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Murcko scaffold

Ring system with 3 rings and 22 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(Nc1cccs1)C(Sc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccs1)C(Sc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-phenyl-2-phenylsulfanylacetamide chemical structure, C21H18N2OS2, CAS 312703-95-0
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-2-phenyl-2-phenylsulfanylacetamide
CAS 312703-95-0C21H18N2OS2
Methyl 4-cyano-3-methyl-5-{[phenyl(phenylsulfanyl)acetyl]amino}thiophene-2-carboxylate chemical structure, C22H18N2O3S2, CAS 303135-09-3
Methyl 4-cyano-3-methyl-5-{[phenyl(phenylsulfanyl)acetyl]amino}thiophene-2-carboxylate
CAS 303135-09-3C22H18N2O3S2
Ethyl 5-acetyl-4-methyl-2-{[phenyl(phenylsulfanyl)acetyl]amino}-3-thiophenecarboxylate chemical structure, C24H23NO4S2, CAS 352691-41-9
Ethyl 5-acetyl-4-methyl-2-{[phenyl(phenylsulfanyl)acetyl]amino}-3-thiophenecarboxylate
CAS 352691-41-9C24H23NO4S2
Methyl 5-[(diethylamino)carbonyl]-4-methyl-2-{[phenyl(phenylthio)acetyl]amino}-3-thiophenecarboxylate chemical structure, C26H28N2O4S2, CAS 6125-76-4
Methyl 5-[(diethylamino)carbonyl]-4-methyl-2-{[phenyl(phenylthio)acetyl]amino}-3-thiophenecarboxylate
CAS 6125-76-4C26H28N2O4S2
Ethyl 5-[(dimethylamino)carbonyl]-4-methyl-2-{[phenyl(phenylthio)acetyl]amino}-3-thiophenecarboxylate chemical structure, C25H26N2O4S2, CAS 547704-43-8
Ethyl 5-[(dimethylamino)carbonyl]-4-methyl-2-{[phenyl(phenylthio)acetyl]amino}-3-thiophenecarboxylate
CAS 547704-43-8C25H26N2O4S2
4-Ethyl-5-methyl-2-[(2-phenyl-2-phenylsulfanylacetyl)amino]thiophene-3-carboxamide chemical structure, C22H22N2O2S2, CAS 543688-47-7
4-Ethyl-5-methyl-2-[(2-phenyl-2-phenylsulfanylacetyl)amino]thiophene-3-carboxamide
CAS 543688-47-7C22H22N2O2S2
Isopropyl 4-cyano-3-methyl-5-{[phenyl(phenylsulfanyl)acetyl]amino}-2-thiophenecarboxylate chemical structure, C24H22N2O3S2, CAS 353478-54-3
Isopropyl 4-cyano-3-methyl-5-{[phenyl(phenylsulfanyl)acetyl]amino}-2-thiophenecarboxylate
CAS 353478-54-3C24H22N2O3S2
Propan-2-yl 4-carbamoyl-3-methyl-5-{[phenyl(phenylsulfanyl)acetyl]amino}thiophene-2-carboxylate chemical structure, C24H24N2O4S2, CAS 438614-39-2
Propan-2-yl 4-carbamoyl-3-methyl-5-{[phenyl(phenylsulfanyl)acetyl]amino}thiophene-2-carboxylate
CAS 438614-39-2C24H24N2O4S2