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Murcko scaffold

Ring system with 4 rings and 24 atoms

28 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
28
With full pages
4
Scaffold SMILES

O=C(NC(=S)Nc1ccc2c3c(cccc13)CC2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC(=S)Nc1ccc2c3c(cccc13)CC2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-methylbenzamide chemical structure, C21H18N2OS, CAS 6427-34-5
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-methylbenzamide
CAS 6427-34-5C21H18N2OS
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-methylbenzamide chemical structure, C21H18N2OS, CAS 333740-57-1
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-methylbenzamide
CAS 333740-57-1C21H18N2OS
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3-methylbenzamide chemical structure, C21H18N2OS, CAS 356076-89-6
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3-methylbenzamide
CAS 356076-89-6C21H18N2OS
3,4-Dichloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide chemical structure, C20H14Cl2N2OS, CAS 445416-84-2
3,4-Dichloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide
CAS 445416-84-2C20H14Cl2N2OS
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3-methoxybenzamide chemical structure, C21H18N2O2S, CAS 430453-78-4
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3-methoxybenzamide
CAS 430453-78-4C21H18N2O2S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-nitrobenzamide chemical structure, C20H15N3O3S, CAS 335210-05-4
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-nitrobenzamide
CAS 335210-05-4C20H15N3O3S
1-Acenaphthen-5-yl-3-(3,4-dimethoxy-benzoyl)-thiourea chemical structure, C22H20N2O3S, CAS 335213-76-8
1-Acenaphthen-5-yl-3-(3,4-dimethoxy-benzoyl)-thiourea
CAS 335213-76-8C22H20N2O3S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3,4,5-trimethoxybenzamide chemical structure, C23H22N2O4S, CAS 380307-69-7
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3,4,5-trimethoxybenzamide
CAS 380307-69-7C23H22N2O4S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-methoxybenzamide chemical structure, C21H18N2O2S, CAS 333739-75-6
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-methoxybenzamide
CAS 333739-75-6C21H18N2O2S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-methoxybenzamide chemical structure, C21H18N2O2S, CAS 333741-30-3
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-methoxybenzamide
CAS 333741-30-3C21H18N2O2S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3,5-dimethoxybenzamide chemical structure, C22H20N2O3S, CAS 430444-52-3
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3,5-dimethoxybenzamide
CAS 430444-52-3C22H20N2O3S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3-iodobenzamide chemical structure, C20H15IN2OS, CAS 425679-73-8
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3-iodobenzamide
CAS 425679-73-8C20H15IN2OS
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-fluorobenzamide chemical structure, C20H15FN2OS, CAS 425683-08-5
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-fluorobenzamide
CAS 425683-08-5C20H15FN2OS
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-propan-2-yloxybenzamide chemical structure, C23H22N2O2S, CAS 426217-28-9
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-propan-2-yloxybenzamide
CAS 426217-28-9C23H22N2O2S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-ethoxy-3-nitrobenzamide chemical structure, C22H19N3O4S, CAS 355430-87-4
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-4-ethoxy-3-nitrobenzamide
CAS 355430-87-4C22H19N3O4S
3-Chloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)-4-ethoxybenzamide chemical structure, C22H19ClN2O2S, CAS 428464-43-1
3-Chloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)-4-ethoxybenzamide
CAS 428464-43-1C22H19ClN2O2S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3,4,5-triethoxybenzamide chemical structure, C26H28N2O4S, CAS 355432-31-4
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-3,4,5-triethoxybenzamide
CAS 355432-31-4C26H28N2O4S
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-nitrobenzamide chemical structure, C20H15N3O3S, CAS 401618-68-6
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-nitrobenzamide
CAS 401618-68-6C20H15N3O3S
5-Bromo-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)-2-methoxybenzamide chemical structure, C21H17BrN2O2S, CAS 428485-29-4
5-Bromo-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)-2-methoxybenzamide
CAS 428485-29-4C21H17BrN2O2S
2,4-Dichloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide chemical structure, C20H14Cl2N2OS, CAS 428849-70-1
2,4-Dichloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide
CAS 428849-70-1C20H14Cl2N2OS
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-methyl-3-nitrobenzamide chemical structure, C21H17N3O3S, CAS 430443-63-3
N-(1,2-Dihydroacenaphthylen-5-ylcarbamothioyl)-2-methyl-3-nitrobenzamide
CAS 430443-63-3C21H17N3O3S
3-Chloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide chemical structure, C20H15ClN2OS, CAS 347327-05-3
3-Chloro-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide
CAS 347327-05-3C20H15ClN2OS
4-tert-Butyl-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide chemical structure, C24H24N2OS, CAS 428840-39-5
4-tert-Butyl-N-(1,2-dihydroacenaphthylen-5-ylcarbamothioyl)benzamide
CAS 428840-39-5C24H24N2OS
RefChem:382122 chemical structure, C20H15FN2OS, CAS 6406-96-8
RefChem:382122
CAS 6406-96-8C20H15FN2OS