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Murcko scaffold

Ring system with 2 rings and 18 atoms

61 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
61
With full pages
4
Scaffold SMILES

C=C(N=Nc1ccccc1)C(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C(N=Nc1ccccc1)C(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

3-(4-Bromophenyl)-3-oxo-2-{2-[4-(trifluoromethyl)phenyl]hydrazono}propanal chemical structure, C16H10BrF3N2O2, CAS 338414-09-8
3-(4-Bromophenyl)-3-oxo-2-{2-[4-(trifluoromethyl)phenyl]hydrazono}propanal
CAS 338414-09-8C16H10BrF3N2O2
(2E)-2-[2-(4-Methoxyphenyl)hydrazin-1-ylidene]-3-oxo-3-phenylpropanal chemical structure, C16H14N2O3, CAS 77083-67-1
(2E)-2-[2-(4-Methoxyphenyl)hydrazin-1-ylidene]-3-oxo-3-phenylpropanal
CAS 77083-67-1C16H14N2O3
3-(4-Methoxyphenyl)-3-oxo-2-{2-[4-(trifluoromethyl)phenyl]hydrazono}propanal chemical structure, C17H13F3N2O3, CAS 338414-11-2
3-(4-Methoxyphenyl)-3-oxo-2-{2-[4-(trifluoromethyl)phenyl]hydrazono}propanal
CAS 338414-11-2C17H13F3N2O3
(E)-1-(4-Chlorophenyl)-3-hydroxy-2-[(4-methylphenyl)diazenyl]prop-2-en-1-one chemical structure, C16H13ClN2O2
(E)-1-(4-Chlorophenyl)-3-hydroxy-2-[(4-methylphenyl)diazenyl]prop-2-en-1-one
C16H13ClN2O2
(2E)-2-[2-(4-Methoxyphenyl)hydrazin-1-ylidene]-3-oxo-3-phenylpropanal chemical structure, C16H14N2O3
(2E)-2-[2-(4-Methoxyphenyl)hydrazin-1-ylidene]-3-oxo-3-phenylpropanal
C16H14N2O3
3-Oxo-3-phenyl-2-(2-phenylhydrazono)propanal chemical structure, C15H12N2O2
3-Oxo-3-phenyl-2-(2-phenylhydrazono)propanal
C15H12N2O2
3-Oxo-3-phenyl-2-{2-[3-(trifluoromethyl)phenyl]hydrazono}propanal chemical structure, C16H11F3N2O2
3-Oxo-3-phenyl-2-{2-[3-(trifluoromethyl)phenyl]hydrazono}propanal
C16H11F3N2O2
3-(4-Chlorophenyl)-3-oxo-2-(2-phenylhydrazono)propanal chemical structure, C15H11ClN2O2
3-(4-Chlorophenyl)-3-oxo-2-(2-phenylhydrazono)propanal
C15H11ClN2O2
3-(4-Bromophenyl)-2-[2-(3-methylphenyl)hydrazono]-3-oxopropanal chemical structure, C16H13BrN2O2, CAS 338414-08-7
3-(4-Bromophenyl)-2-[2-(3-methylphenyl)hydrazono]-3-oxopropanal
CAS 338414-08-7C16H13BrN2O2
(2E)-3-Oxo-3-phenyl-2-(2-phenylhydrazin-1-ylidene)propanal chemical structure, C15H12N2O2, CAS 60083-18-3
(2E)-3-Oxo-3-phenyl-2-(2-phenylhydrazin-1-ylidene)propanal
CAS 60083-18-3C15H12N2O2
(2E)-3-(4-Methoxyphenyl)-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]-3-oxopropanal chemical structure, C17H16N2O4
(2E)-3-(4-Methoxyphenyl)-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]-3-oxopropanal
C17H16N2O4
3-(4-Chlorophenyl)-3-oxo-2-(phenylhydrazinylidene)propanal chemical structure, C15H11ClN2O2, CAS 337512-10-4
3-(4-Chlorophenyl)-3-oxo-2-(phenylhydrazinylidene)propanal
CAS 337512-10-4C15H11ClN2O2
3-(4-Chlorophenyl)-2-[2-(4-fluorophenyl)hydrazono]-3-oxopropanal chemical structure, C15H10ClFN2O2
3-(4-Chlorophenyl)-2-[2-(4-fluorophenyl)hydrazono]-3-oxopropanal
C15H10ClFN2O2
(2E)-3-(4-Chlorophenyl)-2-[2-(4-methylphenyl)hydrazin-1-ylidene]-3-oxopropanal chemical structure, C16H13ClN2O2
(2E)-3-(4-Chlorophenyl)-2-[2-(4-methylphenyl)hydrazin-1-ylidene]-3-oxopropanal
C16H13ClN2O2
(E)-2-[(4-Chlorophenyl)diazenyl]-3-hydroxy-1-phenylprop-2-en-1-one chemical structure, C15H11ClN2O2, CAS 40640-21-9
(E)-2-[(4-Chlorophenyl)diazenyl]-3-hydroxy-1-phenylprop-2-en-1-one
CAS 40640-21-9C15H11ClN2O2
(2E)-2-[2-(3,5-Dimethylphenyl)hydrazin-1-ylidene]-3-(4-methoxyphenyl)-3-oxopropanal chemical structure, C18H18N2O3, CAS 338400-32-1
(2E)-2-[2-(3,5-Dimethylphenyl)hydrazin-1-ylidene]-3-(4-methoxyphenyl)-3-oxopropanal
CAS 338400-32-1C18H18N2O3
3-(4-Chlorophenyl)-2-[2-(4-methylphenyl)hydrazono]-3-oxopropanal chemical structure, C16H13ClN2O2, CAS 338400-45-6
3-(4-Chlorophenyl)-2-[2-(4-methylphenyl)hydrazono]-3-oxopropanal
CAS 338400-45-6C16H13ClN2O2
(Z)-2-[(2-Chlorophenyl)diazenyl]-3-hydroxy-1-phenylprop-2-en-1-one chemical structure, C15H11ClN2O2
(Z)-2-[(2-Chlorophenyl)diazenyl]-3-hydroxy-1-phenylprop-2-en-1-one
C15H11ClN2O2
2-[2-(4-Fluorophenyl)hydrazono]-3-(4-methoxyphenyl)-3-oxopropanal chemical structure, C16H13FN2O3, CAS 338414-29-2
2-[2-(4-Fluorophenyl)hydrazono]-3-(4-methoxyphenyl)-3-oxopropanal
CAS 338414-29-2C16H13FN2O3
3-(4-Methoxyphenyl)-2-[2-(4-methoxyphenyl)hydrazono]-3-oxopropanal chemical structure, C17H16N2O4
3-(4-Methoxyphenyl)-2-[2-(4-methoxyphenyl)hydrazono]-3-oxopropanal
C17H16N2O4
(2E)-3-Oxo-3-phenyl-2-(2-phenylhydrazin-1-ylidene)propanal chemical structure, C15H12N2O2
(2E)-3-Oxo-3-phenyl-2-(2-phenylhydrazin-1-ylidene)propanal
C15H12N2O2
2-[(3,5-Dimethylphenyl)diazenyl]-3-hydroxy-1-(4-methoxyphenyl)prop-2-en-1-one chemical structure, C18H18N2O3
2-[(3,5-Dimethylphenyl)diazenyl]-3-hydroxy-1-(4-methoxyphenyl)prop-2-en-1-one
C18H18N2O3
3-Hydroxy-1-phenyl-2-[[3-(trifluoromethyl)phenyl]diazenyl]prop-2-en-1-one chemical structure, C16H11F3N2O2, CAS 339279-39-9
3-Hydroxy-1-phenyl-2-[[3-(trifluoromethyl)phenyl]diazenyl]prop-2-en-1-one
CAS 339279-39-9C16H11F3N2O2
3-(4-Methoxyphenyl)-3-oxo-2-{2-[4-(trifluoromethoxy)phenyl]hydrazono}propanal chemical structure, C17H13F3N2O4
3-(4-Methoxyphenyl)-3-oxo-2-{2-[4-(trifluoromethoxy)phenyl]hydrazono}propanal
C17H13F3N2O4