CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
7
With full pages
3
Scaffold SMILES

O=C(NNS(=O)(=O)c1ccccc1)c1csc(-n2cccn2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NNS(=O)(=O)c1ccccc1)c1csc(-n2cccn2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N'-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide chemical structure, C15H12F3N5O3S2, CAS 955962-79-5
N'-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide
CAS 955962-79-5C15H12F3N5O3S2
4-Fluoro-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide chemical structure, C15H11F4N5O3S2, CAS 955963-17-4
4-Fluoro-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide
CAS 955963-17-4C15H11F4N5O3S2
4-Bromo-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide chemical structure, C15H11BrF3N5O3S2, CAS 956961-83-4
4-Bromo-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide
CAS 956961-83-4C15H11BrF3N5O3S2
3,4-Dimethoxy-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide chemical structure, C17H16F3N5O5S2, CAS 956782-90-4
3,4-Dimethoxy-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide
CAS 956782-90-4C17H16F3N5O5S2
N'-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-2-nitrobenzenesulfonohydrazide chemical structure, C15H11F3N6O5S2, CAS 956204-30-1
N'-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-2-nitrobenzenesulfonohydrazide
CAS 956204-30-1C15H11F3N6O5S2
N-(4-{[2-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)hydrazino]sulfonyl}phenyl)acetamide chemical structure, C17H15F3N6O4S2, CAS 956372-21-7
N-(4-{[2-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)hydrazino]sulfonyl}phenyl)acetamide
CAS 956372-21-7C17H15F3N6O4S2
4-Methoxy-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide chemical structure, C16H14F3N5O4S2, CAS 956795-64-5
4-Methoxy-N'-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)benzenesulfonohydrazide
CAS 956795-64-5C16H14F3N5O4S2