Murcko scaffold
Isothiazolo(5,4-b)pyridine scaffold
96 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 96
- With full pages
- 7
Scaffold SMILES
c1cnc2sncc2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 96 chemicals
![2-[3-(Hydroxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]acetic acid chemical structure, C11H12N2O3S, CAS 2060021-48-7](/s/KONSAONCLDASBP-UHFFFAOYSA-N.svg)
2-[3-(Hydroxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]acetic acid
CAS 2060021-48-7C11H12N2O3S
![5-[(tert-Butoxy)carbonyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid chemical structure, C14H16N2O4S, CAS 2060005-23-2](/s/KXFAQGVVBWAQEP-UHFFFAOYSA-N.svg)
5-[(tert-Butoxy)carbonyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid
CAS 2060005-23-2C14H16N2O4S
![3-Bromo-5-ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine chemical structure, C10H11BrN2S, CAS 2060038-79-9](/s/LMZLIMCCIDLJIO-UHFFFAOYSA-N.svg)
3-Bromo-5-ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine
CAS 2060038-79-9C10H11BrN2S
![Methyl 3-(hydroxymethyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate chemical structure, C13H16N2O3S, CAS 2060033-04-5](/s/LWIZSTFRULQSAB-UHFFFAOYSA-N.svg)
Methyl 3-(hydroxymethyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate
CAS 2060033-04-5C13H16N2O3S
![5-Ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid chemical structure, C11H12N2O2S, CAS 2060058-76-4](/s/MKUUFUPKYQSVQW-UHFFFAOYSA-N.svg)
5-Ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid
CAS 2060058-76-4C11H12N2O2S
![5-(Ethoxycarbonyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid chemical structure, C12H12N2O4S, CAS 2060026-57-3](/s/NJHPOKBGVZNUHS-UHFFFAOYSA-N.svg)
5-(Ethoxycarbonyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid
CAS 2060026-57-3C12H12N2O4S
![6-Ethyl-4,5-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carbaldehyde chemical structure, C11H12N2OS, CAS 2059975-19-6](/s/OAOUUXLLKUXFOU-UHFFFAOYSA-N.svg)
6-Ethyl-4,5-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carbaldehyde
CAS 2059975-19-6C11H12N2OS
![Ethyl 3-formyl-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate chemical structure, C14H16N2O3S, CAS 2060062-08-8](/s/OEOOUJOZDPSJAB-UHFFFAOYSA-N.svg)
Ethyl 3-formyl-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate
CAS 2060062-08-8C14H16N2O3S
![[3-(Aminomethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]methanol chemical structure, C10H13N3OS, CAS 2060044-33-7](/s/OIHDKZMJRDWUGR-UHFFFAOYSA-N.svg)
[3-(Aminomethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]methanol
CAS 2060044-33-7C10H13N3OS
![5-Ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carbaldehyde chemical structure, C11H12N2OS, CAS 2060058-28-6](/s/PJWPSVMNECAOHE-UHFFFAOYSA-N.svg)
5-Ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carbaldehyde
CAS 2060058-28-6C11H12N2OS
![Ethyl 2-[3-(aminomethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]acetate chemical structure, C13H17N3O2S, CAS 2060026-49-3](/s/PPBUGEMUKXVLSY-UHFFFAOYSA-N.svg)
Ethyl 2-[3-(aminomethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]acetate
CAS 2060026-49-3C13H17N3O2S
![Ethyl 3-(aminomethyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate chemical structure, C14H19N3O2S, CAS 2060051-94-5](/s/QBYBPYQDWDIZSM-UHFFFAOYSA-N.svg)
Ethyl 3-(aminomethyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate
CAS 2060051-94-5C14H19N3O2S
![5-(Carboxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid chemical structure, C11H10N2O4S, CAS 2060021-57-8](/s/QPAGTMUPFSFJDV-UHFFFAOYSA-N.svg)
5-(Carboxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid
CAS 2060021-57-8C11H10N2O4S
![5-(Hydroxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid chemical structure, C10H10N2O3S, CAS 2060062-16-8](/s/REMWLMFHUBJPLL-UHFFFAOYSA-N.svg)
5-(Hydroxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid
CAS 2060062-16-8C10H10N2O3S
![Ethyl 2-{3-formyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl}acetate chemical structure, C13H14N2O3S, CAS 2060033-10-3](/s/RHYTVXCJWDLFPB-UHFFFAOYSA-N.svg)
Ethyl 2-{3-formyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl}acetate
CAS 2060033-10-3C13H14N2O3S
![Ethyl 3-(aminomethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate chemical structure, C12H15N3O2S, CAS 2060044-57-5](/s/RTCHFJDGCIAEHN-UHFFFAOYSA-N.svg)
Ethyl 3-(aminomethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate
CAS 2060044-57-5C12H15N3O2S
![Methyl 3-(aminomethyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate chemical structure, C13H17N3O2S, CAS 2060062-04-4](/s/SBGXLKMLHBVSTN-UHFFFAOYSA-N.svg)
Methyl 3-(aminomethyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate
CAS 2060062-04-4C13H17N3O2S
![2-{3-Bromo-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl}acetic acid chemical structure, C10H9BrN2O2S, CAS 2059950-14-8](/s/SJVPNZYDGXQBQH-UHFFFAOYSA-N.svg)
2-{3-Bromo-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl}acetic acid
CAS 2059950-14-8C10H9BrN2O2S
![Methyl 3-bromo-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate chemical structure, C12H13BrN2O2S, CAS 2060026-44-8](/s/SSTANXCSIFMKIE-UHFFFAOYSA-N.svg)
Methyl 3-bromo-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate
CAS 2060026-44-8C12H13BrN2O2S
![4,6-Dimethyl-5-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-3-carbaldehyde chemical structure, C12H14N2OS, CAS 2060044-85-9](/s/SWLGNZGKQDPBCJ-UHFFFAOYSA-N.svg)
4,6-Dimethyl-5-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-3-carbaldehyde
CAS 2060044-85-9C12H14N2OS
![3-Bromo-6-ethyl-4,5-dimethyl-[1,2]thiazolo[5,4-b]pyridine chemical structure, C10H11BrN2S, CAS 2060032-88-2](/s/SWWOOVGLAWCFPR-UHFFFAOYSA-N.svg)
3-Bromo-6-ethyl-4,5-dimethyl-[1,2]thiazolo[5,4-b]pyridine
CAS 2060032-88-2C10H11BrN2S
![{3-Bromo-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl}methanol chemical structure, C9H9BrN2OS, CAS 2059974-87-5](/s/SZVDGXVBNGXKGZ-UHFFFAOYSA-N.svg)
{3-Bromo-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl}methanol
CAS 2059974-87-5C9H9BrN2OS
![3-Bromo-4,6-dimethyl-5-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine chemical structure, C11H13BrN2S, CAS 2060058-07-1](/s/UOEDSHVWUTVDKB-UHFFFAOYSA-N.svg)
3-Bromo-4,6-dimethyl-5-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine
CAS 2060058-07-1C11H13BrN2S
![5-(2-Ethoxy-2-oxoethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid chemical structure, C13H14N2O4S, CAS 2060033-17-0](/s/VDQMHPQITZONOP-UHFFFAOYSA-N.svg)
5-(2-Ethoxy-2-oxoethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid
CAS 2060033-17-0C13H14N2O4S
- 6-Ethyl-4,5-dimethyl-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid2060044-93-9C11H12N2O2S
- {5-Ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl}methanamine2060038-83-5C11H15N3S
- {5-Ethyl-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl}methanol2060058-26-4C11H14N2OS
- 2-[3-(Aminomethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]acetic acid2060032-96-2C11H13N3O2S
- 5-(Ethoxycarbonyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-3-carboxylic acid2059975-23-2C14H16N2O4S
- Ethyl 2-{3-bromo-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl}acetate2059974-99-9C12H13BrN2O2S
- Ethyl 3-(hydroxymethyl)-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate2060062-07-7C14H18N2O3S
- [4,6-Dimethyl-5-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridin-3-yl]methanol2060005-13-0C12H16N2OS
- {6-Ethyl-4,5-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl}methanol2060044-82-6C11H14N2OS
- Methyl 3-formyl-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate2059950-37-5C13H14N2O3S
- Ethyl 3-bromo-4-methyl-6-(propan-2-yl)-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate2060044-26-8C13H15BrN2O2S
- 2-[3-(Hydroxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]ethan-1-ol2060038-87-9C11H14N2O2S
- Ethyl 2-[3-(hydroxymethyl)-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-5-yl]acetate2060044-41-7C13H16N2O3S
- Isothiazolo[5,4-b]pyridin-6-amine1352905-20-4C6H5N3S
- Ethyl 4-chloro-[1,2]thiazolo[5,4-b]pyridine-5-carboxylate2156492-06-5C9H7ClN2O2S
- 5-(Trifluoromethyl)-[1,2]thiazolo[5,4-b]pyridine2413875-22-4C7H3F3N2S
- (5-Bromoisothiazolo[5,4-b]pyridin-3-yl)methanol2450990-00-6C7H5BrN2OS
- 5-Bromo-3-(bromomethyl)isothiazolo[5,4-b]pyridine2450989-99-6C7H4Br2N2S
- 3-Methyl-5-(trifluoromethyl)-[1,2]thiazolo[5,4-b]pyridine2413878-90-5C8H5F3N2S
- N-{4,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl}prop-2-enamide2308316-52-9C11H11N3OS
- 5-Methanesulfonyl-3-methyl-[1,2]thiazolo[5,4-b]pyridine2825007-57-4C8H8N2O2S2
- 6-(Trifluoromethyl)-[1,2]thiazolo[5,4-b]pyridine-4-carboxylic acid2137649-02-4C8H3F3N2O2S
- 3,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridine-5-carboxylic acid2913426-68-1C9H8N2O2S
- Isothiazolo[5,4-b]pyridin-5-amine2768029-29-2C6H5N3S
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