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Murcko scaffold

Phthalide scaffold

781 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
781
With full pages
93
Scaffold SMILES

O=C1OCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Phthalide page
Murcko scaffold O=C1OCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 781 chemicals

6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid chemical structure, C17H20O6, CAS 483-60-3
6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid
CAS 483-60-3C17H20O6
Phthalide chemical structure, C8H6O2, CAS 87-41-2
Phthalide
CAS 87-41-2C8H6O2
3-Methyl-1(3H)-isobenzofuranone chemical structure, C9H8O2, CAS 3453-64-3
3-Methyl-1(3H)-isobenzofuranone
CAS 3453-64-3C9H8O2
3-((Dibutylamino)methyl)-4,5,6-trihydroxy-1(3H)-isobenzofuranone chemical structure, C17H25NO5, CAS 520-47-8
3-((Dibutylamino)methyl)-4,5,6-trihydroxy-1(3H)-isobenzofuranone
CAS 520-47-8C17H25NO5
Phthalide, 3-ethoxy- chemical structure, C10H10O3, CAS 16824-02-5
Phthalide, 3-ethoxy-
CAS 16824-02-5C10H10O3
Fthalide chemical structure, C8H2Cl4O2, CAS 27355-22-2
Fthalide
CAS 27355-22-2C8H2Cl4O2
5-Methyl-3H-2-benzofuran-1-one chemical structure, C9H8O2, CAS 54120-64-8
5-Methyl-3H-2-benzofuran-1-one
CAS 54120-64-8C9H8O2
Nonyl 3-oxo-1,3-dihydro-2-benzofuran-5-carboxylate chemical structure, C18H24O4, CAS 54699-44-4
Nonyl 3-oxo-1,3-dihydro-2-benzofuran-5-carboxylate
CAS 54699-44-4C18H24O4
1(3H)-Isobenzofuranone, 4,6-dimethoxy-5-hydroxy- chemical structure, C10H10O5, CAS 61052-37-7
1(3H)-Isobenzofuranone, 4,6-dimethoxy-5-hydroxy-
CAS 61052-37-7C10H10O5
Butylphthalide chemical structure, C12H14O2, CAS 6066-49-5
Butylphthalide
CAS 6066-49-5C12H14O2
Meconin chemical structure, C10H10O4, CAS 569-31-3
Meconin
CAS 569-31-3C10H10O4
3,3-Dimethylphthalide chemical structure, C10H10O2, CAS 1689-09-4
3,3-Dimethylphthalide
CAS 1689-09-4C10H10O2
1,3-Dihydro-1-oxoisobenzofuran-5-carboxylic acid chemical structure, C9H6O4, CAS 4792-29-4
1,3-Dihydro-1-oxoisobenzofuran-5-carboxylic acid
CAS 4792-29-4C9H6O4
Ethyl 1,3-dihydro-1-oxoisobenzofuran-5-carboxylate chemical structure, C11H10O4, CAS 23405-31-4
Ethyl 1,3-dihydro-1-oxoisobenzofuran-5-carboxylate
CAS 23405-31-4C11H10O4
6-Aminophthalide chemical structure, C8H7NO2, CAS 57319-65-0
6-Aminophthalide
CAS 57319-65-0C8H7NO2
3-Chlorophthalide chemical structure, C8H5ClO2, CAS 6295-21-2
3-Chlorophthalide
CAS 6295-21-2C8H5ClO2
1(3H)-Isobenzofuranone, 3-bromo- chemical structure, C8H5BrO2, CAS 6940-49-4
1(3H)-Isobenzofuranone, 3-bromo-
CAS 6940-49-4C8H5BrO2
Cyclopaldic acid chemical structure, C11H10O6, CAS 477-99-6
Cyclopaldic acid
CAS 477-99-6C11H10O6
7-Amino-4,5,6-triethoxy-3-hydroxyphthalide chemical structure, C14H19NO6, CAS 103658-46-4
7-Amino-4,5,6-triethoxy-3-hydroxyphthalide
CAS 103658-46-4C14H19NO6
3-Hydroperoxy-3-methylphthalide chemical structure, C9H8O4, CAS 90094-81-8
3-Hydroperoxy-3-methylphthalide
CAS 90094-81-8C9H8O4
7-Hydroxy-6-methoxyphthalide chemical structure, C9H8O4, CAS 29809-16-3
7-Hydroxy-6-methoxyphthalide
CAS 29809-16-3C9H8O4
Corollosporine chemical structure, C14H18O4, CAS 211441-46-2
Corollosporine
CAS 211441-46-2C14H18O4
6-Methoxy-3-(trichloromethyl)-2-benzofuran-1(3H)-one chemical structure, C10H7Cl3O3, CAS 82735-28-2
6-Methoxy-3-(trichloromethyl)-2-benzofuran-1(3H)-one
CAS 82735-28-2C10H7Cl3O3
Asperdurin chemical structure, C15H18O5, CAS 118446-32-5
Asperdurin
CAS 118446-32-5C15H18O5