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Murcko scaffold

Ring system with 2 rings and 15 atoms

62 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
62
With full pages
7
Scaffold SMILES

C(=Cc1ccccc1)CN1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1ccccc1)CN1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

Piperazine, 4-cinnamyl-1-propionyl- chemical structure, C16H22N2O, CAS 17719-88-9
Piperazine, 4-cinnamyl-1-propionyl-
CAS 17719-88-9C16H22N2O
1-Butanone, 1-(4-(3-phenyl-2-propen-1-yl)-1-piperazinyl)-, hydrochloride (1:1) chemical structure, C17H25ClN2O, CAS 17730-82-4
1-Butanone, 1-(4-(3-phenyl-2-propen-1-yl)-1-piperazinyl)-, hydrochloride (1:1)
CAS 17730-82-4C17H25ClN2O
Bucinnazine chemical structure, C17H24N2O, CAS 17719-89-0
Bucinnazine
CAS 17719-89-0C17H24N2O
4-[(E)-3-Phenylprop-2-enyl]-N-propan-2-ylpiperazine-1-carbothioamide chemical structure, C17H25N3S, CAS 485344-84-1
4-[(E)-3-Phenylprop-2-enyl]-N-propan-2-ylpiperazine-1-carbothioamide
CAS 485344-84-1C17H25N3S
1-Cinnamylpiperazine chemical structure, C13H18N2, CAS 18903-01-0
1-Cinnamylpiperazine
CAS 18903-01-0C13H18N2
1-Methylsulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine chemical structure, C14H20N2O2S, CAS 5259-11-0
1-Methylsulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine
CAS 5259-11-0C14H20N2O2S
(E)-4-(3-Phenyl-2-propenyl)-1-piperazineethanol chemical structure, C15H22N2O, CAS 1811-58-1
(E)-4-(3-Phenyl-2-propenyl)-1-piperazineethanol
CAS 1811-58-1C15H22N2O
1-Methyl-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine chemical structure, C14H20N2, CAS 1133842-25-7
1-Methyl-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
CAS 1133842-25-7C14H20N2
N-Ethyl-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C16H23N3S, CAS 433323-39-8
N-Ethyl-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 433323-39-8C16H23N3S
3-Oxo-3-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}propanenitrile chemical structure, C16H19N3O, CAS 543686-58-4
3-Oxo-3-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}propanenitrile
CAS 543686-58-4C16H19N3O
(2E)-4-Oxo-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}but-2-enoic acid chemical structure, C17H20N2O3, CAS 550299-54-2
(2E)-4-Oxo-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}but-2-enoic acid
CAS 550299-54-2C17H20N2O3
Flunarizine impurity 59 chemical structure, C13H18N2, CAS 114312-65-1
Flunarizine impurity 59
CAS 114312-65-1C13H18N2
(3E)-2-(4-[(tert-Butyl)oxycarbonyl]piperazinyl)-4-phenylbut-3-enoic acid chemical structure, C19H26N2O4, CAS 853681-16-0
(3E)-2-(4-[(tert-Butyl)oxycarbonyl]piperazinyl)-4-phenylbut-3-enoic acid
CAS 853681-16-0C19H26N2O4
N-Methyl-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide chemical structure, C15H21N3S, CAS 455294-88-9
N-Methyl-4-[(E)-3-phenylprop-2-enyl]piperazine-1-carbothioamide
CAS 455294-88-9C15H21N3S
4-[(2E)-3-Phenylprop-2-en-1-yl]-N-propylpiperazine-1-carboxamide chemical structure, C17H25N3O, CAS 734480-33-2
4-[(2E)-3-Phenylprop-2-en-1-yl]-N-propylpiperazine-1-carboxamide
CAS 734480-33-2C17H25N3O
(2E)-4,4-Dimethyl-3-oxo-2-[[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methylidene]pentanenitrile chemical structure, C21H27N3O, CAS 1025295-23-1
(2E)-4,4-Dimethyl-3-oxo-2-[[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methylidene]pentanenitrile
CAS 1025295-23-1C21H27N3O
1-[4-[(E)-3-Phenylprop-2-enyl]piperazin-1-yl]hexan-1-one chemical structure, C19H28N2O, CAS 433978-02-0
1-[4-[(E)-3-Phenylprop-2-enyl]piperazin-1-yl]hexan-1-one
CAS 433978-02-0C19H28N2O
Piperazine, 1-cinnamyl-2,6-dimethyl-4-propionyl- chemical structure, C18H26N2O, CAS 4204-00-6
Piperazine, 1-cinnamyl-2,6-dimethyl-4-propionyl-
CAS 4204-00-6C18H26N2O
Piperazine, 4-cinnamyl-2,6-dimethyl-1-propionyl- chemical structure, C18H26N2O, CAS 4204-01-7
Piperazine, 4-cinnamyl-2,6-dimethyl-1-propionyl-
CAS 4204-01-7C18H26N2O
4-Cinnamyl-1-piperazinecarboxamidine chemical structure, C14H20N4, CAS 81746-15-8
4-Cinnamyl-1-piperazinecarboxamidine
CAS 81746-15-8C14H20N4
Piperazine, 1-isobutyryl-4-(phenylallyl)-, hydrochloride chemical structure, C17H25ClN2O, CAS 17730-61-9
Piperazine, 1-isobutyryl-4-(phenylallyl)-, hydrochloride
CAS 17730-61-9C17H25ClN2O
Piperazine, 1-(phenylallyl)-4-valeryl-, hydrochloride chemical structure, C18H27ClN2O, CAS 17730-62-0
Piperazine, 1-(phenylallyl)-4-valeryl-, hydrochloride
CAS 17730-62-0C18H27ClN2O
Piperazine, 1-phenylallyl-4-propionyl-, hydrochloride chemical structure, C16H23ClN2O, CAS 17730-81-3
Piperazine, 1-phenylallyl-4-propionyl-, hydrochloride
CAS 17730-81-3C16H23ClN2O
Piperazine, 1-acetyl-4-(phenylallyl)-, hydrochloride chemical structure, C15H21ClN2O, CAS 18907-69-2
Piperazine, 1-acetyl-4-(phenylallyl)-, hydrochloride
CAS 18907-69-2C15H21ClN2O