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Murcko scaffold

Ring system with 4 rings and 36 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
36
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(CN=Nc1ccccc1)Nc1ccc(-c2ccc(NC(=O)CN=Nc3ccccc3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN=Nc1ccccc1)Nc1ccc(-c2ccc(NC(=O)CN=Nc3ccccc3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Pigment Yellow 16 chemical structure, C34H28Cl4N6O4, CAS 5979-28-2
Pigment Yellow 16
CAS 5979-28-2C34H28Cl4N6O4
N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[2-(5-chloro-2-methylphenyl)diazenyl]-3-oxobutanamide] chemical structure, C36H34Cl2N6O4, CAS 5905-17-9
N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[2-(5-chloro-2-methylphenyl)diazenyl]-3-oxobutanamide]
CAS 5905-17-9C36H34Cl2N6O4
RefChem:117605 chemical structure, C52H76Cl2N12O6, CAS 40948-42-3
RefChem:117605
CAS 40948-42-3C52H76Cl2N12O6
Benzamide, 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis[4-methyl- chemical structure, C38H38N8O6, CAS 64441-14-1
Benzamide, 3,3'-[(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis[4-methyl-
CAS 64441-14-1C38H38N8O6
2,2'-((3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(imino(1-acetyl-2-oxo-2,1-ethanediyl)azo))bis(5-(acetylamino)benzoic) acid chemical structure, C40H38N8O10
2,2'-((3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(imino(1-acetyl-2-oxo-2,1-ethanediyl)azo))bis(5-(acetylamino)benzoic) acid
C40H38N8O10
Benzoic acid, 2,2a(2)-[(3,3a(2)-dimethyl[1,1a(2)-biphenyl]-4,4a(2)-diyl)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)azo]]bis[5-(acetylamino)- chemical structure, C40H38N8O10, CAS 94088-53-6
Benzoic acid, 2,2a(2)-[(3,3a(2)-dimethyl[1,1a(2)-biphenyl]-4,4a(2)-diyl)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)azo]]bis[5-(acetylamino)-
CAS 94088-53-6C40H38N8O10