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Murcko scaffold

1-(1,3,4-Thiadiazol-2-yl)-1,4-diazepane scaffold

16 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
16
With full pages
3
Scaffold SMILES

c1nnc(N2CCCNCC2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(1,3,4-Thiadiazol-2-yl)-1,4-diazepane page
Murcko scaffold c1nnc(N2CCCNCC2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

1-(1,3,4-Thiadiazol-2-yl)-1,4-diazepane chemical structure, C7H12N4S, CAS 303160-12-5
1-(1,3,4-Thiadiazol-2-yl)-1,4-diazepane
CAS 303160-12-5C7H12N4S
tert-Butyl 4-(5-bromo-1,3,4-thiadiazol-2-yl)-1,4-diazepane-1-carboxylate chemical structure, C12H19BrN4O2S, CAS 1357147-44-4
tert-Butyl 4-(5-bromo-1,3,4-thiadiazol-2-yl)-1,4-diazepane-1-carboxylate
CAS 1357147-44-4C12H19BrN4O2S
1-(5-Bromo-1,3,4-thiadiazol-2-yl)-1,4-diazepane chemical structure, C7H11BrN4S, CAS 1357147-39-7
1-(5-Bromo-1,3,4-thiadiazol-2-yl)-1,4-diazepane
CAS 1357147-39-7C7H11BrN4S
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepane hydrochloride chemical structure, C8H12ClF3N4S, CAS 1803607-39-7
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepane hydrochloride
CAS 1803607-39-7C8H12ClF3N4S
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepane chemical structure, C8H11F3N4S, CAS 946409-45-6
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepane
CAS 946409-45-6C8H11F3N4S
1-{4-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl}but-2-yn-1-one chemical structure, C12H13F3N4OS, CAS 1825511-70-3
1-{4-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl}but-2-yn-1-one
CAS 1825511-70-3C12H13F3N4OS
1-{4-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl}prop-2-en-1-one chemical structure, C11H13F3N4OS, CAS 2093801-39-7
1-{4-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl}prop-2-en-1-one
CAS 2093801-39-7C11H13F3N4OS
2-(4-Methyl-1,4-diazepan-1-yl)-1,3,4-thiadiazole chemical structure, C8H14N4S, CAS 2034283-61-7
2-(4-Methyl-1,4-diazepan-1-yl)-1,3,4-thiadiazole
CAS 2034283-61-7C8H14N4S
2-Chloro-1-[4-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl]propan-1-one chemical structure, C11H14ClF3N4OS, CAS 2411285-39-5
2-Chloro-1-[4-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl]propan-1-one
CAS 2411285-39-5C11H14ClF3N4OS
2-Chloro-1-[4-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl]ethanone chemical structure, C10H12ClF3N4OS, CAS 2411244-20-5
2-Chloro-1-[4-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl]ethanone
CAS 2411244-20-5C10H12ClF3N4OS
1-Methanesulfonyl-4-(5-methyl-1,3,4-thiadiazol-2-yl)-1,4-diazepane chemical structure, C9H16N4O2S2, CAS 2877628-55-0
1-Methanesulfonyl-4-(5-methyl-1,3,4-thiadiazol-2-yl)-1,4-diazepane
CAS 2877628-55-0C9H16N4O2S2
1-Methanesulfonyl-4-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1,4-diazepane chemical structure, C11H20N4O2S2, CAS 2877637-94-8
1-Methanesulfonyl-4-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1,4-diazepane
CAS 2877637-94-8C11H20N4O2S2
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-4-methanesulfonyl-1,4-diazepane chemical structure, C12H22N4O2S2, CAS 2877630-72-1
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-4-methanesulfonyl-1,4-diazepane
CAS 2877630-72-1C12H22N4O2S2
2-(1,4-Diazepan-1-yl)-5-isopropyl-1,3,4-thiadiazole chemical structure, C10H18N4S, CAS 2749367-16-4
2-(1,4-Diazepan-1-yl)-5-isopropyl-1,3,4-thiadiazole
CAS 2749367-16-4C10H18N4S
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,4-diazepane chemical structure, C11H20N4S, CAS 2749634-10-2
1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,4-diazepane
CAS 2749634-10-2C11H20N4S
1-(1,3,4-Thiadiazol-2-yl)-1,4-diazepane dihydrochloride chemical structure, C7H14Cl2N4S, CAS 2514593-11-2
1-(1,3,4-Thiadiazol-2-yl)-1,4-diazepane dihydrochloride
CAS 2514593-11-2C7H14Cl2N4S