Murcko scaffold
Ring system with 4 rings and 24 atoms
16 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 24
- Chemicals
- 16
- With full pages
- 4
Scaffold SMILES
O=c1c2ccsc2nc(SCc2ccccc2)n1Cc1ccco1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 16 of 16 chemicals
![3-(Furan-2-ylmethyl)-2-[(3-methoxybenzyl)sulfanyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C21H20N2O3S2, CAS 585562-82-9](/s/DUXAMELAIUENOI-UHFFFAOYSA-N.svg)
3-(Furan-2-ylmethyl)-2-[(3-methoxybenzyl)sulfanyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 585562-82-9C21H20N2O3S2
![2-[(3-Fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H17FN2O2S2, CAS 679414-21-2](/s/RSBLCIVJKURHEW-UHFFFAOYSA-N.svg)
2-[(3-Fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 679414-21-2C20H17FN2O2S2
![2-[(2,6-Dichlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H16Cl2N2O2S2, CAS 577698-85-2](/s/SWEYMISGPWCXIP-UHFFFAOYSA-N.svg)
2-[(2,6-Dichlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 577698-85-2C20H16Cl2N2O2S2
![2-[(2-Fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H17FN2O2S2, CAS 585553-84-0](/s/DGFZBXSXXYUFFD-UHFFFAOYSA-N.svg)
2-[(2-Fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 585553-84-0C20H17FN2O2S2
![3-(2-Furanylmethyl)-5,6-dimethyl-2-[(3-methylphenyl)methylthio]-4-thieno[2,3-d]pyrimidinone chemical structure, C21H20N2O2S2, CAS 578732-30-6](/s/ZYGAMWVVETZRIU-UHFFFAOYSA-N.svg)
3-(2-Furanylmethyl)-5,6-dimethyl-2-[(3-methylphenyl)methylthio]-4-thieno[2,3-d]pyrimidinone
CAS 578732-30-6C21H20N2O2S2
![2-[(2-Chloro-6-fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H16ClFN2O2S2, CAS 578736-76-2](/s/QMQBVSWSBLJOGG-UHFFFAOYSA-N.svg)
2-[(2-Chloro-6-fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 578736-76-2C20H16ClFN2O2S2
![3-(Furan-2-ylmethyl)-5,6-dimethyl-2-[(4-methylphenyl)methylsulfanyl]thieno[2,3-d]pyrimidin-4-one chemical structure, C21H20N2O2S2, CAS 587001-74-9](/s/MCDPGNLMBKPHRA-UHFFFAOYSA-N.svg)
3-(Furan-2-ylmethyl)-5,6-dimethyl-2-[(4-methylphenyl)methylsulfanyl]thieno[2,3-d]pyrimidin-4-one
CAS 587001-74-9C21H20N2O2S2
![2-[(4-Fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H17FN2O2S2, CAS 678540-23-3](/s/GVMZISOLMKGAQH-UHFFFAOYSA-N.svg)
2-[(4-Fluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 678540-23-3C20H17FN2O2S2
![2-[(3,4-Dichlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H16Cl2N2O2S2, CAS 678559-38-1](/s/DEUHOVCMGRNFAU-UHFFFAOYSA-N.svg)
2-[(3,4-Dichlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 678559-38-1C20H16Cl2N2O2S2
![3-(Furan-2-ylmethyl)-5,6-dimethyl-2-[(2-methylbenzyl)sulfanyl]thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C21H20N2O2S2, CAS 577762-07-3](/s/HUDUOQGQUHOORK-UHFFFAOYSA-N.svg)
3-(Furan-2-ylmethyl)-5,6-dimethyl-2-[(2-methylbenzyl)sulfanyl]thieno[2,3-d]pyrimidin-4(3H)-one
CAS 577762-07-3C21H20N2O2S2
![2-Benzylsulfanyl-3-furan-2-ylmethyl-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one chemical structure, C20H18N2O2S2, CAS 577767-49-8](/s/HRTCPCIIDTYPMG-UHFFFAOYSA-N.svg)
2-Benzylsulfanyl-3-furan-2-ylmethyl-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one
CAS 577767-49-8C20H18N2O2S2
![2-[(2,6-Difluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H16F2N2O2S2, CAS 573929-92-7](/s/KHRHTEVUICEIHI-UHFFFAOYSA-N.svg)
2-[(2,6-Difluorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 573929-92-7C20H16F2N2O2S2
![2-[(3-Chlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H17ClN2O2S2, CAS 681005-93-6](/s/IWPFLLFDRHCUNZ-UHFFFAOYSA-N.svg)
2-[(3-Chlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 681005-93-6C20H17ClN2O2S2
![2-[(2-Chlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H17ClN2O2S2, CAS 680994-11-0](/s/JFQHKNZKZVMBOY-UHFFFAOYSA-N.svg)
2-[(2-Chlorobenzyl)sulfanyl]-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 680994-11-0C20H17ClN2O2S2
![Ethyl 2-[(3-fluorophenyl)methylsulfanyl]-3-(furan-2-ylmethyl)-5-methyl-4-oxothieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C22H19FN2O4S2, CAS 450369-97-8](/s/AYKDJVYRRQCRKS-UHFFFAOYSA-N.svg)
Ethyl 2-[(3-fluorophenyl)methylsulfanyl]-3-(furan-2-ylmethyl)-5-methyl-4-oxothieno[2,3-d]pyrimidine-6-carboxylate
CAS 450369-97-8C22H19FN2O4S2
![Ethyl 2-{[(2-chlorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-5-methyl-4-oxo-3H,4H-thieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C22H19ClN2O4S2, CAS 450369-92-3](/s/FLSXBKYDHIOQDB-UHFFFAOYSA-N.svg)
Ethyl 2-{[(2-chlorophenyl)methyl]sulfanyl}-3-[(furan-2-yl)methyl]-5-methyl-4-oxo-3H,4H-thieno[2,3-d]pyrimidine-6-carboxylate
CAS 450369-92-3C22H19ClN2O4S2