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Murcko scaffold

1-Benzyl-1,3-diazinan-2-one scaffold

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
12
With full pages
3
Scaffold SMILES

O=C1NCCCN1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-1,3-diazinan-2-one page
Murcko scaffold O=C1NCCCN1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

1-(3,4-Dichlorobenzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidone chemical structure, C11H12Cl2N2O, CAS 34790-06-2
1-(3,4-Dichlorobenzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidone
CAS 34790-06-2C11H12Cl2N2O
1-[(4-Methylphenyl)methyl]-1,3-diazinan-2-one chemical structure, C12H16N2O, CAS 40016-32-8
1-[(4-Methylphenyl)methyl]-1,3-diazinan-2-one
CAS 40016-32-8C12H16N2O
1-(4-Chlorobenzyl)tetrahydropyrimidin-2(1H)-one chemical structure, C11H13ClN2O, CAS 34790-85-7
1-(4-Chlorobenzyl)tetrahydropyrimidin-2(1H)-one
CAS 34790-85-7C11H13ClN2O
2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1-(phenylmethyl)-, (5S)- chemical structure, C11H14N2O2, CAS 377093-08-8
2(1H)-Pyrimidinone, tetrahydro-5-hydroxy-1-(phenylmethyl)-, (5S)-
CAS 377093-08-8C11H14N2O2
1-((4-Aminophenyl)methyl)tetrahydro-2-pyrimidinone chemical structure, C11H15N3O, CAS 34790-78-8
1-((4-Aminophenyl)methyl)tetrahydro-2-pyrimidinone
CAS 34790-78-8C11H15N3O
Tetrahydro-1-[(4-methoxyphenyl)methyl]-2(1H)-pyrimidinone chemical structure, C12H16N2O2, CAS 34836-69-6
Tetrahydro-1-[(4-methoxyphenyl)methyl]-2(1H)-pyrimidinone
CAS 34836-69-6C12H16N2O2
1-Benzyl-1,3-diazinan-2-one chemical structure, C11H14N2O, CAS 34790-80-2
1-Benzyl-1,3-diazinan-2-one
CAS 34790-80-2C11H14N2O
1-[(1R)-1-Phenylethyl]tetrahydropyrimidin-2(1H)-one chemical structure, C12H16N2O, CAS 405145-29-1
1-[(1R)-1-Phenylethyl]tetrahydropyrimidin-2(1H)-one
CAS 405145-29-1C12H16N2O
1-Benzyl-3-methyltetrahydropyrimidin-2(1H)-one chemical structure, C12H16N2O, CAS 62417-61-2
1-Benzyl-3-methyltetrahydropyrimidin-2(1H)-one
CAS 62417-61-2C12H16N2O
(S)-1-(1-(4-Bromophenyl)ethyl)tetrahydropyrimidin-2(1H)-one chemical structure, C12H15BrN2O, CAS 1313367-24-6
(S)-1-(1-(4-Bromophenyl)ethyl)tetrahydropyrimidin-2(1H)-one
CAS 1313367-24-6C12H15BrN2O
1-Benzyl-5-methyltetrahydropyrimidin-2(1H)-one chemical structure, C12H16N2O, CAS 61282-96-0
1-Benzyl-5-methyltetrahydropyrimidin-2(1H)-one
CAS 61282-96-0C12H16N2O
4-[(Tetrahydro-3-methyl-2-oxo-1(2H)-pyrimidinyl)methyl]benzoic acid methyl ester chemical structure, C14H18N2O3, CAS 1983110-96-8
4-[(Tetrahydro-3-methyl-2-oxo-1(2H)-pyrimidinyl)methyl]benzoic acid methyl ester
CAS 1983110-96-8C14H18N2O3