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Murcko scaffold

Ring system with 4 rings and 33 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
33
Chemicals
7
With full pages
6
Scaffold SMILES

O=C(NN=Cc1ccccc1OCc1ccccc1)c1ccc(OCc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1OCc1ccccc1)c1ccc(OCc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-[[2-[(2-Nitrophenyl)methoxy]phenyl]methylideneamino]-4-phenylmethoxybenzamide chemical structure, C28H23N3O5, CAS 5794-34-3
N-[[2-[(2-Nitrophenyl)methoxy]phenyl]methylideneamino]-4-phenylmethoxybenzamide
CAS 5794-34-3C28H23N3O5
N'-(2-(Benzyloxy)benzylidene)-4-((4-chlorobenzyl)oxy)benzohydrazide chemical structure, C28H23ClN2O3, CAS 332146-94-8
N'-(2-(Benzyloxy)benzylidene)-4-((4-chlorobenzyl)oxy)benzohydrazide
CAS 332146-94-8C28H23ClN2O3
N'-(2-((4-Bromobenzyl)oxy)benzylidene)-4-((4-chlorobenzyl)oxy)benzohydrazide chemical structure, C28H22BrClN2O3, CAS 350992-43-7
N'-(2-((4-Bromobenzyl)oxy)benzylidene)-4-((4-chlorobenzyl)oxy)benzohydrazide
CAS 350992-43-7C28H22BrClN2O3
N'-(2-(Benzyloxy)benzylidene)-4-((4-methylbenzyl)oxy)benzohydrazide chemical structure, C29H26N2O3, CAS 881461-11-6
N'-(2-(Benzyloxy)benzylidene)-4-((4-methylbenzyl)oxy)benzohydrazide
CAS 881461-11-6C29H26N2O3
Methyl 4-((2-(2-(4-((4-methylbenzyl)oxy)benzoyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C31H28N2O5, CAS 881460-64-6
Methyl 4-((2-(2-(4-((4-methylbenzyl)oxy)benzoyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 881460-64-6C31H28N2O5
N'-(2-(Benzyloxy)-5-bromobenzylidene)-4-((4-chlorobenzyl)oxy)benzohydrazide chemical structure, C28H22BrClN2O3, CAS 881460-57-7
N'-(2-(Benzyloxy)-5-bromobenzylidene)-4-((4-chlorobenzyl)oxy)benzohydrazide
CAS 881460-57-7C28H22BrClN2O3
Methyl 4-((2-(2-(4-((4-chlorobenzyl)oxy)benzoyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C30H25ClN2O5, CAS 881460-08-8
Methyl 4-((2-(2-(4-((4-chlorobenzyl)oxy)benzoyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 881460-08-8C30H25ClN2O5