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Murcko scaffold

Ring system with 4 rings and 32 atoms

24 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
32
Chemicals
24
With full pages
19
Scaffold SMILES

O=C(COc1ccc2ccccc2c1)NN=Cc1ccc(OC(=O)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccc2ccccc2c1)NN=Cc1ccc(OC(=O)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-Methoxy-4-((E)-{[2-(2-naphthyloxy)propanoyl]hydrazono}methyl)phenyl 3-bromobenzoate chemical structure, C28H23BrN2O5, CAS 477729-57-0
2-Methoxy-4-((E)-{[2-(2-naphthyloxy)propanoyl]hydrazono}methyl)phenyl 3-bromobenzoate
CAS 477729-57-0C28H23BrN2O5
4-(2-((2-Naphthyloxy)acetyl)carbohydrazonoyl)phenyl 3-bromobenzoate chemical structure, C26H19BrN2O4, CAS 303086-25-1
4-(2-((2-Naphthyloxy)acetyl)carbohydrazonoyl)phenyl 3-bromobenzoate
CAS 303086-25-1C26H19BrN2O4
4-[(E)-({[(1-Bromo-2-naphthyl)oxy]acetyl}hydrazono)methyl]-2-methoxyphenyl 3-bromobenzoate chemical structure, C27H20Br2N2O5, CAS 477729-55-8
4-[(E)-({[(1-Bromo-2-naphthyl)oxy]acetyl}hydrazono)methyl]-2-methoxyphenyl 3-bromobenzoate
CAS 477729-55-8C27H20Br2N2O5
4-(2-((2-Naphthyloxy)acetyl)carbohydrazonoyl)phenyl 2-iodobenzoate chemical structure, C26H19IN2O4, CAS 303085-90-7
4-(2-((2-Naphthyloxy)acetyl)carbohydrazonoyl)phenyl 2-iodobenzoate
CAS 303085-90-7C26H19IN2O4
2-Methoxy-4-(2-((2-naphthyloxy)acetyl)carbohydrazonoyl)phenyl 3-bromobenzoate chemical structure, C27H21BrN2O5, CAS 477728-69-1
2-Methoxy-4-(2-((2-naphthyloxy)acetyl)carbohydrazonoyl)phenyl 3-bromobenzoate
CAS 477728-69-1C27H21BrN2O5
2-Methoxy-4-(2-((2-naphthyloxy)acetyl)carbohydrazonoyl)phenyl benzoate chemical structure, C27H22N2O5, CAS 303086-27-3
2-Methoxy-4-(2-((2-naphthyloxy)acetyl)carbohydrazonoyl)phenyl benzoate
CAS 303086-27-3C27H22N2O5
4-(2-(((1-BR-2-Naphthyl)oxy)AC)carbohydrazonoyl)-2-meo-PH 4-propoxybenzoate chemical structure, C30H27BrN2O6, CAS 767334-07-6
4-(2-(((1-BR-2-Naphthyl)oxy)AC)carbohydrazonoyl)-2-meo-PH 4-propoxybenzoate
CAS 767334-07-6C30H27BrN2O6
4-(2-(((1-BR-2-Naphthyl)oxy)AC)carbohydrazonoyl)-2-ethoxyphenyl 4-chlorobenzoate chemical structure, C28H22BrClN2O5, CAS 767333-99-3
4-(2-(((1-BR-2-Naphthyl)oxy)AC)carbohydrazonoyl)-2-ethoxyphenyl 4-chlorobenzoate
CAS 767333-99-3C28H22BrClN2O5
4-((E)-{2-[2-(2-Naphthyloxy)propanoyl]hydrazono}methyl)phenyl 2-bromobenzoate chemical structure, C27H21BrN2O4, CAS 767333-84-6
4-((E)-{2-[2-(2-Naphthyloxy)propanoyl]hydrazono}methyl)phenyl 2-bromobenzoate
CAS 767333-84-6C27H21BrN2O4
4-[(E)-({[(1-Bromo-2-naphthyl)oxy]acetyl}hydrazono)methyl]-2-ethoxyphenyl 4-methoxybenzoate chemical structure, C29H25BrN2O6, CAS 767332-77-4
4-[(E)-({[(1-Bromo-2-naphthyl)oxy]acetyl}hydrazono)methyl]-2-ethoxyphenyl 4-methoxybenzoate
CAS 767332-77-4C29H25BrN2O6
2-Meo-4-(2-(2-(2-naphthyloxy)propanoyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C30H28N2O6, CAS 765907-71-9
2-Meo-4-(2-(2-(2-naphthyloxy)propanoyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 765907-71-9C30H28N2O6
2-Ethoxy-4-(2-(2-(2-naphthyloxy)propanoyl)carbohydrazonoyl)PH 4-methoxybenzoate chemical structure, C30H28N2O6, CAS 765311-41-9
2-Ethoxy-4-(2-(2-(2-naphthyloxy)propanoyl)carbohydrazonoyl)PH 4-methoxybenzoate
CAS 765311-41-9C30H28N2O6
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C26H18Br2N2O4, CAS 765291-66-5
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 765291-66-5C26H18Br2N2O4
4-[(E)-({[(1-Bromo-2-naphthyl)oxy]acetyl}hydrazono)methyl]-2-ethoxyphenyl 4-ethoxybenzoate chemical structure, C30H27BrN2O6, CAS 765278-15-7
4-[(E)-({[(1-Bromo-2-naphthyl)oxy]acetyl}hydrazono)methyl]-2-ethoxyphenyl 4-ethoxybenzoate
CAS 765278-15-7C30H27BrN2O6
2-Methoxy-4-(2-(2-(2-naphthyloxy)propanoyl)carbohydrazonoyl)phenyl 2-CL-benzoate chemical structure, C28H23ClN2O5, CAS 880053-79-2
2-Methoxy-4-(2-(2-(2-naphthyloxy)propanoyl)carbohydrazonoyl)phenyl 2-CL-benzoate
CAS 880053-79-2C28H23ClN2O5
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C28H23BrN2O5, CAS 881468-30-0
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 881468-30-0C28H23BrN2O5
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2,4-dichlorobenzoate chemical structure, C27H19BrCl2N2O5, CAS 881463-46-3
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2,4-dichlorobenzoate
CAS 881463-46-3C27H19BrCl2N2O5
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-ethoxyphenyl 2,4-dichlorobenzoate chemical structure, C28H21BrCl2N2O5, CAS 882037-74-3
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-ethoxyphenyl 2,4-dichlorobenzoate
CAS 882037-74-3C28H21BrCl2N2O5
4-(2-(2-(2-Naphthyloxy)propanoyl)carbohydrazonoyl)phenyl 3-methylbenzoate chemical structure, C28H24N2O4, CAS 882037-83-4
4-(2-(2-(2-Naphthyloxy)propanoyl)carbohydrazonoyl)phenyl 3-methylbenzoate
CAS 882037-83-4C28H24N2O4
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-ethoxyphenyl benzoate chemical structure, C28H23BrN2O5, CAS 881460-10-2
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-ethoxyphenyl benzoate
CAS 881460-10-2C28H23BrN2O5
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 3-methylbenzoate chemical structure, C27H21BrN2O4, CAS 882037-86-7
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 3-methylbenzoate
CAS 882037-86-7C27H21BrN2O4
4-(2-(((1-BR-2-Naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate chemical structure, C28H23BrN2O6, CAS 881468-19-5
4-(2-(((1-BR-2-Naphthyl)oxy)acetyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate
CAS 881468-19-5C28H23BrN2O6
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2-chlorobenzoate chemical structure, C27H20BrClN2O5, CAS 881461-84-3
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2-chlorobenzoate
CAS 881461-84-3C27H20BrClN2O5
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-methoxyphenyl 3,4-dichlorobenzoate chemical structure, C27H19BrCl2N2O5, CAS 881464-38-6
4-(2-(((1-Bromo-2-naphthyl)oxy)acetyl)carbohydrazonoyl)-2-methoxyphenyl 3,4-dichlorobenzoate
CAS 881464-38-6C27H19BrCl2N2O5