CompoundList
Sign in
Murcko scaffold

1,4-Dihydro-1,6-naphthyridin-4-one scaffold

39 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
39
With full pages
3
Scaffold SMILES

O=c1cc[nH]c2ccncc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Dihydro-1,6-naphthyridin-4-one page
Murcko scaffold O=c1cc[nH]c2ccncc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

1,4-Dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acid chemical structure, C9H6N2O3, CAS 4901-94-4
1,4-Dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acid
CAS 4901-94-4C9H6N2O3
3-Chloro-[1,6]naphthyridin-4-ol chemical structure, C8H5ClN2O, CAS 53454-33-4
3-Chloro-[1,6]naphthyridin-4-ol
CAS 53454-33-4C8H5ClN2O
1-Propyl-5-(trifluoromethyl)-1,6-naphthyridin-4-one chemical structure, C12H11F3N2O, CAS 341936-93-4
1-Propyl-5-(trifluoromethyl)-1,6-naphthyridin-4-one
CAS 341936-93-4C12H11F3N2O
1-Butyl-5-(trifluoromethyl)-1,6-naphthyridin-4(1H)-one chemical structure, C13H13F3N2O, CAS 161014-23-9
1-Butyl-5-(trifluoromethyl)-1,6-naphthyridin-4(1H)-one
CAS 161014-23-9C13H13F3N2O
1,4-Dihydro-1,6-naphthyridin-4-one chemical structure, C8H6N2O, CAS 72754-01-9
1,4-Dihydro-1,6-naphthyridin-4-one
CAS 72754-01-9C8H6N2O
8-Bromo-1,6-naphthyridin-4-ol chemical structure, C8H5BrN2O, CAS 72754-03-1
8-Bromo-1,6-naphthyridin-4-ol
CAS 72754-03-1C8H5BrN2O
5-Chloro-1,4-dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acid ethyl ester chemical structure, C11H9ClN2O3, CAS 83785-77-7
5-Chloro-1,4-dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acid ethyl ester
CAS 83785-77-7C11H9ClN2O3
[1,6]Naphthyridin-4(1H)-one, 1-(3-methoxypropyl)-5-(trifluoromethyl)- chemical structure, C13H13F3N2O2, CAS 924839-18-9
[1,6]Naphthyridin-4(1H)-one, 1-(3-methoxypropyl)-5-(trifluoromethyl)-
CAS 924839-18-9C13H13F3N2O2
Ethyl 4-hydroxy-1,6-naphthyridine-3-carboxylate chemical structure, C11H10N2O3, CAS 6861-83-2
Ethyl 4-hydroxy-1,6-naphthyridine-3-carboxylate
CAS 6861-83-2C11H10N2O3
1-Methyl-1,6-naphthyridin-4(1H)-one chemical structure, C9H8N2O, CAS 5268-39-3
1-Methyl-1,6-naphthyridin-4(1H)-one
CAS 5268-39-3C9H8N2O
Methyl 4-oxo-1,4-dihydro-1,6-naphthyridine-3-carboxylate chemical structure, C10H8N2O3, CAS 191287-57-7
Methyl 4-oxo-1,4-dihydro-1,6-naphthyridine-3-carboxylate
CAS 191287-57-7C10H8N2O3
7-Chloro-1,6-naphthyridin-4(1H)-one chemical structure, C8H5ClN2O, CAS 952138-12-4
7-Chloro-1,6-naphthyridin-4(1H)-one
CAS 952138-12-4C8H5ClN2O
5,7-Dichloro-1,6-naphthyridin-4-ol chemical structure, C8H4Cl2N2O, CAS 1443378-52-6
5,7-Dichloro-1,6-naphthyridin-4-ol
CAS 1443378-52-6C8H4Cl2N2O
7-Methoxy-1H-1,6-naphthyridin-4-one chemical structure, C9H8N2O2, CAS 952138-18-0
7-Methoxy-1H-1,6-naphthyridin-4-one
CAS 952138-18-0C9H8N2O2
8-Bromo-7-methoxy-1,6-naphthyridin-4(1H)-one chemical structure, C9H7BrN2O2, CAS 952138-17-9
8-Bromo-7-methoxy-1,6-naphthyridin-4(1H)-one
CAS 952138-17-9C9H7BrN2O2
5-(Dimethylamino)-1H-1,6-naphthyridin-4-one chemical structure, C10H11N3O, CAS 952138-23-7
5-(Dimethylamino)-1H-1,6-naphthyridin-4-one
CAS 952138-23-7C10H11N3O
5-Amino-1-butyl-1,6-naphthyridin-4(1H)-one chemical structure, C12H15N3O, CAS 820976-09-8
5-Amino-1-butyl-1,6-naphthyridin-4(1H)-one
CAS 820976-09-8C12H15N3O
5-Amino-1-ethyl-1,6-naphthyridin-4(1H)-one chemical structure, C10H11N3O, CAS 820976-08-7
5-Amino-1-ethyl-1,6-naphthyridin-4(1H)-one
CAS 820976-08-7C10H11N3O
2-(Trifluoromethyl)-1,6-naphthyridin-4-ol chemical structure, C9H5F3N2O, CAS 1501246-61-2
2-(Trifluoromethyl)-1,6-naphthyridin-4-ol
CAS 1501246-61-2C9H5F3N2O
5-Chloro-1,6-naphthyridin-4(1H)-one chemical structure, C8H5ClN2O, CAS 1018812-98-0
5-Chloro-1,6-naphthyridin-4(1H)-one
CAS 1018812-98-0C8H5ClN2O
4-Hydroxy-1,6-naphthyridine-3-carbonitrile chemical structure, C9H5N3O, CAS 191287-56-6
4-Hydroxy-1,6-naphthyridine-3-carbonitrile
CAS 191287-56-6C9H5N3O
3-Bromo-1,6-naphthyridin-4-ol chemical structure, C8H5BrN2O, CAS 53454-32-3
3-Bromo-1,6-naphthyridin-4-ol
CAS 53454-32-3C8H5BrN2O
8-Methyl-1,6-naphthyridin-4(1H)-one chemical structure, C9H8N2O, CAS 1598566-86-9
8-Methyl-1,6-naphthyridin-4(1H)-one
CAS 1598566-86-9C9H8N2O
3-Iodo-1,4-dihydro-1,6-naphthyridin-4-one chemical structure, C8H5IN2O, CAS 1601078-87-8
3-Iodo-1,4-dihydro-1,6-naphthyridin-4-one
CAS 1601078-87-8C8H5IN2O