CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

166 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
166
With full pages
15
Scaffold SMILES

O=C(Nc1ccccc1)c1csc2c1CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1csc2c1CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 166 chemicals

2-Amino-N-(3,4-dimethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C17H20N2OS, CAS 312505-88-7
2-Amino-N-(3,4-dimethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 312505-88-7C17H20N2OS
2-Amino-N-(3,5-dimethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C17H20N2OS, CAS 312506-96-0
2-Amino-N-(3,5-dimethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 312506-96-0C17H20N2OS
N-Phenyl-2-(propanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C18H20N2O2S, CAS 312946-57-9
N-Phenyl-2-(propanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 312946-57-9C18H20N2O2S
2-Amino-N-(2-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H18N2OS, CAS 62349-29-5
2-Amino-N-(2-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 62349-29-5C16H18N2OS
2-Amino-N-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H18N2O2S, CAS 83822-33-7
2-Amino-N-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 83822-33-7C16H18N2O2S
2-Amino-N-(2-ethoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C17H20N2O2S, CAS 329069-00-3
2-Amino-N-(2-ethoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 329069-00-3C17H20N2O2S
N-(4-Cyanophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H14N2OS, CAS 314250-92-5
N-(4-Cyanophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 314250-92-5C16H14N2OS
N-(4-Chlorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H14ClNOS, CAS 314250-88-9
N-(4-Chlorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 314250-88-9C15H14ClNOS
2-Acetamido-N-(2-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C18H20N2O2S, CAS 62349-31-9
2-Acetamido-N-(2-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 62349-31-9C18H20N2O2S
N-(2-Methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H17NO2S, CAS 314250-81-2
N-(2-Methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 314250-81-2C16H17NO2S
N-(3-Bromophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H14BrNOS, CAS 314250-94-7
N-(3-Bromophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 314250-94-7C15H14BrNOS
N-(4-Bromophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H14BrNOS, CAS 314250-95-8
N-(4-Bromophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 314250-95-8C15H14BrNOS
N-(2-Bromophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H14BrNOS, CAS 314250-93-6
N-(2-Bromophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 314250-93-6C15H14BrNOS
2-Amino-N-(4-chlorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H15ClN2OS, CAS 69438-16-0
2-Amino-N-(4-chlorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 69438-16-0C15H15ClN2OS
2-Amino-N-(3-chlorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H15ClN2OS, CAS 85930-58-1
2-Amino-N-(3-chlorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 85930-58-1C15H15ClN2OS
N-(2-Hydroxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H15NO2S, CAS 332916-42-4
N-(2-Hydroxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 332916-42-4C15H15NO2S
N-(4-Ethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C17H19NOS, CAS 618393-96-7
N-(4-Ethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 618393-96-7C17H19NOS
N-(2-Fluoro-5-nitrophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H13FN2O3S, CAS 514816-56-9
N-(2-Fluoro-5-nitrophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 514816-56-9C15H13FN2O3S
N-(5-Chloro-2-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H16ClNOS, CAS 445022-86-6
N-(5-Chloro-2-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 445022-86-6C16H16ClNOS
2-Amino-N-(4-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H18N2OS, CAS 83822-35-9
2-Amino-N-(4-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 83822-35-9C16H18N2OS
N-(3-Nitrophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H14N2O3S, CAS 314250-84-5
N-(3-Nitrophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 314250-84-5C15H14N2O3S
2-(4,5,6,7-Tetrahydrobenzo[b]thiophene-3-carboxamido)benzoic acid chemical structure, C16H15NO3S, CAS 683267-43-8
2-(4,5,6,7-Tetrahydrobenzo[b]thiophene-3-carboxamido)benzoic acid
CAS 683267-43-8C16H15NO3S
N-(2,4-Dimethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C17H19NOS, CAS 618394-08-4
N-(2,4-Dimethylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 618394-08-4C17H19NOS
2-Amino-N-phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C15H16N2OS, CAS 60598-68-7
2-Amino-N-phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 60598-68-7C15H16N2OS