Murcko scaffold
Ring system with 2 rings and 10 atoms
10 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 10
- With full pages
- 3
Scaffold SMILES
O=C1CCCCN1C1CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
3-Bromo-1-cyclopropylpiperidin-2-one
CAS 178946-37-7C8H12BrNO
1-Cyclopropyl-6-oxopiperidine-3-carboxylic acid
CAS 1083246-40-5C9H13NO3
3-Amino-1-cyclopropylpiperidin-2-one
CAS 1343652-40-3C8H14N2O
1-(2-Oxopiperidin-1-yl)cyclopropane-1-carboxylic acid
CAS 1483916-19-3C9H13NO3
1-Cyclopropyl-2-oxo-4-piperidinecarboxylic acid
CAS 1502214-29-0C9H13NO3
1-Cyclopropyl-2-oxopiperidine-3-carboxylic acid
CAS 1512560-07-4C9H13NO3
1-Cyclopropyl-4-hydroxypiperidin-2-one
CAS 1896697-77-0C8H13NO2
1-Cyclopropyl-6-oxopiperidine-3-carboxylic acid hydrochloride
CAS 2243507-64-2C9H14ClNO3
3-Amino-1-cyclopropylpiperidin-2-one hydrochloride
CAS 2551114-53-3C8H15ClN2O
Potassium 1-cyclopropyl-2-oxopiperidine-3-carboxylate
CAS 2613382-62-8C9H12KNO3
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(C2CC2)cc1778 chemicals
c1ccc(C2CO2)cc1108 chemicals
c1ccc(C2CC2)nc182 chemicals
c1cnc(C2CC2)nc163 chemicals
c1cncc(C2CC2)c150 chemicals
c1ccc(C2N=N2)cc135 chemicals
c1cc(C2CC2)ncn126 chemicals
c1cc(C2CC2)ccn124 chemicals
C1CNCC(C2CC2)C115 chemicals
C1CC(C2CC2)CCN115 chemicals
C1CCC(C2CC2)CC115 chemicals
C1CC(C2CC2)CCO111 chemicals