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Murcko scaffold

Ring system with 10 rings and 34 atoms

6 chemicals on CompoundList share this ring system.

Rings
10
Scaffold atoms
34
Chemicals
6
With full pages
4
Scaffold SMILES

C=C1Cc2ccc3[nH]c4c5c3c2C2C(COC5C3CCC5C(CCC6OCCC7OC675)C43)CC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1Cc2ccc3[nH]c4c5c3c2C2C(COC5C3CCC5C(CCC6OCCC7OC675)C43)CC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Penitrem B chemical structure, C37H45NO5, CAS 11076-67-8
Penitrem B
CAS 11076-67-8C37H45NO5
Penitrem F chemical structure, C37H44ClNO5, CAS 78213-65-7
Penitrem F
CAS 78213-65-7C37H44ClNO5
Penitrem E chemical structure, C37H45NO6, CAS 78213-66-8
Penitrem E
CAS 78213-66-8C37H45NO6
Penitrem A chemical structure, C37H44ClNO6, CAS 12627-35-9
Penitrem A
CAS 12627-35-9C37H44ClNO6
Penitrem chemical structure, C37H44ClNO5, CAS 37203-49-9
Penitrem
CAS 37203-49-9C37H44ClNO5
7,8-(Epoxymethano)-2H,6H-cyclobuta[5,6]benz[1,2-e]oxireno[4a(2),4a(2)a]-1-benzopyrano[5a(2),6a(2):6,7]indeno[1,2-b]indole-3,4b,7d(5H,7H)-triol, 12-chloro-3,3a,6a,8,9,9a,10,11,14,14b,14c,15,16,16a-tetradecahydro-14b,14c,17,17-tetramethyl-10-methylene-2-(1-methylethenyl)-, (2R,3S,3aR,4aS,4bS,6aR,7S,7dR,8R,9aR,14bS,14cR,16aS)- chemical structure, C37H44ClNO6, CAS 12679-82-2
7,8-(Epoxymethano)-2H,6H-cyclobuta[5,6]benz[1,2-e]oxireno[4a(2),4a(2)a]-1-benzopyrano[5a(2),6a(2):6,7]indeno[1,2-b]indole-3,4b,7d(5H,7H)-triol, 12-chloro-3,3a,6a,8,9,9a,10,11,14,14b,14c,15,16,16a-tetradecahydro-14b,14c,17,17-tetramethyl-10-methylene-2-(1-methylethenyl)-, (2R,3S,3aR,4aS,4bS,6aR,7S,7dR,8R,9aR,14bS,14cR,16aS)-
CAS 12679-82-2C37H44ClNO6