Murcko scaffold
Ring system with 5 rings and 32 atoms
21 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 32
- Chemicals
- 21
- With full pages
- 4
Scaffold SMILES
O=C(Nc1ccccc1)C1(C(=O)Nc2ccc(Oc3ccnc4ccccc34)cc2)CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 21 of 21 chemicals
Cabozantinib S-malate
CAS 1140909-48-3C32H30FN3O10
Cabozantinib
CAS 849217-68-1C28H24FN3O5
Cabozantinib impurity C
CAS 849221-94-9C28H25N3O5
Cabozantinib-d4
CAS 1802168-53-1C28H24FN3O5
Cabozantinib N-oxide
CAS 1621681-63-7C28H24FN3O6
Cabozantinib metabolite M9
CAS 1628530-40-4C28H24FN3O9S
Cabozantinib oxidation B
CAS 1628530-38-0C28H24FN3O6
Cabozantinib metabolite M12
CAS 1628530-45-9C28H24FN3O9S
Dimethyl cabozantinib
CAS 1628530-47-1C27H22FN3O5
N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-3-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
CAS 1628530-41-5C28H24FN3O6
N'1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide hydrochloride
CAS 1817759-42-4C28H25ClFN3O5
3-(3-(3-((4-(2-Fluoro-4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6-methoxyquinolin-7-yl)oxy)propoxy)propoxy)propanoic acid
CAS 2230826-10-3C36H37F2N3O9
tert-Butyl 3-(3-(3-((4-(2-fluoro-4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6-methoxyquinolin-7-yl)oxy)propoxy)propoxy)propanoate
CAS 2230826-09-0C40H45F2N3O9
![N-[3-Fluoro-4-[(7-hydroxy-6-methoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide chemical structure, C27H21F2N3O5, CAS 849217-50-1](/s/DBCXPLBWGBAQKL-UHFFFAOYSA-N.svg)
N-[3-Fluoro-4-[(7-hydroxy-6-methoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
CAS 849217-50-1C27H21F2N3O5
Desmethylcabozantinib
CAS 1628530-42-6C27H22FN3O5
Zanzalintinib
CAS 2367004-54-2C29H25FN4O5
Canlitinib
CAS 2222730-78-9C33H31F2N3O7
Cabozantinib-d6
CAS 1802168-46-2C28H24FN3O5
Zanzalintinib fumarate
CAS 2444285-59-8C62H54F2N8O14
Cabozantinib sulfate
CAS 3057960-44-5C28H26FN3O9S
Cabozantinib laurylsulfate
CAS 3052225-77-8C40H50FN3O9S