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Murcko scaffold

Isoxazoline scaffold

361 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
361
With full pages
64
Scaffold SMILES

C1=NOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isoxazoline page
Murcko scaffold C1=NOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 361 chemicals

5-Isoxazoleacetic acid, alpha-amino-3-chloro-4,5-dihydro- chemical structure, C5H7ClN2O3, CAS 52583-41-2
5-Isoxazoleacetic acid, alpha-amino-3-chloro-4,5-dihydro-
CAS 52583-41-2C5H7ClN2O3
3-Nitro-4,5-dihydroisoxazole chemical structure, C3H4N2O3, CAS 1121-14-8
3-Nitro-4,5-dihydroisoxazole
CAS 1121-14-8C3H4N2O3
4,5-Dihydro-3-nitroisoxazole-2-oxide chemical structure, C3H4N2O4, CAS 4122-45-6
4,5-Dihydro-3-nitroisoxazole-2-oxide
CAS 4122-45-6C3H4N2O4
Hydroxy acivicin chemical structure, C5H7ClN2O4, CAS 54549-02-9
Hydroxy acivicin
CAS 54549-02-9C5H7ClN2O4
Isoxazole, 4,5-dihydro-3-methoxy- chemical structure, C4H7NO2, CAS 40784-13-2
Isoxazole, 4,5-dihydro-3-methoxy-
CAS 40784-13-2C4H7NO2
1-(5-Tetradecyl-4,5-dihydro-1,2-oxazol-3-yl)pentadecan-1-one chemical structure, C32H61NO2, CAS 65919-76-8
1-(5-Tetradecyl-4,5-dihydro-1,2-oxazol-3-yl)pentadecan-1-one
CAS 65919-76-8C32H61NO2
Acivicin chemical structure, C5H7ClN2O3, CAS 42228-92-2
Acivicin
CAS 42228-92-2C5H7ClN2O3
N-(3-Methoxy-4,5-dihydro-1,2-oxazol-4-yl)acetamide chemical structure, C6H10N2O3, CAS 14617-43-7
N-(3-Methoxy-4,5-dihydro-1,2-oxazol-4-yl)acetamide
CAS 14617-43-7C6H10N2O3
(R)-2-Amino-2-((R)-3-chloro-4,5-dihydroisoxazol-5-yl)acetic acid chemical structure, C5H7ClN2O3, CAS 76898-56-1
(R)-2-Amino-2-((R)-3-chloro-4,5-dihydroisoxazol-5-yl)acetic acid
CAS 76898-56-1C5H7ClN2O3
Methyl 7-(5-acetyl-4,5-dihydro-1,2-oxazol-3-yl)heptanoate chemical structure, C13H21NO4, CAS 82781-81-5
Methyl 7-(5-acetyl-4,5-dihydro-1,2-oxazol-3-yl)heptanoate
CAS 82781-81-5C13H21NO4
Methyl 5-methyl-4,5-dihydroisoxazole-5-carboxylate chemical structure, C6H9NO3, CAS 87046-29-5
Methyl 5-methyl-4,5-dihydroisoxazole-5-carboxylate
CAS 87046-29-5C6H9NO3
4,5-Dihydro-1,2-oxazole-3-carboxylic acid chemical structure, C4H5NO3, CAS 4485-98-7
4,5-Dihydro-1,2-oxazole-3-carboxylic acid
CAS 4485-98-7C4H5NO3
5-(Trifluoromethyl)-4,5-dihydro-1,2-oxazol-5-ol chemical structure, C4H4F3NO2, CAS 134219-67-3
5-(Trifluoromethyl)-4,5-dihydro-1,2-oxazol-5-ol
CAS 134219-67-3C4H4F3NO2
5-Trichloromethyl-4,5-dihydro-5-isoxazolol chemical structure, C4H4Cl3NO2, CAS 34648-11-8
5-Trichloromethyl-4,5-dihydro-5-isoxazolol
CAS 34648-11-8C4H4Cl3NO2
4-(2-Ethoxy-2-oxoethyl)-3,5-bis(ethoxycarbonyl)-4,5-dihydroisoxazole 2-oxide chemical structure, C13H19NO8, CAS 362601-40-9
4-(2-Ethoxy-2-oxoethyl)-3,5-bis(ethoxycarbonyl)-4,5-dihydroisoxazole 2-oxide
CAS 362601-40-9C13H19NO8
3,5-Bis(ethoxycarbonyl)-4-(2-oxopropyl)-4,5-dihydroisoxazole 2-oxide chemical structure, C12H17NO7, CAS 332898-58-5
3,5-Bis(ethoxycarbonyl)-4-(2-oxopropyl)-4,5-dihydroisoxazole 2-oxide
CAS 332898-58-5C12H17NO7
(3-tert-Butyl-4,5-dihydro-1,2-oxazol-5-yl)phosphonic acid chemical structure, C7H14NO4P, CAS 125674-52-4
(3-tert-Butyl-4,5-dihydro-1,2-oxazol-5-yl)phosphonic acid
CAS 125674-52-4C7H14NO4P
Phosphonic acid, (4,5-dihydro-3-propyl-5-isoxazolyl)-, diammonium salt chemical structure, C6H18N3O4P, CAS 125674-63-7
Phosphonic acid, (4,5-dihydro-3-propyl-5-isoxazolyl)-, diammonium salt
CAS 125674-63-7C6H18N3O4P
Phosphinic acid, (3-(1,1-dimethylethyl)-4,5-dihydro-5-isoxazolyl)methyl- chemical structure, C8H16NO3P, CAS 125674-79-5
Phosphinic acid, (3-(1,1-dimethylethyl)-4,5-dihydro-5-isoxazolyl)methyl-
CAS 125674-79-5C8H16NO3P
4-(2-Methoxy-2-oxoethyl)-3,5-bis(methoxycarbonyl)-4,5-dihydroisoxazole 2-oxide chemical structure, C10H13NO8, CAS 53183-90-7
4-(2-Methoxy-2-oxoethyl)-3,5-bis(methoxycarbonyl)-4,5-dihydroisoxazole 2-oxide
CAS 53183-90-7C10H13NO8
5-(tert-Butyl)-3-methyl-4,5-dihydroisoxazol-5-ol chemical structure, C8H15NO2, CAS 53009-15-7
5-(tert-Butyl)-3-methyl-4,5-dihydroisoxazol-5-ol
CAS 53009-15-7C8H15NO2
3-Methyl-5-(trifluoromethyl)-4,5-dihydroisoxazol-5-ol chemical structure, C5H6F3NO2, CAS 51479-84-6
3-Methyl-5-(trifluoromethyl)-4,5-dihydroisoxazol-5-ol
CAS 51479-84-6C5H6F3NO2
Ethyl 3-chloro-5-methyl-4,5-dihydro-1,2-oxazole-4-carboxylate chemical structure, C7H10ClNO3, CAS 201138-38-7
Ethyl 3-chloro-5-methyl-4,5-dihydro-1,2-oxazole-4-carboxylate
CAS 201138-38-7C7H10ClNO3
(3-Methyl-4,5-dihydro-1,2-oxazol-5-yl)methanamine chemical structure, C5H10N2O, CAS 959311-13-8
(3-Methyl-4,5-dihydro-1,2-oxazol-5-yl)methanamine
CAS 959311-13-8C5H10N2O