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Murcko scaffold

1-Benzylimidazolidine-2,4-dione scaffold

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
24
With full pages
4
Scaffold SMILES

O=C1CN(Cc2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzylimidazolidine-2,4-dione page
Murcko scaffold O=C1CN(Cc2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

Ethyl 3-benzyl-2,5-dioxoimidazolidine-4-carboxylate chemical structure, C13H14N2O4, CAS 56598-93-7
Ethyl 3-benzyl-2,5-dioxoimidazolidine-4-carboxylate
CAS 56598-93-7C13H14N2O4
Ethyl 3-benzyl-1-methyl-2,5-dioxoimidazolidine-4-carboxylate chemical structure, C14H16N2O4, CAS 56598-94-8
Ethyl 3-benzyl-1-methyl-2,5-dioxoimidazolidine-4-carboxylate
CAS 56598-94-8C14H16N2O4
1-Benzylimidazolidine-2,4-dione chemical structure, C10H10N2O2, CAS 6777-05-5
1-Benzylimidazolidine-2,4-dione
CAS 6777-05-5C10H10N2O2
2,4-Imidazolidinedione, 5-ethoxy-1-(phenylmethyl)- chemical structure, C12H14N2O3, CAS 65855-02-9
2,4-Imidazolidinedione, 5-ethoxy-1-(phenylmethyl)-
CAS 65855-02-9C12H14N2O3
3-Benzyl-2,5-dioxo-4,4-dimethylimidazolidine chemical structure, C12H14N2O2, CAS 3720-03-4
3-Benzyl-2,5-dioxo-4,4-dimethylimidazolidine
CAS 3720-03-4C12H14N2O2
1-Benzyl-5-hydroxyimidazolidine-2,4-dione chemical structure, C10H10N2O3, CAS 110668-56-9
1-Benzyl-5-hydroxyimidazolidine-2,4-dione
CAS 110668-56-9C10H10N2O3
1-Benzyl-5-(hexadecyloxy)imidazolidine-2,4-dione chemical structure, C26H42N2O3, CAS 158574-65-3
1-Benzyl-5-(hexadecyloxy)imidazolidine-2,4-dione
CAS 158574-65-3C26H42N2O3
1-(1-Phenylethyl)imidazolidine-2,4-dione chemical structure, C11H12N2O2, CAS 86095-58-1
1-(1-Phenylethyl)imidazolidine-2,4-dione
CAS 86095-58-1C11H12N2O2
5-Hydroxy-1-[(3-methoxyphenyl)methyl]imidazolidine-2,4-dione chemical structure, C11H12N2O4, CAS 92764-15-3
5-Hydroxy-1-[(3-methoxyphenyl)methyl]imidazolidine-2,4-dione
CAS 92764-15-3C11H12N2O4
1-[(2-Chlorophenyl)methyl]imidazolidine-2,4-dione chemical structure, C10H9ClN2O2, CAS 187243-31-8
1-[(2-Chlorophenyl)methyl]imidazolidine-2,4-dione
CAS 187243-31-8C10H9ClN2O2
1-[(2,6-Dichlorophenyl)methyl]imidazolidine-2,4-dione chemical structure, C10H8Cl2N2O2, CAS 187243-32-9
1-[(2,6-Dichlorophenyl)methyl]imidazolidine-2,4-dione
CAS 187243-32-9C10H8Cl2N2O2
1-(4-Bromobenzyl)imidazolidine-2,4-dione chemical structure, C10H9BrN2O2, CAS 201987-81-7
1-(4-Bromobenzyl)imidazolidine-2,4-dione
CAS 201987-81-7C10H9BrN2O2
2-(3-Benzyl-2,5-dioxoimidazolidin-4-yl)acetic acid chemical structure, C12H12N2O4, CAS 494866-98-7
2-(3-Benzyl-2,5-dioxoimidazolidin-4-yl)acetic acid
CAS 494866-98-7C12H12N2O4
1-[(4-Chlorophenyl)methyl]imidazolidine-2,4-dione chemical structure, C10H9ClN2O2, CAS 152146-73-1
1-[(4-Chlorophenyl)methyl]imidazolidine-2,4-dione
CAS 152146-73-1C10H9ClN2O2
5-(2-Aminoethoxy)-1-benzylimidazolidine-2,4-dione chemical structure, C12H15N3O3, CAS 90178-15-7
5-(2-Aminoethoxy)-1-benzylimidazolidine-2,4-dione
CAS 90178-15-7C12H15N3O3
1-[(4-Methoxyphenyl)methyl]imidazolidine-2,4-dione chemical structure, C11H12N2O3, CAS 652992-63-7
1-[(4-Methoxyphenyl)methyl]imidazolidine-2,4-dione
CAS 652992-63-7C11H12N2O3
1-(2-Bromobenzyl)imidazolidine-2,4-dione chemical structure, C10H9BrN2O2, CAS 1245646-01-8
1-(2-Bromobenzyl)imidazolidine-2,4-dione
CAS 1245646-01-8C10H9BrN2O2
1-(3-Bromobenzyl)imidazolidine-2,4-dione chemical structure, C10H9BrN2O2, CAS 1245647-33-9
1-(3-Bromobenzyl)imidazolidine-2,4-dione
CAS 1245647-33-9C10H9BrN2O2
1-(4-Bromobenzyl)-3-isopropylimidazolidine-2,4-dione chemical structure, C13H15BrN2O2, CAS 1228660-48-7
1-(4-Bromobenzyl)-3-isopropylimidazolidine-2,4-dione
CAS 1228660-48-7C13H15BrN2O2
1-(4-Bromobenzyl)-3-methylimidazolidine-2,4-dione chemical structure, C11H11BrN2O2, CAS 1228660-41-0
1-(4-Bromobenzyl)-3-methylimidazolidine-2,4-dione
CAS 1228660-41-0C11H11BrN2O2
3-Butyl-1-[(4-methoxyphenyl)methyl]imidazolidine-2,4-dione chemical structure, C15H20N2O3, CAS 662166-80-5
3-Butyl-1-[(4-methoxyphenyl)methyl]imidazolidine-2,4-dione
CAS 662166-80-5C15H20N2O3
1-[(4-Bromophenyl)methyl]-3-(2,2-difluoroethyl)imidazolidine-2,4-dione chemical structure, C12H11BrF2N2O2, CAS 1228594-53-3
1-[(4-Bromophenyl)methyl]-3-(2,2-difluoroethyl)imidazolidine-2,4-dione
CAS 1228594-53-3C12H11BrF2N2O2
1-[(3,5-Dichlorophenyl)methyl]imidazolidine-2,4-dione chemical structure, C10H8Cl2N2O2, CAS 2408971-25-3
1-[(3,5-Dichlorophenyl)methyl]imidazolidine-2,4-dione
CAS 2408971-25-3C10H8Cl2N2O2
3-(tert-Butyl)-5-ethyl-1-(4-methoxybenzyl)imidazolidine-2,4-dione chemical structure, C17H24N2O3, CAS 1802050-96-9
3-(tert-Butyl)-5-ethyl-1-(4-methoxybenzyl)imidazolidine-2,4-dione
CAS 1802050-96-9C17H24N2O3