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Murcko scaffold

Ring system with 2 rings and 9 atoms

51 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
51
With full pages
3
Scaffold SMILES

c1scc2c1CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1scc2c1CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 51 chemicals

4,5,6,7-Tetrahydro-2-benzothiophene-1-carboxylic acid chemical structure, C9H10O2S, CAS 6435-75-2
4,5,6,7-Tetrahydro-2-benzothiophene-1-carboxylic acid
CAS 6435-75-2C9H10O2S
Ethyl 4-hydroxy-3-(methylsulfanyl)-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylate chemical structure, C12H16O3S2, CAS 172516-36-8
Ethyl 4-hydroxy-3-(methylsulfanyl)-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylate
CAS 172516-36-8C12H16O3S2
4-Hydroxy-3-methylsulfanyl-4,5,6,7-tetrahydro-2-benzothiophene-1-carbonitrile chemical structure, C10H11NOS2, CAS 882260-92-6
4-Hydroxy-3-methylsulfanyl-4,5,6,7-tetrahydro-2-benzothiophene-1-carbonitrile
CAS 882260-92-6C10H11NOS2
4-Hydroxy-3-methylsulfanyl-4,5,6,7-tetrahydro-2-benzothiophene-1-carbohydrazide chemical structure, C10H14N2O2S2, CAS 172516-38-0
4-Hydroxy-3-methylsulfanyl-4,5,6,7-tetrahydro-2-benzothiophene-1-carbohydrazide
CAS 172516-38-0C10H14N2O2S2
Methyl 3-bromo-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylate chemical structure, C10H11BrO2S, CAS 188240-62-2
Methyl 3-bromo-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylate
CAS 188240-62-2C10H11BrO2S
Methyl 4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate chemical structure, C10H12O2S, CAS 6435-72-9
Methyl 4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate
CAS 6435-72-9C10H12O2S
3-Bromo-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylic acid chemical structure, C9H9BrO2S, CAS 188240-63-3
3-Bromo-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylic acid
CAS 188240-63-3C9H9BrO2S
1-(Methylsulfanyl)-4,5,6,7-tetrahydro-2-benzothiophene chemical structure, C9H12S2, CAS 125150-88-1
1-(Methylsulfanyl)-4,5,6,7-tetrahydro-2-benzothiophene
CAS 125150-88-1C9H12S2
3-Ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid chemical structure, C13H18O2S, CAS 910635-45-9
3-Ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid
CAS 910635-45-9C13H18O2S
5,5-Dimethyl-3-propyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid chemical structure, C14H20O2S, CAS 910635-46-0
5,5-Dimethyl-3-propyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid
CAS 910635-46-0C14H20O2S
3-Formyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid chemical structure, C12H14O3S, CAS 910635-48-2
3-Formyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid
CAS 910635-48-2C12H14O3S
1-(3,5,5-Trimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C13H18OS, CAS 910635-58-4
1-(3,5,5-Trimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-58-4C13H18OS
1-(3-Ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C14H20OS, CAS 910635-60-8
1-(3-Ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-60-8C14H20OS
1-(5,5-Dimethyl-3-methylsulfanyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C13H18OS2, CAS 910635-61-9
1-(5,5-Dimethyl-3-methylsulfanyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-61-9C13H18OS2
3-Bromo-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester chemical structure, C13H17BrO2S, CAS 910635-63-1
3-Bromo-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester
CAS 910635-63-1C13H17BrO2S
3-Methoxy-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid chemical structure, C12H16O3S, CAS 910635-64-2
3-Methoxy-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid
CAS 910635-64-2C12H16O3S
1-(5,5-Diethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C14H20OS, CAS 910635-67-5
1-(5,5-Diethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-67-5C14H20OS
1-(3,5,5-Triethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C16H24OS, CAS 910635-69-7
1-(3,5,5-Triethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-69-7C16H24OS
1-(3-Ethyl-5-methyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C13H18OS, CAS 910635-75-5
1-(3-Ethyl-5-methyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-75-5C13H18OS
5-Ethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid chemical structure, C11H14O2S, CAS 910635-76-6
5-Ethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid
CAS 910635-76-6C11H14O2S
1-(5-Ethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C12H16OS, CAS 910635-77-7
1-(5-Ethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-77-7C12H16OS
2-Bromo-1-(3-ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone chemical structure, C14H19BrOS, CAS 910635-88-0
2-Bromo-1-(3-ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-ethanone
CAS 910635-88-0C14H19BrOS
5,5-Dimethyl-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylic acid chemical structure, C11H14O2S, CAS 910635-40-4
5,5-Dimethyl-4,5,6,7-tetrahydro-2-benzothiophene-1-carboxylic acid
CAS 910635-40-4C11H14O2S
5,5-Dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester chemical structure, C13H18O2S, CAS 910635-41-5
5,5-Dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester
CAS 910635-41-5C13H18O2S