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Murcko scaffold

Ring system with 4 rings and 30 atoms

108 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
108
With full pages
46
Scaffold SMILES

O=C(CSc1nnc(COc2ccccc2)n1-c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(COc2ccccc2)n1-c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 108 chemicals

N-(3,5-Dimethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C26H26N4O3S, CAS 332912-52-4
N-(3,5-Dimethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-52-4C26H26N4O3S
N-(4-Ethoxyphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C26H26N4O4S, CAS 332912-55-7
N-(4-Ethoxyphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-55-7C26H26N4O4S
N-(2,3-Dimethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C26H26N4O3S, CAS 332912-60-4
N-(2,3-Dimethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-60-4C26H26N4O3S
2-((5-((4-Methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide chemical structure, C25H24N4O4S, CAS 332912-61-5
2-((5-((4-Methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide
CAS 332912-61-5C25H24N4O4S
2-((5-((4-Methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(o-tolyl)acetamide chemical structure, C25H24N4O3S, CAS 332912-70-6
2-((5-((4-Methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(o-tolyl)acetamide
CAS 332912-70-6C25H24N4O3S
N-(4-Acetylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C26H24N4O4S, CAS 332912-72-8
N-(4-Acetylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-72-8C26H24N4O4S
N-(5-Chloro-2-methoxyphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C25H23ClN4O4S, CAS 332912-73-9
N-(5-Chloro-2-methoxyphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-73-9C25H23ClN4O4S
N-(5-Chloro-2-methylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C25H23ClN4O3S, CAS 332912-74-0
N-(5-Chloro-2-methylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-74-0C25H23ClN4O3S
N-(3-Chloro-2-methylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C25H23ClN4O3S, CAS 332912-76-2
N-(3-Chloro-2-methylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-76-2C25H23ClN4O3S
N-(2,6-Diethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C28H30N4O3S, CAS 332912-78-4
N-(2,6-Diethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-78-4C28H30N4O3S
2-((5-((4-Methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C25H21F3N4O3S, CAS 332912-81-9
2-((5-((4-Methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide
CAS 332912-81-9C25H21F3N4O3S
N-(2,5-Dimethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C26H26N4O3S, CAS 332912-83-1
N-(2,5-Dimethylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-83-1C26H26N4O3S
N-(2-Ethyl-6-methylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C27H28N4O3S, CAS 332912-84-2
N-(2-Ethyl-6-methylphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 332912-84-2C27H28N4O3S
N-(2-Methoxyphenyl)-2-({5-[(4-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide chemical structure, C25H24N4O3S, CAS 332871-90-6
N-(2-Methoxyphenyl)-2-({5-[(4-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide
CAS 332871-90-6C25H24N4O3S
2-({5-[(4-Cyanophenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(2,6-diethylphenyl)acetamide chemical structure, C28H27N5O2S, CAS 482642-36-4
2-({5-[(4-Cyanophenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(2,6-diethylphenyl)acetamide
CAS 482642-36-4C28H27N5O2S
N-(3-Acetylphenyl)-2-({5-[(2-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide chemical structure, C26H24N4O3S, CAS 335220-31-0
N-(3-Acetylphenyl)-2-({5-[(2-methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide
CAS 335220-31-0C26H24N4O3S
N-(4-Ethoxyphenyl)-2-((5-(phenoxymethyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C26H26N4O3S, CAS 333322-66-0
N-(4-Ethoxyphenyl)-2-((5-(phenoxymethyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 333322-66-0C26H26N4O3S
N-(4-Acetylphenyl)-2-({5-[(4-bromophenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide chemical structure, C25H21BrN4O3S, CAS 482651-46-7
N-(4-Acetylphenyl)-2-({5-[(4-bromophenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetamide
CAS 482651-46-7C25H21BrN4O3S
2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-phenylacetamide chemical structure, C23H19ClN4O2S, CAS 131942-87-5
2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-phenylacetamide
CAS 131942-87-5C23H19ClN4O2S
N-(4-Acetylphenyl)-2-[[5-(phenoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C25H22N4O3S, CAS 131942-78-4
N-(4-Acetylphenyl)-2-[[5-(phenoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 131942-78-4C25H22N4O3S
N-(2,4-Dimethylphenyl)-2-[[4-(4-methylphenyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C26H26N4O2S, CAS 333322-65-9
N-(2,4-Dimethylphenyl)-2-[[4-(4-methylphenyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 333322-65-9C26H26N4O2S
2-({5-[(4-Cyanophenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(2,3-dimethylphenyl)acetamide chemical structure, C26H23N5O2S, CAS 333305-52-5
2-({5-[(4-Cyanophenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(2,3-dimethylphenyl)acetamide
CAS 333305-52-5C26H23N5O2S
2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxyphenyl)acetamide chemical structure, C24H21ClN4O3S, CAS 332948-44-4
2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxyphenyl)acetamide
CAS 332948-44-4C24H21ClN4O3S
2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dimethylphenyl)acetamide chemical structure, C25H23ClN4O2S, CAS 332948-47-7
2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dimethylphenyl)acetamide
CAS 332948-47-7C25H23ClN4O2S