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Murcko scaffold

2-(Benzimidazol-1-yl)-1-morpholin-4-ylethanone scaffold

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
21
With full pages
3
Scaffold SMILES

O=C(Cn1cnc2ccccc21)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Benzimidazol-1-yl)-1-morpholin-4-ylethanone page
Murcko scaffold O=C(Cn1cnc2ccccc21)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

2-(2-Ethylsulfanylbenzimidazol-1-yl)-1-morpholin-4-ylethanone chemical structure, C15H19N3O2S, CAS 341941-81-9
2-(2-Ethylsulfanylbenzimidazol-1-yl)-1-morpholin-4-ylethanone
CAS 341941-81-9C15H19N3O2S
2-(2-(Hydroxymethyl)-1H-benzo[d]imidazol-1-yl)-1-morpholinoethanone chemical structure, C14H17N3O3, CAS 361998-66-5
2-(2-(Hydroxymethyl)-1H-benzo[d]imidazol-1-yl)-1-morpholinoethanone
CAS 361998-66-5C14H17N3O3
2-(Ethylsulfonyl)-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-benzimidazole chemical structure, C15H19N3O4S, CAS 696606-66-3
2-(Ethylsulfonyl)-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-benzimidazole
CAS 696606-66-3C15H19N3O4S
1-Morpholino-2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]-1-ethanone chemical structure, C14H14F3N3O2, CAS 478048-17-8
1-Morpholino-2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]-1-ethanone
CAS 478048-17-8C14H14F3N3O2
2-({1-[2-(4-Morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)acetamide chemical structure, C15H18N4O3S, CAS 606110-53-6
2-({1-[2-(4-Morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)acetamide
CAS 606110-53-6C15H18N4O3S
N-tert-Butyl-2-[1-(2-morpholin-4-yl-2-oxoethyl)benzimidazol-2-yl]sulfanylacetamide chemical structure, C19H26N4O3S, CAS 606110-55-8
N-tert-Butyl-2-[1-(2-morpholin-4-yl-2-oxoethyl)benzimidazol-2-yl]sulfanylacetamide
CAS 606110-55-8C19H26N4O3S
Methyl ({1-[2-(4-morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)acetate chemical structure, C16H19N3O4S, CAS 606110-73-0
Methyl ({1-[2-(4-morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)acetate
CAS 606110-73-0C16H19N3O4S
({1-[2-(4-Morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)acetic acid chemical structure, C15H17N3O4S, CAS 606110-75-2
({1-[2-(4-Morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)acetic acid
CAS 606110-75-2C15H17N3O4S
Propan-2-yl 2-[1-(2-morpholin-4-yl-2-oxoethyl)benzimidazol-2-yl]sulfanylacetate chemical structure, C18H23N3O4S, CAS 606110-77-4
Propan-2-yl 2-[1-(2-morpholin-4-yl-2-oxoethyl)benzimidazol-2-yl]sulfanylacetate
CAS 606110-77-4C18H23N3O4S
2-({1-[2-(4-Morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)-N-propylacetamide chemical structure, C18H24N4O3S, CAS 606110-82-1
2-({1-[2-(4-Morpholinyl)-2-oxoethyl]-1H-benzimidazol-2-yl}sulfanyl)-N-propylacetamide
CAS 606110-82-1C18H24N4O3S
Acetamide,N,N-dimethyl-2-[[1-[2-(4-morpholinyl)-2-oxoethyl]-1H-benzo[D]imidazol-2-yl]thio]- chemical structure, C17H22N4O3S, CAS 606110-86-5
Acetamide,N,N-dimethyl-2-[[1-[2-(4-morpholinyl)-2-oxoethyl]-1H-benzo[D]imidazol-2-yl]thio]-
CAS 606110-86-5C17H22N4O3S
1-(2,6-Dimethylmorpholino)-2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]-1-ethanone chemical structure, C16H18F3N3O2, CAS 866018-02-2
1-(2,6-Dimethylmorpholino)-2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]-1-ethanone
CAS 866018-02-2C16H18F3N3O2
2-(2-Methylsulfonylbenzimidazol-1-yl)-1-morpholin-4-ylethanone chemical structure, C14H17N3O4S, CAS 344898-20-0
2-(2-Methylsulfonylbenzimidazol-1-yl)-1-morpholin-4-ylethanone
CAS 344898-20-0C14H17N3O4S
2-(Benzimidazol-1-yl)-1-morpholin-4-ylethanone chemical structure, C13H15N3O2, CAS 68242-84-2
2-(Benzimidazol-1-yl)-1-morpholin-4-ylethanone
CAS 68242-84-2C13H15N3O2
2-[2-(1-Hydroxypropyl)-1H-benzimidazol-1-yl]-1-(morpholin-4-yl)ethanone chemical structure, C16H21N3O3, CAS 890640-91-2
2-[2-(1-Hydroxypropyl)-1H-benzimidazol-1-yl]-1-(morpholin-4-yl)ethanone
CAS 890640-91-2C16H21N3O3
1-Morpholino-2-(2-(propylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone chemical structure, C16H21N3O4S, CAS 886904-28-5
1-Morpholino-2-(2-(propylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone
CAS 886904-28-5C16H21N3O4S
Methyl methyl((1-(2-morpholino-2-oxoethyl)-1H-benzo[d]imidazol-2-yl)methyl)carbamate chemical structure, C17H22N4O4, CAS 941962-48-7
Methyl methyl((1-(2-morpholino-2-oxoethyl)-1H-benzo[d]imidazol-2-yl)methyl)carbamate
CAS 941962-48-7C17H22N4O4
2-[2-(2-Hydroxyethyl)-1H-benzimidazol-1-yl]-1-(morpholin-4-yl)ethanone chemical structure, C15H19N3O3, CAS 929857-47-6
2-[2-(2-Hydroxyethyl)-1H-benzimidazol-1-yl]-1-(morpholin-4-yl)ethanone
CAS 929857-47-6C15H19N3O3
1-(2,6-Dimethylmorpholino)-2-(2-(methylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone chemical structure, C16H21N3O4S, CAS 886923-09-7
1-(2,6-Dimethylmorpholino)-2-(2-(methylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone
CAS 886923-09-7C16H21N3O4S
1-(2,6-Dimethylmorpholino)-2-(2-(ethylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone chemical structure, C17H23N3O4S, CAS 886924-53-4
1-(2,6-Dimethylmorpholino)-2-(2-(ethylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone
CAS 886924-53-4C17H23N3O4S
1-(2,6-Dimethylmorpholino)-2-(2-(propylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone chemical structure, C18H25N3O4S, CAS 886905-24-4
1-(2,6-Dimethylmorpholino)-2-(2-(propylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone
CAS 886905-24-4C18H25N3O4S