Murcko scaffold
Ring system with 5 rings and 28 atoms
16 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 28
- Chemicals
- 16
- With full pages
- 6
Scaffold SMILES
O=C(C1COc2ccccc2O1)N1CCN(c2ncc3ccccc3n2)CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 16 of 16 chemicals
Doxazosin
CAS 74191-85-8C23H25N5O5
Doxazosin mesylate
CAS 77883-43-3C24H29N5O8S
6-Hydroxydoxazosin
CAS 102932-28-5C23H25N5O6
Doxazosin methanesulfonate, (R)-
CAS 156154-38-0C24H29N5O8S
Doxazosin, (R)-
CAS 70918-17-1C23H25N5O5
Doxazosin methanesulfonate, (S)-
CAS 156154-10-8C24H29N5O8S
Doxazosin, (S)-
CAS 104874-86-4C23H25N5O5
Doxazosin monohydrochloride
CAS 70918-01-3C23H26ClN5O5
Doxazosin hydrochloride, (S)-
CAS 70918-18-2C23H26ClN5O5
Doxazosin hydrochloride, (R)-
CAS 77173-63-8C23H26ClN5O5
- chemical structure, C24H27N5O5, CAS 70918-27-3](/s/PZLDMJQEKRSBKQ-UHFFFAOYSA-N.svg)
Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-2-methyl-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)-
CAS 70918-27-3C24H27N5O5
Doxazosin D8
CAS 1126848-44-9C23H25N5O5
(4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl)(2,3-dihydro-1,4-benzodioxin-2-yl)methanone
CAS 102932-26-3C22H23N5O5
Doxazosin-d8 hydrochloride
CAS 1219803-95-8C23H26ClN5O5
7-Hydroxydoxazosin
CAS 102932-25-2C22H23N5O5
-, acetate (1:2) chemical structure, C27H33N5O9, CAS 2148918-81-2](/s/WMKFDVVIOWSNEY-UHFFFAOYSA-N.svg)
Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)-, acetate (1:2)
CAS 2148918-81-2C27H33N5O9