CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

261 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
261
With full pages
99
Scaffold SMILES

O=C(CSc1nnc(-c2ccco2)[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(-c2ccco2)[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 261 chemicals

2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-phenylacetamide chemical structure, C15H14N4O2S, CAS 384859-15-8
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-phenylacetamide
CAS 384859-15-8C15H14N4O2S
2-((5-(2-Furyl)-4-ME-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide chemical structure, C16H16N4O3S, CAS 498550-72-4
2-((5-(2-Furyl)-4-ME-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide
CAS 498550-72-4C16H16N4O3S
N-(4-Ethoxyphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C17H18N4O3S, CAS 498550-78-0
N-(4-Ethoxyphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 498550-78-0C17H18N4O3S
2-((4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-N-(2-methoxy-5-methylphenyl)acetamide chemical structure, C19H20N4O3S, CAS 618879-93-9
2-((4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-N-(2-methoxy-5-methylphenyl)acetamide
CAS 618879-93-9C19H20N4O3S
2-((4-Amino-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-ethylphenyl)acetamide chemical structure, C16H17N5O2S, CAS 768287-00-9
2-((4-Amino-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-ethylphenyl)acetamide
CAS 768287-00-9C16H17N5O2S
2-((4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxyphenyl)acetamide chemical structure, C18H18N4O3S, CAS 575466-99-8
2-((4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxyphenyl)acetamide
CAS 575466-99-8C18H18N4O3S
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-{[5-(furan-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H19ClN4O3S, CAS 578754-20-8
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-{[5-(furan-2-yl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 578754-20-8C19H19ClN4O3S
2-((4-Amino-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-mesitylacetamide chemical structure, C17H19N5O2S, CAS 577788-57-9
2-((4-Amino-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-mesitylacetamide
CAS 577788-57-9C17H19N5O2S
2-(4-Amino-5-(2-furyl)(1,2,4-triazol-3-ylthio))-N-(6-ethyl-2-methylphenyl)acet amide chemical structure, C17H19N5O2S, CAS 577694-64-5
2-(4-Amino-5-(2-furyl)(1,2,4-triazol-3-ylthio))-N-(6-ethyl-2-methylphenyl)acet amide
CAS 577694-64-5C17H19N5O2S
2-((4-Amino-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide chemical structure, C16H17N5O2S, CAS 585561-99-5
2-((4-Amino-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide
CAS 585561-99-5C16H17N5O2S
N-(4-Fluorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C15H13FN4O2S, CAS 569644-85-5
N-(4-Fluorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 569644-85-5C15H13FN4O2S
N-(4-Ethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C17H18N4O2S, CAS 510713-64-1
N-(4-Ethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 510713-64-1C17H18N4O2S
N-(4-Chlorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C15H13ClN4O2S, CAS 497837-60-2
N-(4-Chlorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 497837-60-2C15H13ClN4O2S
N-(3,4-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C17H18N4O2S, CAS 557069-50-8
N-(3,4-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 557069-50-8C17H18N4O2S
N-(3-Chlorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C15H13ClN4O2S, CAS 569644-76-4
N-(3-Chlorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 569644-76-4C15H13ClN4O2S
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-methylphenyl)acetamide chemical structure, C16H16N4O2S, CAS 557069-23-5
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-methylphenyl)acetamide
CAS 557069-23-5C16H16N4O2S
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methylphenyl)acetamide chemical structure, C16H16N4O2S, CAS 557069-37-1
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methylphenyl)acetamide
CAS 557069-37-1C16H16N4O2S
N-(2-Ethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C17H18N4O2S, CAS 557069-44-0
N-(2-Ethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 557069-44-0C17H18N4O2S
N-(2,3-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C17H18N4O2S, CAS 557069-47-3
N-(2,3-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 557069-47-3C17H18N4O2S
N-(3,5-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C17H18N4O2S, CAS 557069-57-5
N-(3,5-Dimethylphenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 557069-57-5C17H18N4O2S
2-((4-Ethyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide chemical structure, C16H15FN4O2S, CAS 557069-81-5
2-((4-Ethyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide
CAS 557069-81-5C16H15FN4O2S
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide chemical structure, C16H16N4O3S, CAS 498550-74-6
2-{[5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide
CAS 498550-74-6C16H16N4O3S
N-(2-Fluorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C15H13FN4O2S, CAS 498550-94-0
N-(2-Fluorophenyl)-2-{[5-(furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 498550-94-0C15H13FN4O2S
2-((4-Ethyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide chemical structure, C16H15FN4O2S, CAS 603978-82-1
2-((4-Ethyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide
CAS 603978-82-1C16H15FN4O2S