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Murcko scaffold

N-(1,3-Thiazol-2-yl)cyclohexanecarboxamide scaffold

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
17
With full pages
6
Scaffold SMILES

O=C(Nc1nccs1)C1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Thiazol-2-yl)cyclohexanecarboxamide page
Murcko scaffold O=C(Nc1nccs1)C1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-[(2-Thiazolylamino)carbonyl]cyclohexanecarboxylic acid chemical structure, C11H14N2O3S, CAS 19692-01-4
2-[(2-Thiazolylamino)carbonyl]cyclohexanecarboxylic acid
CAS 19692-01-4C11H14N2O3S
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexane-1-carboxamide chemical structure, C13H7F11N2O2S, CAS 610262-12-9
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexane-1-carboxamide
CAS 610262-12-9C13H7F11N2O2S
N-(1,3-Thiazol-2-yl)cyclohexanecarboxamide chemical structure, C10H14N2OS, CAS 69212-64-2
N-(1,3-Thiazol-2-yl)cyclohexanecarboxamide
CAS 69212-64-2C10H14N2OS
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)cyclohexanecarboxamide chemical structure, C13H18N2O2S, CAS 296266-15-4
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)cyclohexanecarboxamide
CAS 296266-15-4C13H18N2O2S
Ethyl 2-[(cyclohexylcarbonyl)amino]-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C14H20N2O3S, CAS 313405-80-0
Ethyl 2-[(cyclohexylcarbonyl)amino]-4-methyl-1,3-thiazole-5-carboxylate
CAS 313405-80-0C14H20N2O3S
N-(4,5-Dimethyl-1,3-thiazol-2-yl)cyclohexanecarboxamide chemical structure, C12H18N2OS, CAS 352684-72-1
N-(4,5-Dimethyl-1,3-thiazol-2-yl)cyclohexanecarboxamide
CAS 352684-72-1C12H18N2OS
4-tert-Butyl-N-(1,3-thiazol-2-yl)cyclohexane-1-carboxamide chemical structure, C14H22N2OS, CAS 574707-94-1
4-tert-Butyl-N-(1,3-thiazol-2-yl)cyclohexane-1-carboxamide
CAS 574707-94-1C14H22N2OS
Ethyl 2-(cyclohexanecarboxamido)thiazole-4-carboxylate chemical structure, C13H18N2O3S, CAS 258338-61-3
Ethyl 2-(cyclohexanecarboxamido)thiazole-4-carboxylate
CAS 258338-61-3C13H18N2O3S
2-[(5-Ethoxycarbonyl-4-methyl-1,3-thiazol-2-yl)carbamoyl]cyclohexane-1-carboxylic acid chemical structure, C15H20N2O5S, CAS 354550-91-7
2-[(5-Ethoxycarbonyl-4-methyl-1,3-thiazol-2-yl)carbamoyl]cyclohexane-1-carboxylic acid
CAS 354550-91-7C15H20N2O5S
2-({[4-(2-Ethoxy-2-oxoethyl)-1,3-thiazol-2-yl]amino}carbonyl)cyclohexanecarboxylic acid chemical structure, C15H20N2O5S, CAS 444935-22-2
2-({[4-(2-Ethoxy-2-oxoethyl)-1,3-thiazol-2-yl]amino}carbonyl)cyclohexanecarboxylic acid
CAS 444935-22-2C15H20N2O5S
Ethyl 2-(cyclohexanecarbonylimino)-3,4-dimethyl-1,3-thiazole-5-carboxylate chemical structure, C15H22N2O3S, CAS 476628-26-9
Ethyl 2-(cyclohexanecarbonylimino)-3,4-dimethyl-1,3-thiazole-5-carboxylate
CAS 476628-26-9C15H22N2O3S
2-(2-(Cyclohexanecarboxamido)thiazol-4-yl)acetic acid chemical structure, C12H16N2O3S, CAS 926235-87-2
2-(2-(Cyclohexanecarboxamido)thiazol-4-yl)acetic acid
CAS 926235-87-2C12H16N2O3S
(Trans)-4-aminomethylcyclohexanecarboxylic acid thiazol-2-ylamide,hydrochloride chemical structure, C11H18ClN3OS, CAS 1204337-39-2
(Trans)-4-aminomethylcyclohexanecarboxylic acid thiazol-2-ylamide,hydrochloride
CAS 1204337-39-2C11H18ClN3OS
(Trans)-4-aminomethylcyclohexanecarboxylic acid (5-methylthiazol-2-yl)amide,hydrochloride chemical structure, C12H20ClN3OS, CAS 1204337-41-6
(Trans)-4-aminomethylcyclohexanecarboxylic acid (5-methylthiazol-2-yl)amide,hydrochloride
CAS 1204337-41-6C12H20ClN3OS
(Trans)-4-aminomethyl-cyclohexanecarboxylic acid (4-methyl-thiazol-2-yl)-amide hydrochloride chemical structure, C12H20ClN3OS, CAS 1204337-42-7
(Trans)-4-aminomethyl-cyclohexanecarboxylic acid (4-methyl-thiazol-2-yl)-amide hydrochloride
CAS 1204337-42-7C12H20ClN3OS
4,4-Difluoro-N-(1,3-thiazol-2-yl)cyclohexane-1-carboxamide chemical structure, C10H12F2N2OS, CAS 2329278-33-1
4,4-Difluoro-N-(1,3-thiazol-2-yl)cyclohexane-1-carboxamide
CAS 2329278-33-1C10H12F2N2OS
N-(4,5-Dimethyl-1,3-thiazol-2-yl)-4,4-difluorocyclohexane-1-carboxamide chemical structure, C12H16F2N2OS, CAS 2327065-54-1
N-(4,5-Dimethyl-1,3-thiazol-2-yl)-4,4-difluorocyclohexane-1-carboxamide
CAS 2327065-54-1C12H16F2N2OS