Murcko scaffold
4-Piperidone scaffold
763 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 763
- With full pages
- 109
Scaffold SMILES
O=C1CCNCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 763 chemicals
2,2,6,6-Tetramethyl-4-piperidone
CAS 826-36-8C9H17NO
3-Piperidinecarboxylic acid, 1-methyl-4-oxo-, methyl ester
CAS 13221-89-1C8H13NO3
4-Piperidone
CAS 41661-47-6C5H9NO
Ethyl 4-oxo-1-piperidinecarboxylate
CAS 29976-53-2C8H13NO3
1-Nitroso-4-piperidone
CAS 55556-91-7C5H8N2O2
2,2,6,6-Tetramethyl-1-nitroso-4-piperidone
CAS 640-01-7C9H16N2O2
1-tert-Butyl-4-piperidone
CAS 1465-76-5C9H17NO
1-Methyl-4-piperidone
CAS 1445-73-4C6H11NO
1-Ethylpiperidin-4-one
CAS 3612-18-8C7H13NO
1-(Isopropyl)-4-piperidone
CAS 5355-68-0C8H15NO
1-Ethyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate
CAS 19821-27-3C10H15NO5
4-Piperidinone, 3,5-dibromo-2,2,6,6-tetramethyl-, hydrobromide (1:1)
CAS 19971-12-1C9H16Br3NO
3,5-Dibromo-2,2,6,6-tetramethylpiperidin-4-one
CAS 57167-75-6C9H15Br2NO
1-Butyl-4-piperidone
CAS 23081-86-9C9H17NO
1-Propyl-4-piperidone
CAS 23133-37-1C8H15NO
4-Piperidinone, 2,2,6,6-tetramethyl-, hydrochloride (1:1)
CAS 33973-59-0C9H18ClNO
1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine
CAS 3637-11-4C9H17NO2
1,3-Dimethyl-4-piperidone
CAS 4629-80-5C7H13NO
3-Piperidinecarboxylic acid, 4-oxo-, ethyl ester, hydrochloride (1:1)
CAS 4644-61-5C8H14ClNO3
4-Oxo-piperidine-3-carboxylic acid ethyl ester
CAS 67848-59-3C8H13NO3
4-Piperidone, 5-(diethylamino)-1,2,5-trimethyl-, dihydrochloride
CAS 597-00-2C12H26Cl2N2O
5-Ethoxy-1,1,2,5-tetramethyl-4-oxopiperidin-1-ium iodide
CAS 597-39-7C11H22INO2
Methyl 4-oxopiperidine-1-carboxylate
CAS 29976-54-3C7H11NO3
N-Acetyl-4-piperidone
CAS 3211-06-1C7H11NO2
- 1 suppliers1-Nitroso-3-methyl-4-piperidone71677-48-0C6H10N2O2
- 4-Piperidinone,1-chloro-2,2,6,6-tetramethyl-38951-83-6C9H16ClNO
- Oxalic acid--1,2,2,6,6-pentamethylpiperidin-4-one (1/1)6636-26-6C12H21NO5
- 1 suppliers1,2,2,6,6-Pentamethyl-4-piperidone5554-54-1C10H19NO
- Dimethyl 1,2,6-trimethyl-4-oxopiperidine-3,5-dicarboxylate46863-19-8C12H19NO5
- 3,5-Dibromo-1-hydroxy-2,2,6,6-tetramethylpiperidin-4-one66314-86-1C9H15Br2NO2
- Ethyl 1-methyl-4-oxopiperidine-3-carboxylate25012-72-0C9H15NO3
- 1,1-Dimethyl-4-oxopiperidinium iodide131703-79-2C7H14NO+
- 1-Methyl-3,5-dinitropiperidin-4-one70688-17-4C6H9N3O5
- 3-Acetyl-1-methylpiperidin-4-one126832-84-6C8H13NO2
- 1,2,5-Trimethyl-4-piperidinone7516-33-8C8H15NO
- 2-Propenenitrile, 3-(2,2,6,6-tetramethyl-4-oxo-1-piperidinyl)-, (Z)-89422-24-2C12H18N2O
- Rel-(2R,5S)-1,2,5-trimethylpiperidin-4-oneC8H15NO
- tert-Butyl 4-oxopiperidine-1-carboxylate79099-07-3C10H17NO3
- (3R)-1,3-Dimethylpiperidin-4-one1527494-98-9C7H13NO
- 4-Piperidinone, 1,2,3-trimethyl-, trans-18485-98-8C8H15NO
- (3R,5R)-1,3,5-Trimethylpiperidin-4-one31499-19-1C8H15NO
- 4-Oxopiperidine-1-carboxamide306976-42-1C6H10N2O2
- 1-(3-Methylbut-2-en-1-yl)piperidin-4-one924867-35-6C10H17NO
- (3S)-1,3-Dimethylpiperidin-4-one1527494-96-7C7H13NO
- Piperonylamine320589-77-3C5H12ClNO2
- 3-Amino-2,2,6,6-tetramethylpiperidin-4-one76505-59-4C9H18N2O
- 4-Piperidinone, 1-(2-ethoxyethyl)-3-methyl-, hydrochloride (1:1)109629-31-4C10H20ClNO2
- 1-Piperidinepropanoic acid, 2,5-dimethyl-4-oxo-, methyl ester, trans-110998-16-8C11H19NO3
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
