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Murcko scaffold

Ring system with 3 rings and 21 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
14
With full pages
12
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1cc(-c2ccc[nH]2)n[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1cc(-c2ccc[nH]2)n[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N'-(3-Hydroxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C16H15N5O2, CAS 303104-83-8
N'-(3-Hydroxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 303104-83-8C16H15N5O2
(Z)-N'-(3-Bromobenzylidene)-3-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C16H14BrN5O, CAS 403649-21-8
(Z)-N'-(3-Bromobenzylidene)-3-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 403649-21-8C16H14BrN5O
Methyl 4-[(E)-(2-{[3-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazol-5-yl]carbonyl}hydrazinylidene)methyl]benzoate chemical structure, C18H17N5O3, CAS 1285546-55-5
Methyl 4-[(E)-(2-{[3-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazol-5-yl]carbonyl}hydrazinylidene)methyl]benzoate
CAS 1285546-55-5C18H17N5O3
N'-(4-Isopropylbenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C19H21N5O, CAS 303095-22-9
N'-(4-Isopropylbenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 303095-22-9C19H21N5O
N'-{(E)-[4-(Diethylamino)phenyl]methylidene}-3-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C20H24N6O, CAS 302918-26-9
N'-{(E)-[4-(Diethylamino)phenyl]methylidene}-3-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 302918-26-9C20H24N6O
N'-(2-Methoxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C17H17N5O2, CAS 303104-86-1
N'-(2-Methoxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 303104-86-1C17H17N5O2
N'-(4-Chlorobenzylidene)-5-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-3-carbohydrazide chemical structure, C16H14ClN5O, CAS 303106-80-1
N'-(4-Chlorobenzylidene)-5-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-3-carbohydrazide
CAS 303106-80-1C16H14ClN5O
N'-(2-Ethoxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C18H19N5O2, CAS 402514-88-9
N'-(2-Ethoxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 402514-88-9C18H19N5O2
N'-(4-Methylbenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C17H17N5O, CAS 303106-82-3
N'-(4-Methylbenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 303106-82-3C17H17N5O
3-(1-Methyl-1H-pyrrol-2-yl)-N'-[(E)-(2,4,5-trimethoxyphenyl)methylidene]-1H-pyrazole-5-carbohydrazide chemical structure, C19H21N5O4, CAS 303106-79-8
3-(1-Methyl-1H-pyrrol-2-yl)-N'-[(E)-(2,4,5-trimethoxyphenyl)methylidene]-1H-pyrazole-5-carbohydrazide
CAS 303106-79-8C19H21N5O4
N'-(4-Fluorobenzylidene)-5-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-3-carbohydrazide chemical structure, C16H14FN5O, CAS 302918-24-7
N'-(4-Fluorobenzylidene)-5-(1-methyl-1H-pyrrol-2-yl)-1H-pyrazole-3-carbohydrazide
CAS 302918-24-7C16H14FN5O
N'-(2-HO-3-Meo-benzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C17H17N5O3, CAS 402509-44-8
N'-(2-HO-3-Meo-benzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 402509-44-8C17H17N5O3
N'-(5-BR-2-HO-Benzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C16H14BrN5O2, CAS 302918-25-8
N'-(5-BR-2-HO-Benzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 302918-25-8C16H14BrN5O2
N'-(4-Hydroxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C16H15N5O2, CAS 303104-85-0
N'-(4-Hydroxybenzylidene)-3-(1-ME-1H-pyrrol-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 303104-85-0C16H15N5O2