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Murcko scaffold

Ring system with 3 rings and 25 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
24
With full pages
5
Scaffold SMILES

O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCCCCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCCCCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-[5-(Azepane-1-sulfonyl)-2-chloro-benzoylamino]-benzoic acid chemical structure, C20H21ClN2O5S, CAS 312502-59-3
2-[5-(Azepane-1-sulfonyl)-2-chloro-benzoylamino]-benzoic acid
CAS 312502-59-3C20H21ClN2O5S
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(2-hydroxyphenyl)benzamide chemical structure, C19H21ClN2O4S, CAS 352671-70-6
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(2-hydroxyphenyl)benzamide
CAS 352671-70-6C19H21ClN2O4S
3-(Azepan-1-ylsulfonyl)-4-methyl-N-phenylbenzamide chemical structure, C20H24N2O3S, CAS 445225-69-4
3-(Azepan-1-ylsulfonyl)-4-methyl-N-phenylbenzamide
CAS 445225-69-4C20H24N2O3S
3-(Azepan-1-ylsulfonyl)-N-(4-((difluoromethyl)sulfonyl)phenyl)benzamide chemical structure, C20H22F2N2O5S2, CAS 690249-37-7
3-(Azepan-1-ylsulfonyl)-N-(4-((difluoromethyl)sulfonyl)phenyl)benzamide
CAS 690249-37-7C20H22F2N2O5S2
5-(Azepan-1-ylsulfonyl)-2-chloro-N-(3-hydroxyphenyl)benzamide chemical structure, C19H21ClN2O4S, CAS 312504-70-4
5-(Azepan-1-ylsulfonyl)-2-chloro-N-(3-hydroxyphenyl)benzamide
CAS 312504-70-4C19H21ClN2O4S
3-(Azepan-1-ylsulfonyl)-N-(3-bromophenyl)benzamide chemical structure, C19H21BrN2O3S, CAS 420831-40-9
3-(Azepan-1-ylsulfonyl)-N-(3-bromophenyl)benzamide
CAS 420831-40-9C19H21BrN2O3S
3-(Azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide chemical structure, C19H21N3O5S, CAS 330461-64-8
3-(Azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide
CAS 330461-64-8C19H21N3O5S
N-(4-Acetamidophenyl)-3-(azepan-1-ylsulfonyl)benzamide chemical structure, C21H25N3O4S, CAS 763099-91-8
N-(4-Acetamidophenyl)-3-(azepan-1-ylsulfonyl)benzamide
CAS 763099-91-8C21H25N3O4S
3-(Azepan-1-ylsulfonyl)-N-[3,5-bis(trifluoromethyl)phenyl]benzamide chemical structure, C21H20F6N2O3S, CAS 690249-36-6
3-(Azepan-1-ylsulfonyl)-N-[3,5-bis(trifluoromethyl)phenyl]benzamide
CAS 690249-36-6C21H20F6N2O3S
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(4-fluorophenyl)benzamide chemical structure, C19H20ClFN2O3S, CAS 352671-69-3
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(4-fluorophenyl)benzamide
CAS 352671-69-3C19H20ClFN2O3S
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(2,4-dimethoxyphenyl)benzamide chemical structure, C21H25ClN2O5S, CAS 863321-27-1
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(2,4-dimethoxyphenyl)benzamide
CAS 863321-27-1C21H25ClN2O5S
5-(Azepan-1-ylsulfonyl)-N-(3-chloro-4-fluorophenyl)-2-fluorobenzamide chemical structure, C19H19ClF2N2O3S, CAS 451512-06-4
5-(Azepan-1-ylsulfonyl)-N-(3-chloro-4-fluorophenyl)-2-fluorobenzamide
CAS 451512-06-4C19H19ClF2N2O3S
5-(Azepan-1-ylsulfonyl)-N-(3,5-dichlorophenyl)-2-fluorobenzamide chemical structure, C19H19Cl2FN2O3S, CAS 451481-09-7
5-(Azepan-1-ylsulfonyl)-N-(3,5-dichlorophenyl)-2-fluorobenzamide
CAS 451481-09-7C19H19Cl2FN2O3S
5-(Azepan-1-ylsulfonyl)-N-(3-chlorophenyl)-2-fluorobenzamide chemical structure, C19H20ClFN2O3S, CAS 451474-68-3
5-(Azepan-1-ylsulfonyl)-N-(3-chlorophenyl)-2-fluorobenzamide
CAS 451474-68-3C19H20ClFN2O3S
3-(Azepan-1-ylsulfonyl)-4-methyl-N-(4-(methylsulfonyl)phenyl)benzamide chemical structure, C21H26N2O5S2, CAS 900135-91-3
3-(Azepan-1-ylsulfonyl)-4-methyl-N-(4-(methylsulfonyl)phenyl)benzamide
CAS 900135-91-3C21H26N2O5S2
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(4-(methylsulfonyl)phenyl)benzamide chemical structure, C20H23ClN2O5S2, CAS 900135-72-0
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(4-(methylsulfonyl)phenyl)benzamide
CAS 900135-72-0C20H23ClN2O5S2
3-(Azepan-1-ylsulfonyl)-N-(4-(methylsulfonyl)phenyl)benzamide chemical structure, C20H24N2O5S2, CAS 900135-67-3
3-(Azepan-1-ylsulfonyl)-N-(4-(methylsulfonyl)phenyl)benzamide
CAS 900135-67-3C20H24N2O5S2
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(3-((difluoromethyl)sulfonyl)phenyl)benzamide chemical structure, C20H21ClF2N2O5S2, CAS 887863-43-6
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(3-((difluoromethyl)sulfonyl)phenyl)benzamide
CAS 887863-43-6C20H21ClF2N2O5S2
3-(Azepan-1-ylsulfonyl)-N-[2-(difluoromethoxy)phenyl]-4-methylbenzamide chemical structure, C21H24F2N2O4S, CAS 887198-88-1
3-(Azepan-1-ylsulfonyl)-N-[2-(difluoromethoxy)phenyl]-4-methylbenzamide
CAS 887198-88-1C21H24F2N2O4S
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(2-(difluoromethoxy)phenyl)benzamide chemical structure, C20H21ClF2N2O4S, CAS 887199-05-5
3-(Azepan-1-ylsulfonyl)-4-chloro-N-(2-(difluoromethoxy)phenyl)benzamide
CAS 887199-05-5C20H21ClF2N2O4S
3-(Azepan-1-ylsulfonyl)-N-(2,4-dimethoxyphenyl)-4-methylbenzamide chemical structure, C22H28N2O5S, CAS 863026-38-4
3-(Azepan-1-ylsulfonyl)-N-(2,4-dimethoxyphenyl)-4-methylbenzamide
CAS 863026-38-4C22H28N2O5S
5-(Azepan-1-ylsulfonyl)-N-(3,5-difluorophenyl)-2-hydroxybenzamide chemical structure, C19H20F2N2O4S, CAS 940983-93-7
5-(Azepan-1-ylsulfonyl)-N-(3,5-difluorophenyl)-2-hydroxybenzamide
CAS 940983-93-7C19H20F2N2O4S
Ethyl 4-(5-(azepan-1-ylsulfonyl)-2-hydroxybenzamido)benzoate chemical structure, C22H26N2O6S, CAS 941252-13-7
Ethyl 4-(5-(azepan-1-ylsulfonyl)-2-hydroxybenzamido)benzoate
CAS 941252-13-7C22H26N2O6S
5-(Azepan-1-ylsulfonyl)-N-(3-chlorophenyl)-2-hydroxybenzamide chemical structure, C19H21ClN2O4S, CAS 941252-17-1
5-(Azepan-1-ylsulfonyl)-N-(3-chlorophenyl)-2-hydroxybenzamide
CAS 941252-17-1C19H21ClN2O4S