10H9F3
2-(2,2-Dichloroethenyl)-3-phenylcyclopropane-1-carboxylic acid
CAS 63649-21-8C12H10Cl2O2
2-(4-Cyclopropylphenyl)propanoic acid
CAS 1895584-18-5C12H14O2
2-(4-Cyclopropylphenyl)acetic acid
CAS 40641-90-5C11H12O2
(2,2-Dichloro-1-ethylcyclopropyl)benzene
CAS 27998-43-2C11H12Cl2
1-(4-Ethoxyphenyl)-2,2-difluorocyclopropane-1-carboxylic acid
CAS 63935-55-7C12H12F2O3
2-(2-Nitrophenyl)cyclopropane-1-carboxylic acid
CAS 1157642-41-5C10H9NO4
2,2-Dibromo-1-(4-ethoxyphenyl)cyclopropane-1-carboxylic acid
CAS 63935-28-4C12H12Br2O3
1-(4-Ethoxyphenyl)-2,2-dimethylcyclopropane-1-carboxylic acid
CAS 63935-54-6C14H18O3
4-(1-Ethylcyclopropyl)phenol
CAS 2138069-88-0C11H14O
![1-[1-(4-Chlorophenyl)cyclopropyl]ethan-1-one chemical structure, C11H11ClO, CAS 1017388-59-8](/s/ASFHBXWIBSPACX-UHFFFAOYSA-N.svg)
1-[1-(4-Chlorophenyl)cyclopropyl]ethan-1-one
CAS 1017388-59-8C11H11ClO
- rac-(1R,2R)-2-(3-Fluorophenyl)cyclopropane-1-carboxylic acid175168-72-6C10H9FO2
- (2-(2-Ethylphenyl)cyclopropyl)methanol1517037-41-0C12H16O
- rac-(1R,2R)-2-(2-Chlorophenyl)cyclopropane-1-carboxylic acid701914-00-3C10H9ClO2
- rac-(1R,2R)-2-(3,4-Dichlorophenyl)cyclopropane-1-carboxylic acid842119-90-8C10H8Cl2O2
- trans-2-(3,5-Difluorophenyl)cyclopropane-1-carboxylic acid705250-91-5C10H8F2O2
- (1R,2R)-2-(3,5-Dimethoxyphenyl)cyclopropane-1-carboxylic acid220352-05-6C12H14O4
- (1R,2R)-2-(3-Fluoro-4-methoxy-phenyl)cyclopropanecarboxylic acid1609290-12-1C11H11FO3
- rac-(1R,2R)-2-(3-Methoxy-4-methylphenyl)cyclopropane-1-carboxylic acid220352-77-2C12H14O3
- Rac-(1r,2r)-2-(3-methylphenyl)cyclopropane-1-carboxylic acid243665-19-2C11H12O2
- rac-(1R,2R)-2-(3-Nitrophenyl)cyclopropane-1-carboxylic acid115977-28-1C10H9NO4
- rac-(1R,2R)-2-[4-(Propan-2-yloxy)phenyl]cyclopropane-1-carboxylic acid1258784-76-7C13H16O3
- rac-(1R,2R)-2-(4-Methoxy-3-methylphenyl)cyclopropane-1-carboxylic acid1257122-69-2C12H14O3
- 4-[(1S,2R)-2-Aminocyclopropyl]-N,N-dimethylaniline1808068-61-2C11H16N2
- rel-(1R,2R)-2-(4-(Dimethylamino)phenyl)cyclopropanecarboxylic acid2307771-93-1C12H15NO2
- tert-Butyl 1-(4-iodophenyl)cyclopropane-1-carboxylate228410-33-1C14H17IO2
- Methyl 1-(4-hydroxyphenyl)cyclopropane-1-carboxylate779199-69-8C11H12O3
- 2-(3-Chlorophenyl)-N-methoxy-N-methylcyclopropanecarboxamide701914-02-5C12H14ClNO2
- 3-(3-Bromo-4-fluoro-phenyl)-2,2-dimethyl-cyclopropanecarboxylic acid1487985-44-3C12H12BrFO2
- 3-(3-Chloro-4-fluorophenyl)-2,2-dimethylcyclopropane-1-carboxylic acid1700274-92-5C12H12ClFO2
- 3-(3-Chlorophenyl)-2,2-dimethylcyclopropane-1-carboxylic acid1267089-68-8C12H13ClO2
- 1-(3-Bromo-4-fluorophenyl)cyclopropan-1-ol929884-51-5C9H8BrFO
- [2-(4-Methoxyphenyl)cyclopropyl]methanol1352898-22-6C11H14O2
- 1-(3-Fluorophenyl)cyclopropan-1-amine764647-70-3C9H10FN
- 1-[4-(2-Methylpropyl)phenyl]cyclopropane-1-carboxylic acid41315-13-3C14H18O2
Related scaffolds
Same ring framework with different atoms or bond orders
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c1cc(C2CC2)ncn12 chemicals
O=C1OCCC=C1C1CO11 chemical
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c1ncnc(C2CC2)n11 chemical
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