Murcko scaffold
Ring system with 2 rings and 23 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 23
- Chemicals
- 7
- With full pages
- 1
Scaffold SMILES
O=C1CNC(=O)CNC(=O)C(=Cc2ccccc2)NC(=O)CN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
Tentoxin
CAS 28540-82-1C22H30N4O4
trans-(3S,6S,12E)-12-Benzylidene-1,6,7-trimethyl-3-(2-methylpropyl)-1,4,7,10-tetrazacyclododecane-2,5,8,11-tetrone
CAS 65452-16-6C22H30N4O4
Cyclo(D-alanyl-L-leucyl-(Z)-alpha,beta-didehydrophenylalanylglycyl)
CAS 108233-94-9C20H26N4O4
Cyclo(L-alanyl-D-leucyl-(Z)-alpha,beta-didehydro-N-methylphenylalanylglycyl)
CAS 108233-95-0C21H28N4O4
Cyclo(N-methyl-L-alanyl-L-leucyl-(Z)-alpha,beta-didehydrophenylalanylglycyl)
CAS 108340-84-7C21H28N4O4
Cyclo(N-methyl-D-alanylglycyl-alpha,beta-didehydro-N-methylphenylalanyl-L-leucyl)
CAS 67683-83-4C22H30N4O4
Tentoxin-d3
CAS 1426437-58-2C22H30N4O4
Related scaffolds
Same ring framework with different atoms or bond orders
