Murcko scaffold
Ring system with 5 rings and 28 atoms
27 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 28
- Chemicals
- 27
- With full pages
- 3
Scaffold SMILES
O=c1cc(-c2ccccc2)c2ccc3c(c2o1)CN(Cc1ccccc1)CO3
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 27 of 27 chemicals
![9-(4-Methoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H21NO4, CAS 858770-53-3](/s/VIJQPAOOVCBGSG-UHFFFAOYSA-N.svg)
9-(4-Methoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 858770-53-3C25H21NO4
![9-(4-Methylbenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H21NO3, CAS 859137-24-9](/s/UFHOGFIJBBFBJZ-UHFFFAOYSA-N.svg)
9-(4-Methylbenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 859137-24-9C25H21NO3
![4-Phenyl-9-(3,4,5-trimethoxybenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C27H25NO6, CAS 859139-32-5](/s/DVAQUYKXFMAKHH-UHFFFAOYSA-N.svg)
4-Phenyl-9-(3,4,5-trimethoxybenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 859139-32-5C27H25NO6
![6-Ethyl-9-(4-methoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C27H25NO4, CAS 859139-54-1](/s/FMRUCFIUYZBGKT-UHFFFAOYSA-N.svg)
6-Ethyl-9-(4-methoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 859139-54-1C27H25NO4
![9-(4-Chlorobenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C24H18ClNO3, CAS 853892-94-1](/s/WFLJNWYMLIZPHA-UHFFFAOYSA-N.svg)
9-(4-Chlorobenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853892-94-1C24H18ClNO3
![9-(4-Chlorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H20ClNO4, CAS 853892-95-2](/s/JENFLKJYLQOZMK-UHFFFAOYSA-N.svg)
9-(4-Chlorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853892-95-2C25H20ClNO4
![9-(3,4-Dimethoxybenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C27H25NO6, CAS 853893-26-2](/s/QBLVCTGAEWXTIE-UHFFFAOYSA-N.svg)
9-(3,4-Dimethoxybenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853893-26-2C27H25NO6
![4-(4-Methoxyphenyl)-9-(3,4,5-trimethoxybenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C28H27NO7, CAS 859859-49-7](/s/SEYUZPBBAGHEEB-UHFFFAOYSA-N.svg)
4-(4-Methoxyphenyl)-9-(3,4,5-trimethoxybenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 859859-49-7C28H27NO7
![6-Ethyl-4-phenyl-9-(3,4,5-trimethoxybenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C29H29NO6, CAS 859861-30-6](/s/AKFQFFJYBBEBQF-UHFFFAOYSA-N.svg)
6-Ethyl-4-phenyl-9-(3,4,5-trimethoxybenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 859861-30-6C29H29NO6
![9-(4-Methoxybenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C26H23NO5, CAS 853893-30-8](/s/SHXVKUMVDBMDRC-UHFFFAOYSA-N.svg)
9-(4-Methoxybenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853893-30-8C26H23NO5
![9-Benzyl-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H21NO4, CAS 853892-84-9](/s/GNAHIWSQNBTPIE-UHFFFAOYSA-N.svg)
9-Benzyl-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853892-84-9C25H21NO4
![9-(3,4-Dimethoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C26H23NO5, CAS 853893-25-1](/s/PKVKPQYTTIINDJ-UHFFFAOYSA-N.svg)
9-(3,4-Dimethoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853893-25-1C26H23NO5
![9-(4-Fluorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H20FNO4, CAS 853892-92-9](/s/PXYOGWFHUSGTGE-UHFFFAOYSA-N.svg)
9-(4-Fluorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853892-92-9C25H20FNO4
![9-[(2-Methoxyphenyl)methyl]-4-phenyl-8,10-dihydropyrano[2,3-f][1,3]benzoxazin-2-one chemical structure, C25H21NO4, CAS 853893-07-9](/s/GYOOUJPDGXYXCL-UHFFFAOYSA-N.svg)
9-[(2-Methoxyphenyl)methyl]-4-phenyl-8,10-dihydropyrano[2,3-f][1,3]benzoxazin-2-one
CAS 853893-07-9C25H21NO4
![4-(4-Methoxyphenyl)-9-(4-methylbenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C26H23NO4, CAS 853892-89-4](/s/IQMXCCHXPDJYOG-UHFFFAOYSA-N.svg)
4-(4-Methoxyphenyl)-9-(4-methylbenzyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853892-89-4C26H23NO4
![9-[(2,4-Dimethoxyphenyl)methyl]-4-(4-methoxyphenyl)-8,10-dihydropyrano[2,3-f][1,3]benzoxazin-2-one chemical structure, C27H25NO6, CAS 859128-24-8](/s/XQOPAQGYKRZKRA-UHFFFAOYSA-N.svg)
9-[(2,4-Dimethoxyphenyl)methyl]-4-(4-methoxyphenyl)-8,10-dihydropyrano[2,3-f][1,3]benzoxazin-2-one
CAS 859128-24-8C27H25NO6
![9-(2-Chlorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H20ClNO4, CAS 853893-02-4](/s/DYPWRXIISCMQPM-UHFFFAOYSA-N.svg)
9-(2-Chlorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 853893-02-4C25H20ClNO4
![9-(2-Fluorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H20FNO4, CAS 859111-20-9](/s/VWXXUNQLCXBUNZ-UHFFFAOYSA-N.svg)
9-(2-Fluorobenzyl)-4-(4-methoxyphenyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 859111-20-9C25H20FNO4
![6-Chloro-9-(3,4-dimethoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C26H22ClNO5, CAS 849914-29-0](/s/QANAPZVUONELND-UHFFFAOYSA-N.svg)
6-Chloro-9-(3,4-dimethoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 849914-29-0C26H22ClNO5
![6-Chloro-9-(4-methoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C25H20ClNO4, CAS 848755-19-1](/s/OILFIMDHWRODSN-UHFFFAOYSA-N.svg)
6-Chloro-9-(4-methoxybenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 848755-19-1C25H20ClNO4
![9-(2-Chlorobenzyl)-6-ethyl-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C26H22ClNO3, CAS 848868-36-0](/s/HQZQEEUCHDAONL-UHFFFAOYSA-N.svg)
9-(2-Chlorobenzyl)-6-ethyl-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 848868-36-0C26H22ClNO3
![4-(4-Methoxyphenyl)-9-(1-phenylethyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C26H23NO4, CAS 859109-60-7](/s/VWERTOHTHJYPOQ-UHFFFAOYSA-N.svg)
4-(4-Methoxyphenyl)-9-(1-phenylethyl)-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 859109-60-7C26H23NO4
![9-(2-Chlorobenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C24H18ClNO3, CAS 844656-06-0](/s/ANKRLMZQWCJMEZ-UHFFFAOYSA-N.svg)
9-(2-Chlorobenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 844656-06-0C24H18ClNO3
![6-Ethyl-9-(4-methylbenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one chemical structure, C27H25NO3, CAS 877783-88-5](/s/DMEIMJVJUQKSFO-UHFFFAOYSA-N.svg)
6-Ethyl-9-(4-methylbenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one
CAS 877783-88-5C27H25NO3
- 6-Ethyl-9-(4-fluorobenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one845663-15-2C26H22FNO3
- 9-(4-Fluorobenzyl)-4-phenyl-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-2-one848684-34-4C24H18FNO3
- 6-Chloro-4-phenyl-9-[(3,4,5-trimethoxyphenyl)methyl]-8,10-dihydropyrano[2,3-f][1,3]benzoxazin-2-one877796-02-6C27H24ClNO6