CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 16 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
8
With full pages
5
Scaffold SMILES

O=C1CCCc2[nH]c(-c3ccccc3)nc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCc2[nH]c(-c3ccccc3)nc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1-Hydroxy-2-phenyl-1,5,6,7-tetrahydro-4H-benzimidazol-4-one chemical structure, C13H12N2O2, CAS 257869-87-7
1-Hydroxy-2-phenyl-1,5,6,7-tetrahydro-4H-benzimidazol-4-one
CAS 257869-87-7C13H12N2O2
2-(4-Fluorophenyl)-1-hydroxy-6,7-dihydro-5H-benzimidazol-4-one chemical structure, C13H11FN2O2, CAS 352024-49-8
2-(4-Fluorophenyl)-1-hydroxy-6,7-dihydro-5H-benzimidazol-4-one
CAS 352024-49-8C13H11FN2O2
2-(3-Chlorophenyl)-1-hydroxy-1,5,6,7-tetrahydro-4H-benzimidazol-4-one chemical structure, C13H11ClN2O2, CAS 317841-84-2
2-(3-Chlorophenyl)-1-hydroxy-1,5,6,7-tetrahydro-4H-benzimidazol-4-one
CAS 317841-84-2C13H11ClN2O2
1-Hydroxy-2-(4-methoxyphenyl)-1,5,6,7-tetrahydro-4H-benzimidazol-4-one chemical structure, C14H14N2O3, CAS 300590-03-8
1-Hydroxy-2-(4-methoxyphenyl)-1,5,6,7-tetrahydro-4H-benzimidazol-4-one
CAS 300590-03-8C14H14N2O3
2-(2-Chlorophenyl)-1-hydroxy-6,7-dihydro-5H-benzimidazol-4-one chemical structure, C13H11ClN2O2, CAS 352647-28-0
2-(2-Chlorophenyl)-1-hydroxy-6,7-dihydro-5H-benzimidazol-4-one
CAS 352647-28-0C13H11ClN2O2
1-Hydroxy-2-(3-nitrophenyl)-1,5,6,7-tetrahydro-4H-benzimidazol-4-one chemical structure, C13H11N3O4, CAS 310447-13-3
1-Hydroxy-2-(3-nitrophenyl)-1,5,6,7-tetrahydro-4H-benzimidazol-4-one
CAS 310447-13-3C13H11N3O4
1-Hydroxy-2-(4-nitrophenyl)-6,7-dihydro-5H-benzimidazol-4-one chemical structure, C13H11N3O4, CAS 302795-78-4
1-Hydroxy-2-(4-nitrophenyl)-6,7-dihydro-5H-benzimidazol-4-one
CAS 302795-78-4C13H11N3O4
3,5,6,7-Tetrahydro-6,6-dimethyl-2-phenyl-4H-benzimidazol-4-one chemical structure, C15H16N2O, CAS 77335-96-7
3,5,6,7-Tetrahydro-6,6-dimethyl-2-phenyl-4H-benzimidazol-4-one
CAS 77335-96-7C15H16N2O