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Murcko scaffold

N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide scaffold

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(CSc1nccn1-c1ccccc1)Nc1ccc2c(c1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide page
Murcko scaffold O=C(CSc1nccn1-c1ccccc1)Nc1ccc2c(c1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-{[1-(3,5-dimethylphenyl)-1H-imidazol-2-yl]sulfanyl}acetamide chemical structure, C21H21N3O3S, CAS 851132-01-9
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-{[1-(3,5-dimethylphenyl)-1H-imidazol-2-yl]sulfanyl}acetamide
CAS 851132-01-9C21H21N3O3S
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C20H19N3O3S, CAS 851131-13-0
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide
CAS 851131-13-0C20H19N3O3S
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(3-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C20H19N3O4S, CAS 688335-72-0
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(3-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide
CAS 688335-72-0C20H19N3O4S
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(4-fluorophenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C19H16FN3O3S, CAS 688336-82-5
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(4-fluorophenyl)-1H-imidazol-2-yl)thio)acetamide
CAS 688336-82-5C19H16FN3O3S
2-[1-(4-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C19H16ClN3O3S, CAS 688337-22-6
2-[1-(4-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 688337-22-6C19H16ClN3O3S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-[1-(4-methoxyphenyl)imidazol-2-yl]sulfanylacetamide chemical structure, C20H19N3O4S, CAS 688335-96-8
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-[1-(4-methoxyphenyl)imidazol-2-yl]sulfanylacetamide
CAS 688335-96-8C20H19N3O4S
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C19H17N3O3S, CAS 688335-35-5
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-35-5C19H17N3O3S
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(2,3-dimethylphenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C21H21N3O3S, CAS 851131-58-3
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(2,3-dimethylphenyl)-1H-imidazol-2-yl)thio)acetamide
CAS 851131-58-3C21H21N3O3S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-[1-(4-ethoxyphenyl)imidazol-2-yl]sulfanylacetamide chemical structure, C21H21N3O4S, CAS 688336-40-5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-[1-(4-ethoxyphenyl)imidazol-2-yl]sulfanylacetamide
CAS 688336-40-5C21H21N3O4S
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(4-nitrophenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C19H16N4O5S, CAS 851079-53-3
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(4-nitrophenyl)-1H-imidazol-2-yl)thio)acetamide
CAS 851079-53-3C19H16N4O5S
2-[1-(3-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C19H16ClN3O3S, CAS 851078-95-0
2-[1-(3-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 851078-95-0C19H16ClN3O3S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-[1-(2-methoxyphenyl)imidazol-2-yl]sulfanylacetamide chemical structure, C20H19N3O4S, CAS 893381-15-2
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-[1-(2-methoxyphenyl)imidazol-2-yl]sulfanylacetamide
CAS 893381-15-2C20H19N3O4S
2-[1-(2,6-Diethylphenyl)imidazol-2-yl]sulfanyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide chemical structure, C23H25N3O3S, CAS 893378-15-9
2-[1-(2,6-Diethylphenyl)imidazol-2-yl]sulfanyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
CAS 893378-15-9C23H25N3O3S
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C20H16F3N3O3S, CAS 893391-72-5
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)thio)acetamide
CAS 893391-72-5C20H16F3N3O3S