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Murcko scaffold

Ring system with 2 rings and 15 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
14
With full pages
4
Scaffold SMILES

O=c1ccnc(C=Cc2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc(C=Cc2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-[2-(3,4-Dimethoxyphenyl)ethenyl]-4-hydroxy-5-nitro-1H-pyrimidin-6-one chemical structure, C14H13N3O6
2-[2-(3,4-Dimethoxyphenyl)ethenyl]-4-hydroxy-5-nitro-1H-pyrimidin-6-one
C14H13N3O6
2-[2-(4-Chlorophenyl)vinyl]-6-hydroxy-5-nitro-4(3H)-pyrimidinone chemical structure, C12H8ClN3O4, CAS 5879-11-8
2-[2-(4-Chlorophenyl)vinyl]-6-hydroxy-5-nitro-4(3H)-pyrimidinone
CAS 5879-11-8C12H8ClN3O4
2-[(Z)-2-(3,5-Dimethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one chemical structure, C14H13N3O6, CAS 797778-13-3
2-[(Z)-2-(3,5-Dimethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one
CAS 797778-13-3C14H13N3O6
6-Hydroxy-2-[(Z)-2-(3-hydroxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one chemical structure, C12H9N3O5, CAS 797778-36-0
6-Hydroxy-2-[(Z)-2-(3-hydroxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one
CAS 797778-36-0C12H9N3O5
2-[(Z)-2-(3,4-Dimethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one chemical structure, C14H13N3O6, CAS 797778-69-9
2-[(Z)-2-(3,4-Dimethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one
CAS 797778-69-9C14H13N3O6
2-[(E)-2-(2,5-Dimethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one chemical structure, C14H13N3O6, CAS 328971-53-5
2-[(E)-2-(2,5-Dimethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one
CAS 328971-53-5C14H13N3O6
2-[(Z)-2-(2,4-Diethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one chemical structure, C16H17N3O6, CAS 797779-12-5
2-[(Z)-2-(2,4-Diethoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one
CAS 797779-12-5C16H17N3O6
6-Hydroxy-2-[(Z)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one chemical structure, C13H11N3O6, CAS 797779-25-0
6-Hydroxy-2-[(Z)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one
CAS 797779-25-0C13H11N3O6
2-[(E)-2-(3-Ethoxy-4-propoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one chemical structure, C17H19N3O6, CAS 797779-27-2
2-[(E)-2-(3-Ethoxy-4-propoxyphenyl)ethenyl]-6-hydroxy-5-nitropyrimidin-4(3H)-one
CAS 797779-27-2C17H19N3O6
2-(3,4-Dimethoxystyryl)-6-hydroxy-5-nitropyrimidin-4(3H)-one chemical structure, C14H13N3O6
2-(3,4-Dimethoxystyryl)-6-hydroxy-5-nitropyrimidin-4(3H)-one
C14H13N3O6
Ethyl 3-{4-hydroxy-6-oxo-2-[(E)-2-phenylethenyl]-1,6-dihydro-5-pyrimidinyl}propanoate chemical structure, C17H18N2O4, CAS 952587-41-6
Ethyl 3-{4-hydroxy-6-oxo-2-[(E)-2-phenylethenyl]-1,6-dihydro-5-pyrimidinyl}propanoate
CAS 952587-41-6C17H18N2O4
Methyl 3-{4-hydroxy-6-oxo-2-[(E)-2-phenylethenyl]-1,6-dihydro-5-pyrimidinyl}propanoate chemical structure, C16H16N2O4, CAS 1003945-85-4
Methyl 3-{4-hydroxy-6-oxo-2-[(E)-2-phenylethenyl]-1,6-dihydro-5-pyrimidinyl}propanoate
CAS 1003945-85-4C16H16N2O4
6-Hydroxy-2-[(Z)-2-(4-hydroxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one chemical structure, C12H9N3O5, CAS 339162-18-4
6-Hydroxy-2-[(Z)-2-(4-hydroxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one
CAS 339162-18-4C12H9N3O5
6-Hydroxy-2-[(Z)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one chemical structure, C13H11N3O6, CAS 392705-97-4
6-Hydroxy-2-[(Z)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-5-nitropyrimidin-4(3H)-one
CAS 392705-97-4C13H11N3O6