CompoundList
Sign in
Murcko scaffold

Prot-IN-1 scaffold

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
9
With full pages
5
Scaffold SMILES

O=C(c1ccc(-c2ccccc2)cc1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Prot-IN-1 page
Murcko scaffold O=C(c1ccc(-c2ccccc2)cc1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Prot-IN-1 chemical structure, C23H22N2O, CAS 329935-45-7
Prot-IN-1
CAS 329935-45-7C23H22N2O
[4-(3-Chlorophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone chemical structure, C23H21ClN2O, CAS 329939-13-1
[4-(3-Chlorophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone
CAS 329939-13-1C23H21ClN2O
[4-(2-Ethoxyphenyl)piperazin-1-yl]-(4-phenylphenyl)methanone chemical structure, C25H26N2O2, CAS 560075-47-0
[4-(2-Ethoxyphenyl)piperazin-1-yl]-(4-phenylphenyl)methanone
CAS 560075-47-0C25H26N2O2
[4-(2-Methoxyphenyl)piperazin-1-yl]-(4-phenylphenyl)methanone chemical structure, C24H24N2O2, CAS 349407-18-7
[4-(2-Methoxyphenyl)piperazin-1-yl]-(4-phenylphenyl)methanone
CAS 349407-18-7C24H24N2O2
[4-(4-Fluorophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone chemical structure, C23H21FN2O, CAS 333350-74-6
[4-(4-Fluorophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone
CAS 333350-74-6C23H21FN2O
[4-(2-Fluorophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone chemical structure, C23H21FN2O, CAS 432529-33-4
[4-(2-Fluorophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone
CAS 432529-33-4C23H21FN2O
[4-(4-Nitrophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone chemical structure, C23H21N3O3, CAS 312703-89-2
[4-(4-Nitrophenyl)piperazin-1-yl]-(4-phenylphenyl)methanone
CAS 312703-89-2C23H21N3O3
[4-[2-Nitro-4-(trifluoromethyl)phenyl]piperazin-1-yl]-(4-phenylphenyl)methanone chemical structure, C24H20F3N3O3, CAS 425631-06-7
[4-[2-Nitro-4-(trifluoromethyl)phenyl]piperazin-1-yl]-(4-phenylphenyl)methanone
CAS 425631-06-7C24H20F3N3O3
(4-Phenylphenyl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone chemical structure, C24H21F3N2O, CAS 432526-19-7
(4-Phenylphenyl)-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
CAS 432526-19-7C24H21F3N2O