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Murcko scaffold

4-(Piperidin-1-ylsulfonyl)-N-(thiazol-2-yl)benzamide scaffold

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
17
With full pages
3
Scaffold SMILES

O=C(Nc1nccs1)c1ccc(S(=O)(=O)N2CCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Piperidin-1-ylsulfonyl)-N-(thiazol-2-yl)benzamide page
Murcko scaffold O=C(Nc1nccs1)c1ccc(S(=O)(=O)N2CCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

4-(Piperidin-1-ylsulfonyl)-N-(thiazol-2-yl)benzamide chemical structure, C15H17N3O3S2, CAS 300572-51-4
4-(Piperidin-1-ylsulfonyl)-N-(thiazol-2-yl)benzamide
CAS 300572-51-4C15H17N3O3S2
4-((4-Methylpiperidin-1-yl)sulfonyl)-N-(thiazol-2-yl)benzamide chemical structure, C16H19N3O3S2, CAS 577753-24-3
4-((4-Methylpiperidin-1-yl)sulfonyl)-N-(thiazol-2-yl)benzamide
CAS 577753-24-3C16H19N3O3S2
Ethyl 2-(4-(piperidin-1-ylsulfonyl)benzamido)thiazole-5-carboxylate chemical structure, C18H21N3O5S2, CAS 868212-97-9
Ethyl 2-(4-(piperidin-1-ylsulfonyl)benzamido)thiazole-5-carboxylate
CAS 868212-97-9C18H21N3O5S2
Ethyl 2-(2-(4-(piperidin-1-ylsulfonyl)benzamido)thiazol-4-yl)acetate chemical structure, C19H23N3O5S2, CAS 361159-81-1
Ethyl 2-(2-(4-(piperidin-1-ylsulfonyl)benzamido)thiazol-4-yl)acetate
CAS 361159-81-1C19H23N3O5S2
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)thiazole-4-carboxylate chemical structure, C20H25N3O5S2, CAS 393837-45-1
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)thiazole-4-carboxylate
CAS 393837-45-1C20H25N3O5S2
Ethyl (2Z)-2-({4-[(3,5-dimethylpiperidin-1-yl)sulfonyl]benzoyl}imino)-3,4-dimethyl-2,3-dihydro-1,3-thiazole-5-carboxylate chemical structure, C22H29N3O5S2, CAS 393838-99-8
Ethyl (2Z)-2-({4-[(3,5-dimethylpiperidin-1-yl)sulfonyl]benzoyl}imino)-3,4-dimethyl-2,3-dihydro-1,3-thiazole-5-carboxylate
CAS 393838-99-8C22H29N3O5S2
Ethyl 3,4-dimethyl-2-(4-piperidin-1-ylsulfonylbenzoyl)imino-1,3-thiazole-5-carboxylate chemical structure, C20H25N3O5S2, CAS 394228-08-1
Ethyl 3,4-dimethyl-2-(4-piperidin-1-ylsulfonylbenzoyl)imino-1,3-thiazole-5-carboxylate
CAS 394228-08-1C20H25N3O5S2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-4-piperidin-1-ylsulfonylbenzamide chemical structure, C19H25N3O3S2, CAS 325979-87-1
N-(4-tert-Butyl-1,3-thiazol-2-yl)-4-piperidin-1-ylsulfonylbenzamide
CAS 325979-87-1C19H25N3O3S2
N-(4-(tert-Butyl)thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C20H27N3O3S2, CAS 683264-22-4
N-(4-(tert-Butyl)thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 683264-22-4C20H27N3O3S2
N-(5-Acetyl-4-methylthiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C20H25N3O4S2, CAS 361167-62-6
N-(5-Acetyl-4-methylthiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide
CAS 361167-62-6C20H25N3O4S2
(Z)-Ethyl 3,4-dimethyl-2-((4-((4-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)-2,3-dihydrothiazole-5-carboxylate chemical structure, C21H27N3O5S2, CAS 683767-22-8
(Z)-Ethyl 3,4-dimethyl-2-((4-((4-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)-2,3-dihydrothiazole-5-carboxylate
CAS 683767-22-8C21H27N3O5S2
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-4-methylthiazole-5-carboxylate chemical structure, C21H27N3O5S2, CAS 361167-61-5
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-4-methylthiazole-5-carboxylate
CAS 361167-61-5C21H27N3O5S2
Ethyl 2-(2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)thiazol-4-yl)acetate chemical structure, C21H27N3O5S2, CAS 361167-60-4
Ethyl 2-(2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)thiazol-4-yl)acetate
CAS 361167-60-4C21H27N3O5S2
Ethyl 3,4-dimethyl-2-[4-(3-methylpiperidin-1-yl)sulfonylbenzoyl]imino-1,3-thiazole-5-carboxylate chemical structure, C21H27N3O5S2, CAS 683767-23-9
Ethyl 3,4-dimethyl-2-[4-(3-methylpiperidin-1-yl)sulfonylbenzoyl]imino-1,3-thiazole-5-carboxylate
CAS 683767-23-9C21H27N3O5S2
4-((2-Ethylpiperidin-1-yl)sulfonyl)-N-(thiazol-2-yl)benzamide chemical structure, C17H21N3O3S2, CAS 864939-61-7
4-((2-Ethylpiperidin-1-yl)sulfonyl)-N-(thiazol-2-yl)benzamide
CAS 864939-61-7C17H21N3O3S2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-4-[(3-methylpiperidin-1-yl)sulfonyl]benzamide chemical structure, C20H27N3O3S2, CAS 683264-23-5
N-(4-tert-Butyl-1,3-thiazol-2-yl)-4-[(3-methylpiperidin-1-yl)sulfonyl]benzamide
CAS 683264-23-5C20H27N3O3S2
N-(4,5-Dimethylthiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide chemical structure, C17H21N3O3S2, CAS 923443-84-9
N-(4,5-Dimethylthiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide
CAS 923443-84-9C17H21N3O3S2