Murcko scaffold
2-(Benzoylamino)-N-(tetrahydrofuran-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide scaffold
19 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 19
- With full pages
- 6
Scaffold SMILES
O=C(Nc1sc2c(c1C(=O)NCC1CCCO1)CCCC2)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 19 of 19 chemicals
![2-(3-Nitrobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C21H23N3O5S, CAS 378218-29-2](/s/PVRGYCALBXNRTD-UHFFFAOYSA-N.svg)
2-(3-Nitrobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 378218-29-2C21H23N3O5S
![2-(2-Nitrobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C21H23N3O5S, CAS 381680-10-0](/s/KCEKLXUYQLMUCD-UHFFFAOYSA-N.svg)
2-(2-Nitrobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 381680-10-0C21H23N3O5S
![2-[(4-tert-Butylbenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C25H32N2O3S, CAS 380155-00-0](/s/IBHAFBRJWVXJFS-UHFFFAOYSA-N.svg)
2-[(4-tert-Butylbenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 380155-00-0C25H32N2O3S
![2-(2-Bromobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C21H23BrN2O3S, CAS 380559-94-4](/s/CCHAGWIDCADGOV-UHFFFAOYSA-N.svg)
2-(2-Bromobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 380559-94-4C21H23BrN2O3S
![2-[(3-Methoxybenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C22H26N2O4S, CAS 381180-86-5](/s/UADHEAKSDPAAFC-UHFFFAOYSA-N.svg)
2-[(3-Methoxybenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 381180-86-5C22H26N2O4S
![2-(4-Ethoxybenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C23H28N2O4S, CAS 432016-26-7](/s/TXOLFLCPXRFMAI-UHFFFAOYSA-N.svg)
2-(4-Ethoxybenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 432016-26-7C23H28N2O4S
![2-[(4-Chlorobenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C21H23ClN2O3S, CAS 381703-16-8](/s/ASDMHJRPXDESLM-UHFFFAOYSA-N.svg)
2-[(4-Chlorobenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 381703-16-8C21H23ClN2O3S
![2-(2,4-Dichlorobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C21H22Cl2N2O3S, CAS 378221-12-6](/s/MLDDBVHAKFHWPP-UHFFFAOYSA-N.svg)
2-(2,4-Dichlorobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 378221-12-6C21H22Cl2N2O3S
![2-(4-Nitrobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C21H23N3O5S, CAS 381170-85-0](/s/YVCPYIDLYRXWFO-UHFFFAOYSA-N.svg)
2-(4-Nitrobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 381170-85-0C21H23N3O5S
![2-(2-Methoxybenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C22H26N2O4S, CAS 381703-29-3](/s/HGNPHNYYJCJOGY-UHFFFAOYSA-N.svg)
2-(2-Methoxybenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 381703-29-3C22H26N2O4S
![2-(2-Methylbenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C22H26N2O3S, CAS 380579-00-0](/s/HZHQJHODXLPTLC-UHFFFAOYSA-N.svg)
2-(2-Methylbenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 380579-00-0C22H26N2O3S
![2-{[(4-Methoxyphenyl)carbonyl]amino}-N-(tetrahydrofuran-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C22H26N2O4S, CAS 378778-86-0](/s/MTEMPCFCSJVXKL-UHFFFAOYSA-N.svg)
2-{[(4-Methoxyphenyl)carbonyl]amino}-N-(tetrahydrofuran-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 378778-86-0C22H26N2O4S
![2-(3,4-Dimethoxybenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C23H28N2O5S, CAS 380875-00-3](/s/YKJBOWXHCIUTBG-UHFFFAOYSA-N.svg)
2-(3,4-Dimethoxybenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 380875-00-3C23H28N2O5S
![N-(Tetrahydro-2-furanylmethyl)-2-[(3,4,5-trimethoxybenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C24H30N2O6S, CAS 380881-13-0](/s/MDGSRRZINJQMRU-UHFFFAOYSA-N.svg)
N-(Tetrahydro-2-furanylmethyl)-2-[(3,4,5-trimethoxybenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 380881-13-0C24H30N2O6S
![2-[(2-Fluorobenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C21H23FN2O3S, CAS 378762-66-4](/s/BVQQEFHMRLSSHZ-UHFFFAOYSA-N.svg)
2-[(2-Fluorobenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 378762-66-4C21H23FN2O3S
![2-[(2-Chlorobenzoyl)amino]-N-(tetrahydro-2-furanylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C21H23ClN2O3S, CAS 378758-50-0](/s/LNVRYBIAVPJSIL-UHFFFAOYSA-N.svg)
2-[(2-Chlorobenzoyl)amino]-N-(tetrahydro-2-furanylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 378758-50-0C21H23ClN2O3S
2-(Benzoylamino)-N-(tetrahydrofuran-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 380879-75-4C21H24N2O3S
![2-[(4-Bromobenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C21H23BrN2O3S, CAS 383370-15-8](/s/OBQDJYORCWXEHQ-UHFFFAOYSA-N.svg)
2-[(4-Bromobenzoyl)amino]-N-(oxolan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 383370-15-8C21H23BrN2O3S
![2-(4-Fluorobenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C21H23FN2O3S, CAS 381181-05-1](/s/LENFMRHCNQEGRB-UHFFFAOYSA-N.svg)
2-(4-Fluorobenzamido)-N-[(oxolan-2-yl)methyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 381181-05-1C21H23FN2O3S
Related scaffolds
Same ring framework with different atoms or bond orders
